research Marie Unna Hereditary Hypotrichosis Caused by a Novel Mutation in the Human Hairless Transcript
A new mutation in the HR gene causes hair loss in a specific family.
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research Congenital Atrichia and Hypotrichosis
The document emphasizes the importance of correctly identifying and classifying genetic hair disorders to help diagnose related health conditions.
research Punch Transplantation in Early Androgenetic Alopecia
Early transplantation helps avoid embarrassment and allows relaxed transplant sessions, but be cautious with young patients with thinning hair.
research Topical Fulvestrant Solution Has No Effect on Male and Postmenopausal Female Androgenetic Alopecia: Results from Two Randomized, Proof-of-Concept Studies
Fulvestrant solution doesn't help hair loss in men and postmenopausal women.
research Epithelial-Mesenchymal Interaction in Hair Regeneration and Skin Wound Healing
Hair and skin healing involve complex cell interactions controlled by specific molecules and pathways, and hair follicle cells can help repair skin wounds.
research Telogen Effluvium Associated with Eosinophilia-Myalgia Syndrome
Hair loss in a woman with eosinophilia-myalgia syndrome improved after stopping L-tryptophan and starting treatment.
research Hair Microscopy: An Easy Adjunct to Diagnosis of Systemic Diseases in Children
Hair microscopy is a simple and cost-effective method to help diagnose systemic diseases in children.
research Cucurbitacin Promotes Hair Growth in Mice by Inhibiting the Expression of Fibroblast Growth Factor 18
Cucurbitacin helps mice grow hair by blocking a protein that stops hair growth.
research Diagnostic Challenges in Determining Alopecia Areata
Diagnosing alopecia areata is challenging and requires careful examination and various tests to distinguish it from other hair loss types.
research A Rare Case of Biotinidase Deficiency
An infant with seizures and hair loss was diagnosed with biotinidase deficiency and treated successfully with biotin.
research Whole-Genome SNP Genotyping Mapped a Novel Locus for Hereditary Hypotrichosis on Chromosome 2q31.1–q32.2
Researchers found a new area on chromosome 2 linked to a genetic hair loss condition.
research Trichoscopic Findings in Androgenetic Alopecia and Their Clinical Correlation
Trichoscopy helps diagnose and monitor hair loss, showing different signs at various stages of hair thinning.
research Genetic Basis of Skin Appendage Development
Hair, teeth, and mammary glands develop similarly at first but use different genes later.
research Trichoscopy in Alopecias: Diagnosis Simplified
Trichoscopy is a useful, non-invasive way to diagnose different types of hair loss.
research Hirsutism and the Variable Response of the Pilosebaceous Unit to Androgens
Different women's hair and skin glands respond to hormones in varied ways, which can cause unwanted hair growth even with normal hormone levels, and more research is needed to treat this effectively.
research Treatment of Male Pattern Baldness with Botulinum Toxin: A Pilot Study
Botox increased hair count in men with baldness and might work by improving scalp blood flow.
research Analysis of the FGF Gene Family Provides Insights into Aquatic Adaptation in Cetaceans
Whale genes show changes that help them live in water, like less hair and better flippers.
research Transgenic Kallikrein 14 Mice Display Major Hair Shaft Defects Associated with Desmoglein 3 and 4 Degradation, Abnormal Epidermal Differentiation, and IL-36 Signature
Mice with extra human KLK14 had hair and skin problems, including weaker cell bonds and inflammation, linked to Netherton syndrome.
research Highly Prevalent LIPH Founder Mutations Causing Autosomal Recessive Woolly Hair/Hypotrichosis in Japan and the Genotype/Phenotype Correlations
LIPH mutations in Japan cause varying degrees of hair loss and woolly hair.
research Growth Hormone and the Human Hair Follicle
Growth hormone levels affect hair growth and loss, with too much causing excess hair and too little leading to hair loss.
research Eyebrow Restoration: The Approach, Considerations, and Technique in Follicular Unit Transplantation
Successful eyebrow restoration can be done using careful hair transplant techniques and choosing the right patients.
research Classification of Male-Pattern Hair Loss
No current system perfectly classifies male-pattern hair loss, indicating a need for a new system for better diagnosis and treatment.
research Alopecia as a Systemic Disease
Hair loss can indicate or worsen with systemic diseases, and treating the underlying condition is important.
research Clinical, Histological, and Trichoscopic Correlations in Scalp Disorders
Trichoscopy helps diagnose hair and scalp problems but isn't always definitive and should be used with other methods.
research A Cross-Sectional Study of Plasma Trace Elements and Vitamins Content in Androgenetic Alopecia in Men
Men with hair loss may lack zinc, copper, and vitamin D; supplements could help.
research Investigation of Transcriptional Gene Profiling in Normal Murine Hair Follicular Substructures Using Next-Generation Sequencing to Provide Potential Insights into Skin Disease
Hair follicles have a more inactive cell cycle than other skin cells, which may help develop targeted therapies for skin diseases and cancer.
research Rickets with Alopecia Signals Vitamin D Dependent Rickets Type II
A child with rickets and hair loss might have a rare type of rickets that doesn't improve much with usual vitamin D and calcium treatment.
research Scalp and Calvarial Reconstruction
The conclusion is that closing scalp wounds is possible, but restoring hair without donor material is still a major challenge.
research Woolly Antics Between the Sheaths
Lipase H is important for hair follicle function and shaping hair fibers.
research Restoration of Follicular β-Catenin Signaling by Mesenchymal Stem Cells Promotes Hair Growth in Mice with Androgenetic Alopecia
The study demonstrates that human umbilical cord mesenchymal stem cells (hUCMSCs) can promote hair growth in mice with androgenetic alopecia (AGA) by activating the Wnt/β-catenin signaling pathway. This activation reduces apoptosis in dermal papilla cells (DPCs) and enhances the proliferation of hair follicle stem cells (HFSCs), leading to increased hair follicle density and skin thickness. The research involved 30 mice and suggests that hUCMSCs could offer a promising alternative to current AGA treatments by improving the hair follicle growth environment and signaling.