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Stem cell self-renewal is complex and needs more research for full understanding.

Different types of stem cells exist within individual skin layers, and they can adapt to damage, transplantation, or tumor growth. These cells are regulated by their environment and genetic factors. Tumor growth is driven by expanding, genetically altered cells, not long-lived mutant stem cells. There's evidence of cancer stem cells in skin tumors. Other cells, bacteria, and genetic factors help maintain balance and contribute to disease progression. A method for growing mini organs from single cells has been developed.

Men generally have more severe COVID-19 cases and higher death rates than women due to biological differences.

Asia has made significant progress in tissue engineering and regenerative medicine, but wider clinical use requires more development.

New single-cell analysis techniques are improving our understanding of stem cells and could help in treating diseases.

Mutant CDP/Cux protein causes hair defects and reduced male fertility in mice.

Certain genetic variations in the AR and ERβ genes can affect androgen levels in women.

The Wnt/β-catenin pathway is important for tissue development and has potential in regenerative medicine, but requires more research for therapeutic use.

Mice studies show that Protein Phosphatase 2A is crucial for cell growth, development, and disease prevention.

The skin protects the body and is constantly renewed by stem cells; disruptions can lead to cancer.

Skin development in mammals is controlled by key proteins and signals from underlying cells, involving stem cells for maintenance and repair.

The TGF-β family helps control how cells change and move, affecting skin, hair, and organ development.

Skin has specialized touch receptors that can tell different sensations apart.

The tumor suppressor gene FLCN affects mitochondrial function and energy use in cells.

Certain mice without specific receptors or mast cells don't lose hair from stress.

The circadian clock influences the behavior and regeneration of stem cells in the body.

Progress has been made in skin and nerve regeneration, but more research is needed to improve methods and ensure safety.

Advanced human skin models improve drug development and could replace animal testing.

Cancer can hijack the body's cell repair system to promote tumor growth, and targeting this process may improve cancer treatments.

Melanocyte development from neural crest cells is complex and influenced by many factors, and better understanding could help treat skin disorders.

Researchers found 63 genes linked to male-pattern baldness, which could help in understanding its biology and developing new treatments.

Using CRISPR for gene editing in the body is promising but needs better delivery methods to be more efficient and specific.

Wnt signaling may be linked to heart diseases in aging and could be a target for future treatments.

Environmental factors at different levels control hair stem cell activity, which could lead to new hair growth and alopecia treatments.

Products should be called 'sperm-safe' only after thorough, well-designed tests.

Skin stem cells maintain and repair the outer layer of skin, with some types being essential for healing wounds.

Parathyroid hormone-related protein helps control hair growth phases in mice.

Eating healthy, exercising, and taking certain supplements can help manage Polycystic Ovary Syndrome symptoms.

The study suggests that motor neurons created from stem cells of patients with spinal and bulbar muscular atrophy show signs of the disease, including changes in protein levels and cell functions.

The document concludes that future heart disease research should account for sex-specific differences to improve diagnosis, treatment, and outcomes.