research Treatment of Widespread Alopecia Areata in Young Patients with Monthly Oral Corticosteroid Pulse
Monthly oral corticosteroid pulses effectively treat widespread alopecia areata in young patients.
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research A Glutathione-Dependent Control of the Indole Butyric Acid Pathway Supports Arabidopsis Root System Adaptation to Phosphate Deprivation
Glutathione helps Arabidopsis roots adapt to low phosphate by regulating a specific growth pathway.
research Cross-Linked Features of Mouse Pelage Hair Resistant to Detergent Extraction
Some mutant mice have hair with abnormal cross-linking, mainly in the cuticle, not affecting other hair parts.
research Demethylation of Methionine and Keratin Damage in Human Hair
Copper and iron cause keratin damage in hair by converting methionine to homocysteine.
research Powder Shampoo Formulation with Antioxidant Activity: In Vitro Perspectives
The powder shampoo with cinnamon extract has strong antioxidant properties and is eco-friendly.
research Veterinary Pharmacology
Some plant extracts may treat livestock diseases, certain animal treatments are safe and effective, but more research on drug safety and resistance is needed.
research The Nuclear Vitamin D Receptor: Biological and Molecular Regulatory Properties Revealed
The vitamin D receptor is crucial for bone health and affects various body systems, with mutations potentially leading to disease.
research Cutaneous Metabolism of Vitamin B-6
An enzyme other than TNAP might be responsible for vitamin B-6 metabolism in the skin.
research Proteins as Hair Styling Agents
Proteins like BSA and keratin can effectively style hair and protect it, offering eco-friendly alternatives to chemical products.
research Mutations in Homocysteine Metabolism Genes Increase Keratin N-Homocysteinylation and Damage in Mice
Genetic mutations that disrupt homocysteine breakdown lead to increased damage in mouse hair keratin.
research Cross-Linked Features of Mouse Pelage Hair Resistant to Detergent Extraction
Two mouse mutants have defective hair cuticle cross-linking.
research Azasteroids as Inhibitors of Testosterone 5α-Reductase in Mammalian Skin
Certain 4-azasteroids are effective at blocking the enzyme that processes testosterone in human skin and could help treat acne, excessive hair growth, and male pattern baldness.
research Finasteride Blocks Progesterone Synthesis in MA-10 Leydig Tumor Cells
Finasteride blocks progesterone production in specific tumor cells, potentially causing side effects.
research Cloning of a Functional Vitamin D Receptor from the Lamprey, an Ancient Vertebrate Lacking a Calcified Skeleton and Teeth
Lampreys have a functional vitamin D receptor that may help detoxify harmful substances.
research Trichohyalin: Presence in the Granular Layer and Stratum Corneum of Normal Human Epidermis
Trichohyalin is also found in the outer layers of normal human skin.
research Cutaneous Application of Alpha-Methylspermidine Activates the Growth of Resting Hair Follicles in Mice
Putting α-methylspermidine on mouse skin can start hair growth.
research Determination of Finasteride and Its Metabolite in Urine by Dispersive Liquid-Liquid Microextraction Combined with Field-Enhanced Sample Stacking and Sweeping
New method accurately measures finasteride and M3 in urine, helping evaluate pharmacokinetics.
research Production of Biologically Active Oxidized Derivatives of Finasteride Through Metabolism by Aspergillus Niger Culture
Aspergillus niger culture creates two finasteride derivatives with enzyme-inhibiting effects.
research Structural and Functional Studies of L-PGDS and SMPDL3A Enzymes in Lipid Signaling Family
L-PGDS has specific binding sites for its functions and could help in drug delivery system design.
research Vitamin D Receptor: Molecular Signaling and Actions of Nutritional Ligands in Disease Prevention
Vitamin D receptor interacts with certain dietary components to help prevent diseases and regulate hair growth.
research Serotoninergic And Melatoninergic Systems Are Fully Expressed In Human Skin
Human skin can make serotonin and melatonin.
research Generic Development of Topical Dermatologic Products: Formulation Development, Process Development, and Testing
The document concludes that developing generic topical drugs requires ensuring they match the original in quality, composition, and structure, and often involves complex testing and regulatory steps.
research Oxidative Stress-Associated Senescence in Dermal Papilla Cells of Men with Androgenetic Alopecia
Oxidative stress affects hair loss in men with androgenetic alopecia.
research Characterization of the Serotoninergic System in the C57BL/6 Mouse Skin
Mouse skin can produce and process serotonin, with variations depending on hair cycle, body location, and mouse strain.
research Anti-Androgenic Activities of Ganoderma Lucidum
Ganoderma lucidum, a type of mushroom, may help treat enlarged prostate by blocking testosterone conversion.
research Sulfation of Minoxidil by Human Liver Phenol Sulfotransferase
Minoxidil activates hair growth by being sulfated by P-PST in the human liver.
research Effect of Cuscuta Reflexa Roxb on Androgen-Induced Alopecia
Cuscuta reflexa extract may help treat hair loss caused by hormones.
research Topical Application of a Protein Kinase C Inhibitor Reduces Skin and Hair Pigmentation
Applying a specific inhibitor lightens skin and hair color.
research Effects of Nitric Oxide on Skin Burn Wound Healing
Nitric oxide gel helps heal skin burns faster by improving skin growth, hair regrowth, and blood vessel formation.
research Murine Skin as a Target for Melatonin Bioregulation
Melatonin affects mouse skin and may regulate skin functions.