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Testosterone treatment effectively causes male physical development in transgender male adolescents but may lead to side effects like acne, higher BMI and blood pressure, lower good cholesterol, and decreased bone density.

Blocking IL-12/IL-23p40 helped reverse severe hair loss in patients.

Dermal papilla cells help wounds heal better and can potentially grow new hair.

The document concludes that targeting the androgen receptor may be a promising breast cancer treatment, especially for certain types.

Sox2-positive dermal papilla cells have unique characteristics and contribute more to skin and hair follicle formation than Sox2-negative cells.

Overexpressing the mineralocorticoid receptor in mouse skin causes skin thinning, early skin barrier development, eye issues, and hair loss.

Androgens cause skin issues like acne and hair growth in women, often due to PCOS, and can be treated with medication and lifestyle changes.

No cure for female pattern hair loss, but various effective treatments exist.

Mycophenolate mofetil was effective for most patients in treating scarring hair loss, but some had side effects.

The conclusion is that the best initial treatment for hirsutism is usually oral contraceptives, with the addition of antiandrogens or insulin sensitizers if needed, and topical eflornithine or laser treatments as supplementary options.

Certain bacteria and fungi are linked to healthy scalps and dandruff, suggesting that the scalp's microbial balance affects its health.

Some systemic treatments work for nail psoriasis but can have serious side effects.

Myo-inositol helps improve skin conditions and metabolic profiles in young women with PCOS.

Women with excess body hair feel psychological distress influenced by societal beauty standards, but distress isn't directly linked to the amount of hair.

The transscrotal testosterone patch normalizes hormone levels in men with AIDS and weight loss but does not improve weight, body mass, or quality of life.

Topical JAK inhibitors may help treat some skin conditions but need more research.

Children with atopic dermatitis often have sleep problems due to itching and may benefit from melatonin, which helps with sleep and skin symptoms.

Diane 35 plus finasteride is more effective for treating hirsutism.

Scalp cooling can reduce chemotherapy-induced hair loss and should be available in all hospitals.

The cause of Frontal Fibrosing Alopecia is unclear, diagnosis involves clinical evaluation and various treatments exist, but their effectiveness is uncertain.

Light can turn on hair growth cells through a nerve path starting in the eyes.

RTA 408 cream protects mice from radiation skin damage.

PPAR agonists show promise for skin conditions but need more research before being a main treatment.

Cats with atopic dermatitis often have severe, year-round itching and respond well to certain treatments.

Mitoxantrone with a corticosteroid helps manage symptoms for some advanced prostate cancer patients but doesn't extend life.

There are still challenges in diagnosing and treating chronic skin diseases, but there is hope for future improvements.

Certain proteins, caspases-1 and -11, are important in the early development of skin inflammation in mice.

Seborrheic dermatitis lowers quality of life more for women, younger people, and those with more education.

The TRPV3 gene mutation affects hair growth by keeping mice in the growth phase longer, which could help treat hair loss.

The conclusion is that individual differences in COVID-19 severity are influenced by factors like age, sex, race, and genetics, which are important for personalized medicine.