This review explores the Ayurvedic perspective of Indralupta, linked to Alopecia areata in modern medicine, highlighting disease progression through Tridosha imbalance and comparing it with contemporary understanding of Alopecia's pathogenesis.
August 2025 in “International Journal of Ayurveda360” In this randomized controlled trial, the combination of Bhringaraja Taila Shiroabhyanga and Yastimadhuka Taila Nasya was found to significantly improve hair density, reduce hair fall, and decrease scalp visibility in females with Khalitya compared to Nasya alone, with no reported adverse effects.
September 2021 in “International Ayurvedic Medical Journal” This study reported that in 31 patients with diffuse hair loss, daily application of Bhringraj oil significantly reduced hair fall, dandruff, itching, and dryness over four weeks, without any adverse reactions.
59 citations
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September 2021 in “Journal of Allergy and Clinical Immunology” This study found IL-17/IL-36 signaling to be predominant in both endotypes of Netherton syndrome, with distinct molecular profiles between NS-ILC and NS-SE lesions, offering potential therapeutic targets.
5 citations
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January 2011 in “Archives de Pédiatrie” This study illustrates the severe neonatal clinical presentation of Netherton syndrome, which can be fatal despite intensive care, highlighting a specific homozygous mutation (c.1431-12G > A) associated with lethal cases.
1 citations
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January 2014 in “Journal of clinical & experimental dermatology research” This study suggests that the fresh leaf extracts of Naringi crenulata may promote hair growth in Wistar rats, potentially due to the presence of terpenoids and flavonoids.
3 citations
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June 2023 in “Molecules/Molecules online/Molecules annual” The researchers reviewed cepharanthine, a long-used bisbenzylisoquinoline alkaloid, for its antiviral properties, including significant inhibition of SARS-CoV-2. They discussed cepharanthine's other pharmacological actions, highlighted plasma membrane fluidity as a key antiviral mechanism, and examined its safety, bioavailability, and potential for new clinical applications.
39 citations
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December 2012 in “The American Journal of Human Genetics” This study identified mutations in the SNRPE gene that may disrupt hair growth, linking a spliceosome component to hereditary hair loss disorders.
December 2025 in “International Journal of Molecular Sciences” This study found that an aqueous extract of Bacopa procumbens improved motor function and preserved neuronal structure in a mouse model of Parkinson's disease, suggesting its neuroprotective potential.
May 2022 in “Голова и шея.” This study found a direct correlation between chronic tonsillitis and increased NETosis activity in peripheral blood and palatine tonsil lacunae.
4 citations
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April 2008 in “Experimental Dermatology” This review hypothesizes that nicotine plays a crucial role in the pathogenesis of hidradenitis suppurativa by promoting inflammation and microbial growth, suggesting that anticholinergic agents might be a potential treatment strategy, but reports no new clinical findings.
July 2026 in “International Journal for Research in Applied Science and Engineering Technology” This study explored the use of Kasisadi Lepa, a classical herbo-mineral formulation, and found its components could reduce dandruff by addressing scalp inflammation, microbial growth, and tissue damage with potential integration into long-term scalp health strategies.
2 citations
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May 2011 in “International Journal of Dermatology” This case report details a 12-year-old boy from rural south India diagnosed with syringolymphoid hyperplasia, which presented with alopecia and anhidrosis.
October 2025 in “Cermin Dunia Kedokteran” This review discusses personalized treatment strategies and management approaches for chronic obstructive pulmonary disease (COPD), emphasizing the need for multi-aspect assessments, but reports no new clinical findings.
July 2017 in “Journal of Ayurveda and Integrated Medical Sciences” This study reported that Ayurvedic treatment involving the internal administration of Vidangarishta, Krimikutararasa, and Shatavari Guda, alongside external papaya exudate application, led to significant, rapid, and lasting improvements in alopecia areata in a week-long trial.
125 citations
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May 2019 in “Phytomedicine” This review discusses the historical development, mechanisms of action, and potential new clinical applications of the drug cepharanthine, highlighting its multi-faceted pharmacological properties; it reports no new clinical results.
June 2021 in “International Ayurvedic Medical Journal” In this source, a case of a female patient with indralupta (alopecia areata) was successfully treated using Ayurvedic methods, specifically jaluaka, haridra, and nimbalepa, suggesting an effective alternative to corticosteroids, which have harmful side effects and are unsuitable for long-term use.
January 2025 in “Annals of Clinical Reviews & Case Reports” This study emphasizes the importance of early diagnosis and a collaborative healthcare team in managing Sjogren’s Disease due to its complex nature and symptom variability, highlighting that timely treatment is crucial to prevent further damage.
December 2025 in “Zenodo (CERN European Organization for Nuclear Research)” In this study, researchers evaluated Chyavanaprasam K Tab, an Ayurvedic tablet, finding it to have consistent quality and safety, with potential benefits for fatigue relief, immune support, and hair growth. It is also deemed suitable for diabetic individuals due to its sugar-free composition.
1 citations
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December 2024 in “BMC Genomics” This study used transcriptome analysis to explore the genetic mechanisms behind the development and seasonal variation of nuptial pads in R. chensinensis, identifying key genes and processes that suggest the pads' development involves complex regulatory pathways, particularly those related to cell cycle and hormone synthesis.
8 citations
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August 2020 in “PLOS Computational Biology” This study presents a computational approach, CATNIP, which repurposes drugs using only their biological and chemical information, predicting new uses like adrenergic uptake inhibitors for Parkinson's and vandetanib for Type 2 Diabetes.
1 citations
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November 2003 in “SKINmed Dermatology for the Clinician” This case report describes a 17-year-old patient diagnosed with Netherton syndrome, characterized by pruritic dry skin, short brittle hair, and elevated IgE levels, treated with antihistamines and emollients.
3 citations
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January 2012 This study concluded that human sweat contributes to hair cortisol concentrations, potentially affecting interpretations of chronic stress and OSA-related stress levels, with CPAP reducing psychological but not physiological stress after 3 months.
2 citations
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October 2013 in “Journal of Veterinary Internal Medicine” This study reports the first documented case of sweat hypersensitivity and progressive sebaceous adenitis in a horse, highlighting the potential for sweat-induced urticaria when exercising or under sedation.
January 2024 in “International Ayurvedic medical journal” This study explores how Ayurveda concepts, specifically Prakruti, relate to male pattern baldness, suggesting that individual constitutional types may predict susceptibility to earlier hair loss when influenced by modern lifestyle factors.
41 citations
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December 2008 in “Pediatric Dermatology” This case report indicates that trichoscopy may significantly improve the diagnosis of Netherton syndrome by noninvasively identifying typical hair abnormalities without the need to pull hair.
6 citations
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May 2023 in “Molecules” In this study, dry powder inhalers containing Cepharanthine were administered to rats with acute lung injury, significantly reducing pulmonary edema, hemorrhage, and inflammatory markers, suggesting its potential as an effective anti-inflammatory treatment when inhaled directly into the lungs.
1 citations
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January 2023 in “Journal of Pharmacognosy and Phytochemistry” This study provided detailed anatomical, physico-chemical, and chromatographic analyses to differentiate Dracaena trifasciata from potential adulterants in traditional medicine.
This study found that an ethanolic extract of Semicarpus anacardium nuts reduced blood glucose levels and improved enzyme activities related to carbohydrate metabolism in normal rats.
January 2020 in “International Research Journal of Ayurveda & Yoga” This article discusses the Ayurvedic perspective on hair health, highlighting the role of aasthi dhatu nourishment and herbal treatments, but it reports no new clinical results.