TLDR A 17-year-old with Netherton syndrome has dry, itchy skin, brittle hair, and high IgE levels, treated with antihistamines and emollients.
A 17-year-old Egyptian patient was diagnosed with Netherton syndrome, characterized by pruritic dry skin, short brittle hair, and a history of erythroderma and recurrent infections since infancy. Despite normal developmental milestones and intelligence, the patient exhibited scaly, migratory skin lesions and sparse eyebrows and lashes. Laboratory tests revealed elevated IgE levels, and hair microscopy showed trichorrhexis invaginata, or bamboo hair. Treatment included antihistamines, emollients, and 10% urea. The family history was notable for eczema and allergic rhinitis but not ichthyotic disorders.
124 citations
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January 1995 in “The journal of allergy and clinical immunology/Journal of allergy and clinical immunology/The journal of allergy and clinical immunology” Netherton's syndrome is linked to high IgE levels and unique skin and hair symptoms, and may improve with ammonium lactate lotion and allergy management.
1 citations
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January 2013 in “Elsevier eBooks” The document reviews various hair and nail disorders, their causes, and treatments, emphasizing the need for proper diagnosis and the link between nail changes and systemic diseases.
January 2017 in “Springer eBooks” The document explains various skin conditions and their treatments.
36 citations
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January 2012 in “International Journal of Trichology” Losing eyelashes or eyebrows can be a sign of many different health problems and needs a careful approach to treat effectively.
26 citations
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July 2019 in “Dermatology and Therapy” The conclusion is that genetic testing is important for diagnosing and treating various genetic hair disorders.
126 citations
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January 1987 in “Journal of The American Academy of Dermatology” The document concludes that understanding hair structure is key to diagnosing hair abnormalities and recommends gentle hair care for management.
