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The document concludes that side effects from Smoothened inhibitor drugs for skin cancer are reversible and can be managed with a team approach to maintain quality of life.

Understanding and managing side effects of hedgehog pathway inhibitors can improve treatment for advanced basal cell carcinoma.

Overexpressing Merkel cell virus proteins in human hair follicles can create clusters of cells that resemble Merkel cell cancer.

High lactate dehydrogenase activity is not necessary for the growth of squamous cell carcinoma.

Aggressive scalp squamous cell carcinomas have a high death rate and need early, strong treatment.

The study found that analyzing certain cell signaling pathways is not a reliable method to tell apart two types of skin tumors.

External factors can cause skin cancer cells that usually don't spread to grow and form tumors in mice.

Lower SMAD2/3 activation predicts more severe skin cancer.

A man with a rare scalp cancer was successfully treated, highlighting the need for early management to prevent spread and complications.

GLI1 might protect against the start of skin cancer and is not linked to cancer severity.

Skin cancer often starts from Lgr5+ progenitor cells.

Skin cancer in sun-exposed areas is more likely to come back.

Older patients with advanced kidney cancer can be managed with a drug called Sunitinib.

The cat had a rare condition linked to cancer, leading to its euthanasia.

Topical imiquimod is as effective as 5-fluorouracil for treating actinic keratosis, with about a 5% risk of it turning into squamous cell carcinoma.

The research suggests new treatments for skin cancer could target specific cell growth pathways.

LDE225 is a promising skin-applied treatment for basal cell carcinoma with good skin penetration and effectiveness.

Human dermal fibroblasts are the main cells targeted by a virus that can cause a deadly skin cancer, and a certain inhibitor can effectively block this infection.

Older adults have a high rate of skin cancers like basal cell carcinoma and melanoma, mainly due to UV exposure and age.

LGR5 and LGR6 are expressed differently in various skin tumors, which may offer clues about their origins.

Mohs micrographic surgery is effective for early-stage non-melanoma skin cancers on the lips, with basal cell carcinoma more common on the upper cutaneous lip and squamous cell carcinoma more common on the lower vermilion lip.

Men are more likely to have larger basal cell carcinomas and squamous cell carcinomas, while women have more superficial basal cell carcinomas and tumors on their legs and central face.

CD4+ skin cells may be precursors to basal cell carcinoma.

Topical patidegib gel effectively treats basal cell carcinoma in Gorlin syndrome patients without causing the side effects seen with oral treatments.

Most skin tumors in the study were benign, with squamous cell carcinoma being the most common malignant type.

Some aggressive scalp cancers are hard to treat and can be deadly, even when removed with specialized surgery.

Inactive hair follicle stem cells help prevent skin cancer.

The author now believes tricholemmal carcinoma is a rare type of infundibular squamous cell carcinoma and more research is needed on these tumors.

The protein folliculin, involved in a rare disease, works with another protein to control how cells stick together and their organization, and changes in this interaction can lead to disease symptoms.