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17α-estradiol is a safe estrogen that might protect the brain and doesn't cause feminization, needing more research for treating brain diseases.

MSC-protein helps regenerate gum tissue and bone.

Hair follicles affect how well small molecules can pass through the skin, and this varies depending on the molecule's features.

Skin aging is largely due to differences in stiffness and elasticity between skin layers, leading to wrinkles.

Mirtazapine may cause hair loss and change hair color, but stopping the drug can reverse these effects.

Wound dressing absorbs fluid, regenerates hair follicles, and heals skin burns.

The best method for transplanting skin cells to regenerate hair follicles is the Hemi-vascularized sandwich method, as it produces more mature follicles and promotes hair growth.

Myc activation reduces skin stem cells by affecting cell adhesion.

Deep dermal tissue dislocation injury in pigs leads to thicker fibrotic tissue and increased type III collagen, affecting skin repair.

Albert M. Kligman made major contributions to dermatology, including inventing a stain for fungi and advancing knowledge on skin diseases, and his legacy continues through his trainees and philanthropy.

A patient produced cortisol after adrenalectomy, possibly due to residual tissue or other body parts making steroids.

Zinc/silicon-infused hydrogel helps regenerate hair follicles.

Taking too much biotin can mess up blood test results, which might lead to wrong diagnoses and treatments.

Increased Toll-like receptors in blood cells may contribute to alopecia areata and could be a target for new treatments.

Phosphatidic acid may help hair grow by affecting cell growth pathways.

Cold atmospheric plasma may speed up wound healing and control infections.

Androgens and SARMs play a role in body mass, frailty, skin health, and hair growth, and are used in treating prostate cancer, acne, and hair loss, with potential for new uses and improved versions in the future.

High CRP levels could indicate vitamin D deficiency in people with alopecia areata.

Mice with human fetal thymic tissue and stem cells developed symptoms similar to chronic graft-versus-host disease.

Cystatin M/E strongly inhibits cathepsin V and cathepsin L, important for skin formation.

Biotin is important for health, but taking extra usually doesn't help unless you're deficient.

Eating a high-glycemic diet may worsen acne by increasing certain protein levels and expressions in the skin.

Immune cells are essential for early hair and skin development and healing.

Procyanidin compounds from apples and barley promote hair growth and prevent hair cell death.

A patch made from human lung fibroblast material helps heal skin wounds effectively, including diabetic ulcers.

Electromagnetic energy from wound dressing paste can disrupt skin lipid droplets, possibly affecting cancer development.

The document concludes that while significant progress has been made in understanding skin biology and stem cells, more research is needed to fully understand their interactions with their environment.

Stress and emotional factors can worsen skin conditions by affecting the immune system.

Blocking YAP/TAZ could be a new way to treat skin cancer.

The boy's severe skin disorder is caused by two new mutations in his TGM1 gene.