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This study found that pulsed diode laser treatment safely and effectively cleared lesions and reduced the appearance of dark plugs in trichostasis spinulosa for up to 20 weeks in dark-skinned individuals.

This study suggests that the structural integrity and physical proximity of Whn's DNA binding and activation domains are crucial for hair keratin gene activation and may explain the nude phenotype.

This study found that deleting the FoxN1 gene in mice disrupted the 3D thymic epithelial structure and led to 2D epithelial cysts, revealing its crucial role in thymus organization but not causing athymia.

This study suggests that increased putrescine levels may disrupt normal hair follicle development in transgenic mice, leading to hair loss and altered skin structure, yet these mice appear more resistant to skin tumorigenesis.

This study found that using 3D total body imaging with convolution neural networks accurately identifies risk phenotypes for melanoma, suggesting improved objective stratification for early detection and prevention.

This study suggests that yellow and white dot signs may be new dermoscopic indicators of advanced androgenetic alopecia in dark-skinned females, with certain trichoscopic features associated with darker skin types.

This study found that deleting FoxN1 in specific thymic epithelial cells disrupted the 3D thymic structure and led to age-dependent formation of 2D epithelial cysts, highlighting FoxN1's critical role in thymic morphogenesis.

This study found that the systemic wrinkled skin phenotype in Xiang pigs involves gene expression changes and genetic variations associated with oxidative stress and extracellular matrix components, resembling features seen in Shar-Pei dogs.

This thesis analyzed four skin aging features and their relationships with lifestyle, physiological factors, and genetics.

This study found a high concordance between subject-reported and clinician-reported Fitzpatrick Skin Phototypes, but 14% of subjects misjudged their skin type, often overestimating it.

This study identified a large deletion in the desmoglein 4 gene as the genetic basis of the Iffa Credo "hairless" rat's skin phenotype, linking it to lanceolate hair mutations.

Stem cells are in deep skin layers, while differentiating cells are in shallow layers.

In this multicenter study, belimumab effectively reduced disease activity in systemic lupus erythematosus patients with joint and skin manifestations, showing significant improvement in acute and subacute skin types earlier than in chronic types, while no significant benefit was observed for nonspecific skin manifestations.

Sca-1+ cells in newborn mouse skin may become fat cells.

This study concluded that extracts from fermented pumpkin peel and pulp, processed with Lactobacillus strains and kombucha, may serve as multifunctional cosmetic ingredients, offering antioxidant protection, anti-aging, and skin regeneration benefits by demonstrating cytoprotective effects and reducing inflammatory cytokines in cell assays.

This pilot study found that night shift workers showed fewer signs of wrinkle formation compared to day workers, but there were no significant differences in DNA amplification or collagen percentage.

This study found that dermal sheath stem cell characteristics are lost with aging in humans, affecting skin rejuvenation and structure, and identified specific proteins like Activin A influencing keratinocyte and fibroblast activity.

This study found that high levels of human cytokeratin 16 expression in transgenic mice lead to skin lesions and altered keratinocyte structure, suggesting potential implications for human skin disorders and wound healing.

Hedgehog signaling helps keep hair follicle stem cells the same in both young and old human skin.

This study observes that TYK2 inhibition with BMS-986202 may extend hair follicle growth phases and decrease inflammatory cell markers in alopecia areata, suggesting potential for clinical application.

This study found that repetitive 532 nm laser therapy significantly decreased scores for macules, pigmented, and vascular lesions on the facial area, regardless of skin phototype or age.

The document concludes that dermatology training and grading scales need to better represent dark-skinned individuals to improve diagnosis and assessment of skin conditions.

This review explores the role of Foxn1 in mammalian skin biology, discussing its influence on hair follicle function and the potential for further research to enhance understanding of epithelial differentiation.

This study found that exogenous EGF inhibited hair follicle development and decreased follicle density in both Tabby and normal mice, suggesting interactions between EGF and the Ta peptide influence normal skin phenotype.

Developing human skin has immune cells with memory-like features.

Scientists turned rat thymus cells into stem cells that can help repair skin and hair.

This review discusses the effects of vacuum massage on skin structures and concludes that there is insufficient evidence for its efficacy in treating burn scars, suggesting more research is needed on its potential benefits and mechanisms.

This study found that basal keratinocytes in engineered skin substitutes showed a proliferative phenotype and potential for long-term replication, which may enhance wound healing stability.

In this study, exosome-loaded hydrogels derived from skin precursor cells significantly improved wound healing in diabetic rats by enhancing angiogenesis, reducing inflammation, and promoting tissue repair.

This study highlights that ZNF750, a zinc-finger transcription factor, is crucial for epidermal differentiation and barrier formation in skin by activating genes involved in lipid processing and stratum corneum development, and links ZNF750 sequence variations to skin inflammatory diseases like psoriasis.