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This opinion article explores the possibility of repurposing anticancer drugs, like methotrexate, as antimalarials, highlighting that toxicity might be manageable with appropriate dosing according to Paracelsus' law.

This study reviewed the pharmacological properties of fesoterodine and found that its ability to effectively treat overactive bladder, especially in the elderly, is likely due to its specific properties, including its receptor affinity, blood-brain barrier penetration, metabolic conversion, and extended-release formulation.

In this pilot study, no significant differences were observed between memantine and placebo groups in young adults with Down syndrome on the primary memory outcomes, but some improvement was noted in a secondary measure.

This abstract lists keywords related to various medications and therapies, but it does not provide new study results or findings.

This study found that dual ASM therapies involving valproic acid were associated with poorer tolerability and specific adverse events, with cognitive side effects occurring prominently across all examined combinations.

This review provides an overview of the prevalence and management of side effects of mood-stabilizing drugs in bipolar disorder patients and reports no new clinical results.

Finasteride significantly reduced tics and obsessive-compulsive symptoms in patients with Tourette syndrome.

This case study provides an exemplar of a 75-year-old man with metastatic renal cell carcinoma, outlining his medical history, recent imaging findings, and treatment decisions; it reports no clinical results.

This review outlines strategies for preventing, identifying, and managing complications related to current MS therapies and reports no new clinical results, emphasizing the growing complexity in MS treatment regimens.

This study demonstrated that certain metal salts can bind to sodium valproate and discussed the potential link to hair loss in patients treated for epilepsy.

This case report found that the most likely cause of the patient's seizures and brain tumor was prior radiation exposure, with seizures managed effectively using intravenous lorazepam and subsequent treatment for the brain mass.

This study found that Cinobufacin combined with chemotherapy improved clinical outcomes in breast cancer patients and reduced certain side effects compared to chemotherapy alone.

This study found that cromakalim and pinacidil significantly inhibited porcine detrusor muscle contractions, suggesting these ATP-sensitive potassium channel openers may have potential in treating certain bladder diseases.

This study found that SER120 nasal spray significantly improved nocturia symptoms and quality of life compared to placebo in patients 50 years and older, with both tested doses showing efficacy and an acceptable safety profile over a 12-week period.

This article compares cabergoline and bromocriptine for treating hyperprolactinemic amenorrhea and reports no specific findings.

This review discusses the mechanisms, uses, and side effects of conventional synthetic DMARDs, particularly methotrexate, for rheumatoid arthritis, but reports no new clinical findings.

This article provides no abstract or new findings and focuses on a patient registry related to spasticity care.

Different medications can cause serious side effects in some people.

This study reported the development of new pyrazole-based MPC inhibitors that effectively inhibit mitochondrial pyruvate transport, showing potential as therapeutic candidates for conditions like metabolic dysfunction-associated steatohepatitis without activating PPARγ.

This review discusses the guidelines for using and monitoring mood stabilizers in bipolar disorders, highlighting that only a minority of patients receive guideline-adherent monitoring.

This communication reports previously unreported side effects, severe bullous dermatosis and onycholysis, in three patients undergoing high-dose methotrexate and leucovorin calcium therapy, impacting their chemotherapy schedules.

This report describes a case of a patient with Sjogren's syndrome who experienced multiple episodes of aseptic meningitis linked to taking trimethoprim-sulfamethoxazole and trimethoprim alone.

The LRRK2-G2019S mutation in Parkinson's disease has a lifetime penetrance of 25-35%, and finasteride may help reduce symptoms in adult male Tourette syndrome patients.

Some medications caused temporary health issues that improved after stopping the drugs, but two patients died from liver problems linked to carbamazepine.

This study concluded that while methotrexate-related adverse events were infrequent in early rheumatoid arthritis patients taking adalimumab, some increased with higher methotrexate doses, suggesting use of the lowest effective dose.

This study observed that among Iranian patients with rheumatoid arthritis, methotrexate treatment was discontinued or reduced in nearly half of the cases due to side effects such as nausea, flu-like symptoms, hepatotoxicity, and hair loss, with hepatotoxicity linked to higher doses and longer treatment duration.

This study found that sodium valproate improved seizure control in children with epilepsy, with increased weight gain being the most common side effect reported.