152 citations,
March 1988 in “Journal of The American Academy of Dermatology” Superficial granulomatous pyoderma is a unique, mild form of skin disease that often heals without strong medication and responds well to milder treatments.
152 citations,
December 2007 in “Gender Medicine” Male and female skin differ due to hormones, affecting conditions like hair loss, acne, and skin cancer, and suggesting a need for gender-specific treatments.
151 citations,
November 2018 in “International Journal of Pharmaceutics” Nanoparticles improve drug delivery through the skin but more research is needed on their long-term effects and skin penetration challenges.
151 citations,
February 2007 in “International Journal of Dermatology” Alopecia areata causes hair loss, has no cure, and various treatments exist.
151 citations,
December 2004 in “Annals of the New York Academy of Sciences” Congenital Adrenal Hyperplasia is a genetic disorder with two forms, causing symptoms like early puberty and severe acne, but can be identified through screening and treated with glucocorticoids.
150 citations,
June 2014 in “Biomaterials” Peptide hydrogels heal burn wounds faster and better than standard dressings.
148 citations,
April 2009 in “Molecular Pharmaceutics” Researchers developed promising agents for prostate cancer imaging, with the best one showing high potential for clinical use.
147 citations,
June 2011 in “New England journal of medicine/The New England journal of medicine” 5α-reductase inhibitors may prevent prostate cancer but could also raise the risk of more severe cancers.
147 citations,
January 2003 in “American journal of clinical dermatology” The document concludes that accurate diagnosis of ichthyosis is crucial for treatment and genetic advice, and ongoing research is needed for better therapies.
145 citations,
November 2018 in “Nature Communications” The Sonic hedgehog pathway is crucial for new hair growth during mouse skin healing.
144 citations,
August 2019 in “Cells” The WNT signaling pathway is important in many diseases and targeting it could offer new treatments.
143 citations,
October 1996 in “Dermatologic Clinics” Too much androgen can cause hair loss; finasteride may help.
142 citations,
January 2019 in “Frontiers in Neuroendocrinology” Postpartum depression is linked to changes in brain chemicals, inflammation, stress, and certain genes, and can potentially be identified by markers like specific steroids, serotonin levels, and vitamin D levels.
142 citations,
March 2019 in “Frontiers in Cellular Neuroscience” The document concludes that adenosine receptor agonists have potential for treating various conditions, but only a few are approved due to challenges like side effects and the need for selective activation.
141 citations,
November 2005 in “International journal of pharmaceutics” Hair follicles may soon be used more for targeted and systemic drug delivery.
139 citations,
February 2014 in “Journal of Advanced Research” Vitamin D is important for skin health and may affect conditions like psoriasis and hair loss, but more research is needed to understand its role fully.
139 citations,
October 1999 in “Environmental Health Perspectives” Modern science supports the use of some Ayurvedic plants for health, as ancient practices suggested.
138 citations,
July 2015 in “Clinical, Cosmetic and Investigational Dermatology” Eating less sugar, milk, and saturated fats and more vegetables and fish may help treat and prevent acne.
137 citations,
March 2006 in “Cns Drug Reviews” Finasteride treats enlarged prostate and hair loss, but may cause side effects in some patients.
136 citations,
May 2016 in “Phytotherapy Research” Turmeric may have benefits for skin health, but more research is needed to confirm its effectiveness.
130 citations,
January 1994 in “Differentiation” Mouse hair follicle cells briefly grow during the early hair growth phase, showing that these cells are important for starting the hair cycle.
130 citations,
August 2020 in “Drug Design Development and Therapy” Nanoparticles can improve skin drug delivery but have challenges like toxicity and stability that need more research.
129 citations,
January 2019 in “Clinical medicine insights” Obesity worsens PCOS symptoms, and PCOS may lead to more weight gain; managing both requires a holistic approach that includes mental health.
129 citations,
November 2005 in “Internal Medicine Journal” Early detection and intensive treatment of diseases caused by Staphylococcus aureus toxins are crucial for reducing severe health effects.
127 citations,
January 2015 in “Journal of Biological Rhythms” The skin's internal clock affects healing, cancer risk, aging, immunity, and hair growth, and disruptions can harm skin health.
126 citations,
October 1983 in “Journal of The American Academy of Dermatology” Isotretinoin effectively treats severe acne and similar conditions, but has common, mostly reversible side effects, requiring careful patient monitoring.
126 citations,
January 1987 in “Journal of The American Academy of Dermatology” The document concludes that understanding hair structure is key to diagnosing hair abnormalities and recommends gentle hair care for management.
125 citations,
January 1999 in “Drugs” Finasteride effectively treats baldness but may cause sexual side effects.
125 citations,
September 2019 in “Journal of Clinical Immunology” Foxp3 is crucial for regulatory T cell function, and targeting these cells may help treat immune disorders.
124 citations,
June 2020 in “Cell Stem Cell” Fat cells in the skin help start healing and form important repair cells after injury.