Updates in Therapeutics for Pediatric Alopecia Areata: A Systematic Review with Evidence-Based Analysis

    April 2019 in “ ˜The œjournal of investigative dermatology/Journal of investigative dermatology ”
    Pooja H. Rambhia, Raghav Tripathi, Rosalynn R.Z. Conic, Aizuri Murad, Natasha Atanaskova Mesinkovska, Melissa Piliang, Wilma F. Bergfeld
    Image of study
    TLDR High potency topical steroids are the most effective treatment for pediatric alopecia areata.
    This systematic review analyzed 23 studies involving 250 pediatric patients with alopecia areata (AA) to evaluate current treatments. The highest level of evidence (Grade 2) supported the efficacy of high potency topical steroids and 1% anthralin ointment, with significant hair regrowth and no additional side effects. Other treatments examined included the 308-nm excimer laser, zinc aspartate, biotin, clobetasol propionate, tofacitinib, methotrexate, and more, but these had lower levels of evidence (Grades 3 and 4). The review concluded that high potency topical steroids were the most effective, but larger clinical trials are needed to explore newer treatments for pediatric AA.
    Discuss this study in the Community →

    Related Community Posts Join

    6 / 1000+ results

      community Rare Non responder to Finasteride, Dutasteride, and oral minoxidil

      in Minoxidil  78 upvotes 9 months ago
      A user did not respond to finasteride, dutasteride, and oral minoxidil for hair loss after four years of treatment and is considering scalp micropigmentation (SMP). Other users suggest the hair loss pattern may indicate alopecia areata and recommend seeing a dermatologist.

      community 7 Month Hair Progress (0.5 mg dut only, diffuse thinning)

      in Progress Pictures  711 upvotes 9 months ago
      An 18-year-old male switched from topical finasteride and minoxidil to oral dutasteride for diffuse hair loss and saw improvement without side effects, despite experiencing scalp itch and shedding. Commenters noted significant hair regrowth and were surprised by his young age and appearance.

      community It's over. Hairline has fallen. Millions must shave.

      in Update  467 upvotes 1 year ago
      The conclusion of the conversation is that the user has tried various medications and treatments for hair loss, including minoxidil, finasteride, microneedling, and nizoral shampoo, but has not seen any progress. They have decided to shave their head. Other users suggest options such as hair transplants, RU58841, hair units, and scalp micropigmentation.

      community any news about DUPA (Diffuse unpatterned alopecia)?

      in Research/Science  9 upvotes 2 years ago
      The conversation discusses diffuse unpatterned alopecia (DUPA) and its possible causes, including sensitivity to DHT, not being androgenic alopecia, being diffuse alopecia areata, or hormonal issues. Treatments mentioned include topical melatonin, Clobetasol Propionate for alopecia areata, and the lack of results from using finasteride, dutasteride, and minoxidil.

      community 10 months CB and Oral Minoxidil

      in Progress Pictures  110 upvotes 8 months ago
      A person with Alopecia Areata on their beard is using CB-03-01 and oral minoxidil for treatment. Some users question the effectiveness of CB-03-01 for beard hair, suggesting that minoxidil alone may be responsible for any observed hair growth.

      community *WOMEN* on Spironolactone - experiences?

       6 upvotes 9 years ago
      Hair loss treatments discussed: Minoxidil, Finasteride, RU58841, and Spironolactone. Woman with androgenetic alopecia and alopecia areata shares experience using Spironolactone.

    Related Research

    4 / 4 results