Catagen in the Hairless House Mouse
November 1967
in “
American Journal of Anatomy
”
New to collagen? There is a guide in the encyclopedia. Read the guide → Studysummary This study observed that the catagen phase in hairless mice displayed a slower shortening of the mutant epithelial column, resulting in longer total follicle length and abnormalities in the connective tissue sheath and glassy membrane.
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The study focused on the catagen phase of the first hair cycle in hairless (hr) mice, examining morphological and histochemical aspects. Key findings included that the mutant epithelial column shortened at a slower rate, resulting in a greater total follicle length at catagen VII, while the hair shaft's position remained normal. The keratinization sequence of the mutant club appeared normal, but there was a failure to form an anchoring brush due to variations in cell shapes and fibrils. The inner root sheath extended further than normal, enclosing the club. Additionally, the glassy membrane and connective tissue sheath were abnormally narrow, primarily due to reduced collagen and a narrower band of PAS-positive material.
