research Clinical Impact of Molecular Diagnostics in Endocrinology
Molecular diagnostics help identify genetic defects causing endocrine diseases, improving diagnosis and treatment options.
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120-150 / 261 results ![Effect of C-Ring Modifications in Benzo[c]quinolizin-3-ones, New Selective Inhibitors of Human 5α-Reductase 1](/images/research/c687900f-ea40-4de1-8f0b-a5b818951b1c/small/15452.jpg)
research Effect of C-Ring Modifications in Benzo[c]quinolizin-3-ones, New Selective Inhibitors of Human 5α-Reductase 1
Changing the C-ring structure in certain compounds can make them better at blocking a specific human enzyme.
research Evaluation of New Pregnane Derivatives as 5α-Reductase Inhibitors
New pregnane derivatives are effective at inhibiting an enzyme linked to hair loss and reducing oil gland activity.
research Expression of Type 1 5α-Reductase and Metabolism of Testosterone in Reconstructed Human Epidermis: A New Model for Screening Skin-Targeted Androgen Modulators
The study created a new method to test drugs that affect hormone processing in skin.
research Microneedles Mediated Bioinspired Lipid Nanocarriers for Targeted Treatment of Alopecia
A new hair loss treatment uses tiny needles to deliver a drug-loaded lipid carrier, promoting hair growth more effectively than current treatments.
research Traditional Uses, Phytochemistry, Pharmacology, Toxicity and Clinical Application of Traditional Chinese Medicine Cynoglossum Amabile: A Review
Cynoglossum amabile has medicinal potential but poses safety concerns due to liver toxicity.
![Synthesis and In Vitro Study of 17β-[N-Ureylene-N,N′-Disubstituted]-4-Methyl-4-Aza-5α-Androstan-3-Ones as Selective Inhibitors of Type I 5α-Reductase](/images/research/d19df8a7-8de6-4430-8a0d-4ffa1f502985/small/15608.jpg)
research Synthesis and In Vitro Study of 17β-[N-Ureylene-N,N′-Disubstituted]-4-Methyl-4-Aza-5α-Androstan-3-Ones as Selective Inhibitors of Type I 5α-Reductase
New compounds were made that effectively block a specific enzyme related to androgen conditions.
research Ovine Placental Steroid Synthesis and Metabolism in Late Gestation
Diet changes hormone levels in pregnant ewes by affecting metabolism, not placental synthesis.
research Properties and Applications of Nanoparticles and Nanomaterials
Nanoparticles have diverse applications, including promising cancer treatments and hair growth solutions.
research Nutraceutical and Functional Scenario of Wheat Straw
Wheat straw is valuable for its health benefits and various industrial uses.
research Chitosan Hydrogel as Tissue Engineering Scaffolds for Vascular Regeneration Applications
Chitosan hydrogels are promising for repairing blood vessels but need improvements in strength and compatibility.
research Wound Treatment Using Nanomaterials
Nanomaterials like silver and gold can improve wound healing but need more research for safety.
research Recent Advances in Genome-Editing Technology with CRISPR/Cas9 Variants and Stimuli-Responsive Targeting Approaches within Tumor Cells: A Future Perspective of Cancer Management
New CRISPR/Cas9 variants and nanotechnology-based delivery methods are improving cancer treatment, but choosing the best variant and overcoming certain limitations remain challenges.
research Inhaled Medicines for Targeting Non-Small Cell Lung Cancer
Inhaling medicine may reduce side effects and improve treatment for a major lung cancer type.
research Advanced Polymer Hydrogels That Promote Diabetic Ulcer Healing: Mechanisms, Classifications, and Medical Applications
Special gels help heal diabetic foot sores and reduce the risk of amputation or death.
research Carbon Dots With Tissue Engineering and Regenerative Medicine Applications
Carbon dots show promise for tissue repair and growth but need more research to solve current challenges.
research References
research Current Insight of Peptide-Based Hydrogels for Chronic Wound Healing Applications: A Concise Review
Peptide-based hydrogels are promising for healing chronic wounds effectively.
research Nanomaterials Applied in Wound Healing: Mechanisms, Limitations, and Perspectives
Nanomaterials can significantly improve wound healing and future treatments may include smart, real-time monitoring.
research Potential Use of Human Hair Fibers for Reinforcement and Thermal Insulation in Construction
Adding human hair to cement can make it tougher and better insulated but also more porous.
research Liposome-Based Carriers for CRISPR Genome Editing
Liposomes show promise for delivering CRISPR for gene editing but face challenges like delivery efficiency and safety concerns.
research Proteins in Scalp Hair of Preschool Children
Hair proteins in preschool children and their mothers could indicate developmental changes and health status.
research In Silico Study of 12 Phytosterol Compounds in Moringa (Moringa Oleifera Lamk.) Seed Oil on 5α-Reductase Enzyme Inhibition Activity as Anti-Alopecia
Ergostadienol from Moringa seed oil may help prevent hair loss.
research In Silico Prediction of Prostaglandin D2 Synthase Inhibitors from Herbal Constituents for the Treatment of Hair Loss
Herbal compounds like ricinoleic acid, quercetin-3-O-rutinoside, and hinokiflavone may be safe and effective for treating hair loss.
research Survey of Dermoscopy Use by Taiwanese Dermatologists
About half of Taiwanese dermatologists use dermoscopy, mainly to improve diagnosis and detect cancer early, but cost and lack of training limit its wider use.
research In Silico Structural Prediction of Human Steroid 5α-Reductase Type II
Scientists found out the structure of a human enzyme linked to prostate cancer and hair loss, which could help in designing drugs.
research Drug Repositioning Using In Silico Compound Profiling
Using computers to analyze drugs can find new uses for them, but actual experiments are needed to confirm these uses.
research Evaluating Hair Growth Promoting Effects of Candidate Substances: A Review of Research Methods
The document concludes that while lab results for hair growth promotion are promising, human trials are needed and better testing methods should be developed.
research Lipedematous Alopecia with Mucinosis: Report of the First Case in Taiwan
Taiwan reported its first case of a rare scalp condition with no clear cause or treatment.
research Upadacitinib for the Treatment of Alopecia Areata – A Case Report
Upadacitinib helped regrow hair in a severe alopecia areata patient but stopping treatment caused hair loss to return.