34 citations
,
October 2014 in “European journal of pharmaceutics and biopharmaceutics” This study found that adapalene-loaded solid lipid microparticles may enhance targeted drug delivery into sebum due to their similarity to sebum components, although both this formulation and a standard cream showed equivalent follicular penetration.
34 citations
,
October 2011 in “Pathology Research International” This article reviews potential factors influencing Behçet's disease, like increased neutrophil functions, immunological changes, stress, and hormonal alterations, but it presents no new clinical results.
34 citations
,
January 2008 in “International Review of Neurobiology” This review discusses the interplay between epilepsy and reproductive endocrine disorders, examining the factors involved and emphasizing the importance of monitoring but reports no new research findings.
34 citations
,
October 1982 in “Journal of applied polymer science” This study found that the moisture content of human hair significantly influences the type of fracture under tensile loading, with low or high humidity levels leading to smooth fractures and intermediate humidity resulting in step fractures.
33 citations
,
September 2016 in “Lasers in Surgery and Medicine” In this review, the authors report that fractional resurfacing can be a safe and effective technique for treating scars and promoting photorejuvenation in Asian skin, though it requires cautious use to minimize risks like post-inflammatory hyperpigmentation and rebound melasma.
33 citations
,
September 2012 in “Wound Repair and Regeneration” This study found that the application of calreticulin significantly improved wound healing time and quality in diabetic mice, suggesting it may be an effective topical treatment for chronic wounds.
32 citations
,
February 2019 in “Journal of neurochemistry” This study found that pharmacological inhibition of sex steroid synthesis impacts pathogenic processes in traumatic brain injury in a sex-specific manner, with distinct effects of letrozole and finasteride on molecular and neurological outcomes.
31 citations
,
June 2022 in “Journal of Yeungnam Medical Science” This review discusses the use of platelet-rich plasma for musculoskeletal pain relief and function improvement, but notes the current studies' limitations regarding methods and types of treatment.
31 citations
,
April 2019 in “Experimental and Therapeutic Medicine” This review focuses on the immunologic-based skin conditions that can result from β-blocker use, emphasizing potential adverse dermatologic effects rather than their therapeutic benefits.
31 citations
,
February 2019 in “International Journal of Cosmetic Science” This study found that ultraviolet radiation negatively affects hair follicle functions in human scalp skin, and caffeine application may provide some protective effects against this damage.
31 citations
,
June 2018 in “Dermatologic Surgery” In this randomized, double-blind trial, researchers observed that low-level laser therapy led to significantly greater hair regrowth on treated areas compared to a sham treatment in patients with androgenetic alopecia over 24 weeks, suggesting it as a potentially effective and safe option.
31 citations
,
July 2017 in “Clinical Science” This review discusses the role of microRNAs in skin function and potential therapeutic applications, emphasizing their importance in wound healing and disease management, though it reports no new experimental findings.
31 citations
,
January 2017 in “Phytotherapy Research” This review reports on the traditional and ethnopharmacological uses of Ziziphus jujuba Mills, noting its increasing global popularity for treating various ailments, but highlights that its acceptance into the European Pharmacopoeia remains unresolved due to scientific and regulatory challenges.
31 citations
,
March 2009 in “Archives of Facial Plastic Surgery” This retrospective study found that a hairline-lowering technique effectively advanced the female hairline by an average of 2.1 cm with high patient satisfaction and minimal complications over 20 years.
31 citations
,
July 2004 in “Molecular Medicine” This study found that mutant glucocorticoid receptors have defective transcriptional activity and dynamic motility issues in the nucleus, likely due to impaired interactions with nuclear molecules necessary for gene activation.
31 citations
,
October 2002 in “Dermatologic Surgery” This article reviews expert opinions on combining pharmacologic treatments like minoxidil with hair transplantation, reporting improved hair density and regrowth in patients with partially functioning follicles.
31 citations
,
April 1999 in “Dermatologic Clinics” This article reviews the use of the Nd:YAG laser for hair removal and reports no new research findings.
30 citations
,
April 2021 in “The Journal of Sexual Medicine” This guideline provides recommendations for prescribing systemic testosterone to women with hypoactive sexual desire disorder, emphasizing safe dosing, monitoring, and the need for informed consent despite regulatory challenges.
30 citations
,
November 2008 in “Facial Plastic Surgery” This review discusses hair transplant techniques for female pattern hair loss and reports no new clinical results; it highlights the benefits of transplants combined with various treatments for improved hair density and styling options.
29 citations
,
September 2012 in “Dermatologic Clinics” This article reviews the causal mechanisms of hair follicle disorders, focusing on inflammation, genetics, environment, and hormones, but it reports no new clinical results.
29 citations
,
January 2010 in “Methods in Enzymology” This review discusses five genetic fate mapping methods used to study cell behaviors during development and regeneration, detailing the necessary tools and considerations without reporting new experimental results.
29 citations
,
January 2007 in “American Journal of Clinical Dermatology” This article reviews the social and functional impact of eyebrow loss and highlights the limited treatment options compared to scalp alopecia, but reports no new clinical results.
28 citations
,
October 2019 in “Seminars in Cell & Developmental Biology” This article discusses the advances in understanding wound-induced hair follicle neogenesis (WIHN) and highlights the roles of specific signaling pathways and cellular plasticity, noting no clinical results but suggesting potential areas for further research.
28 citations
,
January 2016 in “Vitamins and hormones” This source reports that thymosin beta 4 accelerated dermal wound repair in phase 2 clinical trials for pressure ulcers, stasis ulcers, and epidermolysis bullosa wounds and was well tolerated.
28 citations
,
September 2015 in “Wiener Klinische Wochenschrift” New skin substitutes for treating severe burns and chronic wounds are being developed, but a permanent solution for deep wounds is not yet available commercially.
28 citations
,
September 2008 in “Current Pharmaceutical Design” This review discusses hypersensitivity reactions to anticoagulants like ASA and heparins, highlighting their rare but potentially life-threatening nature, and emphasizes the need for meticulous allergy testing to find safe alternatives.
28 citations
,
December 2006 in “Clinical lung cancer” This review outlines various non-rash skin toxicities associated with novel targeted anticancer therapies and provides guidelines for their early diagnosis and management, but reports no new clinical results.
27 citations
,
April 2018 in “Scientific Reports” This study found that in psoriasis patients, the K17 protein probably functions as an autoantigen, with the HLA-Cw*06:02 risk genotype strongly linked to the T cell response size.
27 citations
,
July 2017 in “Scientific Reports” This study found that conditional knockout of N-WASP in keratinocytes of mice led to skin barrier defects, increased immune cell infiltration, and hyperproliferation of keratinocytes, indicating its crucial role in skin homeostasis.
27 citations
,
June 2015 in “Revista Brasileira de Farmacognosia” This review discusses the traditional uses, pharmacology, clinical applications, and toxicology of Carthami flos but reports no new clinical results, aiming to inform further research on its medicinal potential.