research From In-Vitro to In-Vivo: Corporate Development and Efficacy of a Topical Hair Growth Agent Derived from Natural Extracts
A natural extract-based hair growth product was developed and showed promise in preliminary tests.
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research Perilla Frutescens: A Rich Source of Pharmacologically Active Compounds
Perilla frutescens, an East Asian plant, contains 400 bioactive compounds that have various health benefits, including anti-inflammatory, antidepressant, and anticancer effects, and can treat conditions like diabetes, skin allergies, and neurological disorders.
research Small Molecules Accelerate Skin Wound Healing: Shikonin Efficacy and Mechanism of Action in Mice
Shikonin, a small molecule, speeds up skin wound healing in mice.
research Bioactive Small Molecule Enhances Skin Burn Wound Healing and Hair Follicle Regeneration by Activating PI3K/AKT Signaling Pathway: A Preclinical Evaluation in Animal Model
Shikonin, a small molecule, speeds up burn wound healing and hair growth by activating the PI3K/Akt pathway.
research Woolly Antics Between the Sheaths
Lipase H is important for hair follicle function and shaping hair fibers.
research Editors' Picks
Scientists found gene mutations that affect hair loss, skin stem cells, and skin disorders, and identified drugs that may help treat blood vessel and skin conditions.
research The Functional Organization of Cutaneous Low-Threshold Mechanosensory Neurons
Different hair follicles in the skin are innervated by unique combinations of mechanosensory neurons, crucial for touch sensation.
research Noninvasive Method for Assessing the Human Circadian Clock Using Hair Follicle Cells
Scientists found a new, less invasive way to study body clocks using hair cells, which shows shift workers' body clocks don't match their lifestyles.
research The IL-23/IL-17 Pathway in Inflammatory Skin Diseases: From Bench to Bedside
Targeting the IL-23/IL-17 pathway effectively treats several inflammatory skin diseases.
research RBPJ Mutations Identified in Two Families Affected by Adams-Oliver Syndrome
Mutations in the RBPJ gene cause Adams-Oliver Syndrome.
research PH Sensitive Nano Layered Double Hydroxides Reduce the Hematotoxicity and Enhance the Anticancer Efficacy of Etoposide on Non-Small Cell Lung Cancer
The nano-carrier makes etoposide safer and more effective against lung cancer.
research Cortical Cell Types and Intermediate Filament Arrangements Correlate with Fiber Curvature in Japanese Human Hair
Hair curvature in Japanese people is linked to specific cell types and filament arrangements in the hair cortex.
research Exosomes Mediate Sensory Hair Cell Protection in the Inner Ear
Exosomes are crucial for protecting sensory hair cells in the inner ear.
research Mice Engrafted with Human Fetal Thymic Tissue and Hematopoietic Stem Cells Develop Pathology Resembling Chronic Graft-Versus-Host Disease
Mice with human fetal thymic tissue and stem cells developed symptoms similar to chronic graft-versus-host disease.
research Intrinsic Curvature in Wool Fibres Is Determined by the Relative Length of Orthocortical and Paracortical Cells
Wool fibre curvature is due to longer orthocortical cells compared to paracortical cells.
research Changes in Structure and Geometric Properties of Human Hair by Aging
Older people's hair becomes less shiny because it gets more uneven and curved.
research Epidemiology of Post-COVID Conditions Beyond 1 Year: A Cross-Sectional Study
Over 25% of COVID-19 patients had symptoms lasting more than a year.
research Characterization of Curved Hair of Japanese Women with Reference to Internal Structures and Amino Acid Composition
Japanese women's curved hair has an uneven internal structure and varying amino acid composition.
research Chemical Mechanism of the Covalent Modification of 5-Alpha-Reductases by Finasteride as Probed by Secondary Tritium Isotope Effects
Finasteride modifies 5-alpha-reductases through a two-step process, affecting inhibitor potency and possibly causing side effects.
research Nongenomic Effects of 1α,25-Dihydroxyvitamin D3 on Cartilage Formation Deduced from Comparisons Between Cyp27b1 and Vdr Knockout Mice
1α,25-dihydroxyvitamin D3 directly affects cartilage growth and development.
research Matriptase Expression and Zymogen Activation in Human Pilosebaceous Unit
Matriptase is highly active in hair follicles and sebaceous glands, especially during hair growth phases.
research Distribution Analysis of Triglyceride Having Repair Effect on Damaged Human Hair by TOF-SIMS
Hydrogenated palm oil repairs and conditions damaged hair by preventing swelling.
research Extensive Donor Site Keloids in Follicular Unit Extraction Hair Transplantation
Hair transplant can cause hard-to-treat keloids in some patients.
research Alopecia Areata Multiplex Following Autologous Dermal Micrograft Injection for Treatment of Androgenetic Alopecia
Hair loss treatment caused more hair loss in a man.
research Stiffness of Human Hair Correlates with the Fractions of Cortical Cell Types
Hair stiffness is higher when it has more para-like cortical cells.
research Characteristic Microstructure of Curved Human Hair
Curved human hair has different structures on its convex and concave sides.
research Scalp Hair Repigmentation in the Penumbral Region of Radiotherapy: A Case Series
Radiotherapy can cause rare changes in hair color, which should be discussed with patients.
research The Secrets of Beautiful Hair: Why Is It Flexible and Elastic?
Beautiful hair is flexible and elastic due to its unique double-layered structure and can be enhanced with succinic acid treatment.
research Regulatory T Cells Influence Hair Follicle Cycle and Stem Cell Activation
Immune cells called Treg cells are essential for hair growth and regeneration.
research Three-Dimensional Adipofascial and Dermal Structures Involved in Forehead Crease Formation
Forehead creases are formed by a tight connection between the skin and muscle through dense fibers, with changes in skin thickness and fewer skin appendages near the creases.