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The Rotterdam Study found risk factors for elderly diseases, links between lifestyle and genetics with health conditions, and aimed to explore new areas like DNA methylation and sensory input effects on brain function.

Lgr5 is a marker for active, self-renewing stem cells in the intestine and skin, important for tissue maintenance.

The Rotterdam Study aims to understand disease causes in the elderly and has found new risk factors and genetic influences on various conditions.

New nanofiber technology improves wound healing by supporting cell growth and delivering treatments directly to the wound.

Wnt signaling is crucial for pigmented hair regeneration by controlling stem cell activation and differentiation.

AGA causes hair loss by shrinking hair follicles due to DHT binding, and can be treated with finasteride and minoxidil.

The document concludes that understanding hair follicle biology can lead to better hair loss treatments.

Hair follicles help absorb and store topical compounds, aiding targeted drug delivery.

Noggin is necessary to start the hair growth phase in skin after birth.

Calcium affects where root hairs grow, but other unknown factors determine their growth direction.

Skin cells produce and activate vitamin D, which regulates skin functions and supports hair growth.

Capsaicin, found in chili peppers, can slow down hair growth by affecting skin cells and hair follicles.

Wnt signaling controls whether hair follicle stem cells stay inactive or regenerate hair.

Hair follicle stem cells are key for hair and skin regeneration, can be reprogrammed, and have potential therapeutic uses, but also carry a risk of cancer.

Skin aging is due to impaired stem cell mobilization or fewer responsive stem cells.

Different types of stem cells with unique roles exist in blood, skin, and intestines, and this variety is important for tissue repair.

Prolactin contributes to hair loss by promoting hair follicle shrinkage and cell death.

The telogen phase of hair growth is active and important for preparing hair follicles for regeneration, not just a resting stage.

Understanding how cells die in the skin is important for treating skin diseases and preventing hair loss.

Asia has made significant progress in tissue engineering and regenerative medicine, but wider clinical use requires more development.

Fibroblast growth factor receptor signaling controls cell development and repair, and its malfunction can cause disorders and cancer, but it also offers potential for targeted therapies.

Macrophages help regrow hair by activating stem cells using AKT/β-catenin and TNF.

Scientists turned rat thymus cells into stem cells that can help repair skin and hair.

The document concludes that assessing hair follicle damage due to cyclophosphamide in mice involves analyzing structural changes and suggests a scoring system for standardized evaluation.

Nerves and chemicals in the body can affect hair growth and loss.

Androgens can both stimulate and cause hair loss, and understanding their effects is key to treating hair disorders.

Hormones significantly affect hair and oil gland function in the skin, and more research is needed on skin-related hormone disorders.

The document concludes that adult mammalian skin contains multiple stem cell populations with specific markers, important for understanding skin regeneration and related conditions.

The p75 neurotrophin receptor is important for hair follicle regression by controlling cell death.

Skin development in mammals is controlled by key proteins and signals from underlying cells, involving stem cells for maintenance and repair.