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Lack or blocking of SRD5a, a key component in hormone creation, can lead to conditions like pseudohermaphrodism and affect hair growth, bone mass, muscle strength, and reproductive health. More research is needed on its regulation from fertilization to adulthood.

5α-Reductase inhibitors can help treat hair loss, acne, and prostate issues by reducing DHT levels.

The document concludes that PK/PD modeling is important for determining the safe and effective dosages of drugs.

The document concludes that more research is needed to fully understand the causes of PCOS.

Hormones affect skin aging and fat distribution, and treatments can help, but only minoxidil is proven for female hair loss.

SLE patients experience two patterns of non-inflammatory symptoms: intermittent and persistent.

Acne is caused by multiple factors including oil production, bacteria, inflammation, and possibly diet and environment.

Ingesting Leucaena leucocephala caused hair loss and increased infant mortality in ringtailed lemurs.

Aging skin shows thinner layers, fewer hair follicles, and new biomarkers like increased space between cells and smaller sebaceous glands.

The document concludes that more research is needed to understand hair loss in men and to find new treatments.

About 8% of people with systemic lupus erythematosus have chronic scarring alopecia, with certain symptoms and positive antibodies increasing the risk, while immunosuppressants may lower it.

Addressing underrepresentation in Parkinson's research is crucial for better treatments and understanding.

New treatments and diagnostic methods for various animal skin conditions showed promising results.

A high-fat diet caused severe health problems in female macaques but was reversible with a normal diet, while male macaques reacted differently.

Terbinafine is the most effective medicine for fungal nail infections, especially for diabetics and those with weak immune systems.

A specific DNA sequence caused hair loss in male mice by activating immune cells and increasing a certain immune signal.

Many women experience sexual dysfunction, but few seek help, and better treatment and medical training are needed.

Autonomic dysfunction is common in hypertensives but may not cause diastolic dysfunction in resistant hypertension.

Hair follicle biology advancements may lead to better hair growth disorder treatments.

The enzyme steroid sulfatase is linked to breast cancer and other conditions, and inhibitors are being developed for treatment.

Estrogens significantly influence hair growth by interacting with receptors in hair follicles and may help regulate the hair growth cycle.

The document concludes that more research is needed to better understand and treat primary cicatricial alopecias, and suggests a possible reclassification based on molecular pathways.

Estrogens help reduce skin aging, and SERMs might offer similar benefits without the risks of hormone therapy.

Male hormones and their receptors play a key role in hair loss and skin health, with potential new treatments being explored.

The sebaceous gland has more roles than just producing sebum and contributing to acne, and new research could lead to better skin disease treatments.

The document concludes that accurate diagnosis and personalized treatment are important for skin problems in women with PCOS.

Acne is a chronic disease linked to various systemic conditions and has significant psychological and social effects.

Beta-caryophyllene helps improve wound healing in mice, especially in females.

WNT10A helps esophageal cancer cells spread and keep renewing themselves.

Hormones and their receptors, especially androgens, play a key role in hair growth and disorders like baldness.