40 citations,
June 2021 in “Clinical, cosmetic and investigational dermatology” JAK inhibitors show promise in effectively treating hair loss from alopecia areata.
9 citations,
August 2021 in “Experimental dermatology” Hidradenitis suppurativa is a skin disease caused by the breakdown of the skin's natural immune barriers, especially around hair follicles.
Enterococcus faecalis delays wound healing by disrupting cell functions and creating an anti-inflammatory environment.
January 2023 in “Indian Dermatology Online Journal” No single ideal JAK inhibitor for alopecia areata has been determined; JAK3 inhibitors may be promising with fewer side effects.
October 2017 in “Journal of Investigative Dermatology” Researchers created human cells that can turn into sebocytes, which may help study and treat skin conditions like acne.
October 2017 in “Journal of Investigative Dermatology” The study found that sweat glands normally suppress immune responses, but this is disrupted in certain skin diseases, possibly contributing to their development.
31 citations,
September 2013 in “Stem Cells” Smad1 and Smad5 are essential for hair follicle development and stem cell sleepiness.
118 citations,
August 2010 in “Developmental Cell” MIM is crucial for hair follicle formation and regeneration by controlling cilia formation and hedgehog signaling through its interaction with Cortactin and Src.
25 citations,
November 2014 in “Ageing Research Reviews” Skin aging is caused by stem cell damage and can potentially be delayed with treatments like antioxidants and stem cell therapy.
7 citations,
May 2020 in “Trends in molecular medicine” The document concludes that the immune-inhibitory environment of the hair follicle may prevent melanoma development.
1 citations,
October 2017 in “Journal of Investigative Dermatology” Blocking a specific enzyme can reduce the negative impact of stress hormones on hair growth cells.
October 2017 in “Journal of Investigative Dermatology” The Siah1 and Siah2 genes are active in mouse skin development and hair growth, especially right after birth.
October 2017 in “Journal of Investigative Dermatology” Certain miRNAs might be involved in a hair loss condition called frontal fibrosing alopecia and could possibly help in its diagnosis.
October 2017 in “Journal of Investigative Dermatology” Finasteride helps female-pattern hair loss.
506 citations,
March 2005 in “The Journal of Clinical Endocrinology and Metabolism” Testosterone therapy improves physical function, strength, and body composition in older men with low testosterone levels.
195 citations,
February 2007 in “The Journal of Clinical Endocrinology and Metabolism” Dutasteride and finasteride may reduce sperm count and volume but don't affect movement or shape; effects are reversible after stopping.
163 citations,
November 2003 in “Journal of Investigative Dermatology” Low iron levels may be linked to some types of hair loss in women.
142 citations,
February 1985 in “Fertility and sterility” Spironolactone reduced hair thickness and some testosterone levels in women with excessive hair growth.
117 citations,
September 2003 in “Molecular & cellular proteomics” The technology can help diagnose and subtype autoimmune diseases by identifying specific autoantibodies.
89 citations,
December 2006 in “Lancet Oncology” Taking 1 mg/day finasteride for hair loss significantly lowers PSA levels in men, which may affect prostate cancer screening.
83 citations,
November 2002 in “British Journal of Dermatology” Low iron levels are not directly linked to chronic hair loss and iron supplements may not help.
83 citations,
April 1992 in “Clinical Endocrinology” Having enough iron improves the effectiveness of a specific hair loss treatment in women.
78 citations,
August 2012 in “Human molecular genetics online/Human molecular genetics” A new gene, JMJD1C, may affect testosterone levels in men.
77 citations,
November 2007 in “International Journal of Andrology” Testosterone with or without finasteride doesn't improve thinking skills in older men with low testosterone.
73 citations,
January 2013 in “Annals of Dermatology” People with hair loss, especially those with certain types, have lower zinc levels, and zinc supplements might help.
72 citations,
April 2008 in “The Journal of urology/The journal of urology” Dutasteride and finasteride do not significantly affect bone density, blood fats, or blood production, but slightly lower PSA levels and minimally impact sexual function in healthy young men.
71 citations,
January 2016 in “International Journal of Trichology” Biotin deficiency is not a major cause of hair loss in women, so biotin supplements are not likely to be an effective hair loss treatment.
71 citations,
January 2014 in “Journal of Proteome Research” Women with PCOS have different levels of certain fats and proteins in their blood, which could help diagnose the condition.
65 citations,
January 2009 in “Annals of Dermatology” Zinc supplements increased zinc levels in some hair loss patients but didn't significantly improve hair growth.
65 citations,
October 1999 in “Journal of The American Academy of Dermatology” Finasteride effectively reduces hair loss by decreasing androgen levels.