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This study observed that the cream-mask and gel-mask with Serenoa repens and Sophora japonica applied to a rat model of androgenic alopecia stimulated hair follicle growth similarly to a reference minoxidil treatment.

In this study, application of Revgrey® hair serum was found to be safe and may offer some benefit in treating premature greying of hair, with slightly to moderately increased hair recovery observed in a small group of patients after 12 weeks.

This study established that a human epidermal model can be utilized to assess 5alpha-reductase activity and evaluate enzyme modulators, such as finasteride, for dermatological applications.

This article reviews the implications of post-SSRI sexual dysfunction syndrome and underscores the need for further epidemiological research to understand the condition and potential treatments, without offering new results.

This article discusses Serenoa repens for androgenetic alopecia and reports no strong evidence of its effectiveness, emphasizing the need for larger clinical trials.

This study found that suppressing allopregnanolone production in late gestation fetal sheep altered CNS activity and behavioral responses to transient asphyxia, effects mitigated by an analog co-infusion.

Some patients may experience lasting sexual dysfunction, depression, and other side effects from 5α-reductase inhibitor therapy.

This study developed a specific radioimmunoassay to measure minoxidil levels in human serum directly from a single oral dose.

This review discusses the impact of 5α-reductase inhibitors on sexual function and presents results from a meta-analysis of randomized controlled trials, without reporting new clinical findings.

In this study, oral etretinate resulted in increased hair length and loss of beading in a childhood monilethrix case, while the scalp's keratosis pilaris persisted.

This study found that combining Aliaxin® Global Performance with Viscoderm® Skinkò E improved hydration and appearance of nasolabial folds more effectively than using Aliaxin® Global Performance alone.

In this prospective, placebo-controlled study, the researchers observed a significant reduction in hair shedding in women after applying the combined topical treatment DA-OTC-002, containing synephrine and TAAR agonists, compared to placebo, showing a 62.5% average reduction with no reported adverse events.

This study found that the synthesized compound 7b exhibited higher 5α-reductase inhibitory activity, increased solubility, and dissolution compared to finasteride, suggesting its potential as a lead compound for benign prostatic hyperplasia treatment.

This article reviews the current status of oral retinoids in dermatology and reports no new clinical findings.

This study found that a synthetic avicequinone C analogue, 5e, was significantly more potent in inhibiting steroid 5α-reductase type 1 activity in human keratinocytes compared to the original isolated compound.

In a cell-free test setting, this study found that a novel saw palmetto extract effectively inhibited the 5α-reductase type II enzyme, showing promising bioactivity comparable to finasteride for promoting prostate health.

This review discusses the efficacy of the lipidosterolic extract of Serenoa repens for treating lower urinary tract symptoms and reports no new clinical results; the authors propose further examination of the existing literature and guidelines.

In this study, novel substituted benzoyl benzoic acids and phenylacetic acids were potent and selective inhibitors of human steroid 5alpha-reductase type 2, with one compound showing promising bioavailability in rats for potential clinical evaluation.

This study evaluates the compatibility of six active pharmaceutical ingredients, including finasteride and spironolactone, with TrichoFoam™, a foam vehicle used in personalized treatments for alopecia, though it does not report specific results.

In this study, topical phenylephrine significantly reduced hair shedding and increased the force needed to pluck hair in women undergoing cosmetic procedures, suggesting its potential utility for traction alopecia.

This study found that cyproterone acetate with ethynyl estradiol improved acne and seborrhea within 3–6 months in women, but had less satisfactory results for alopecia and hirsutism.

This study found that nonobese women with idiopathic hirsutism exhibited lower nitrite/nitrate concentrations and higher fibrinogen levels compared to control subjects, but these were similar to levels in women with polycystic ovary syndrome.

This study found that topical Rosmarinus officinalis leaf extract improved hair regrowth in mice and inhibited androgen-associated mechanisms involved in hair loss.

SPET-085 effectively inhibits an enzyme linked to prostate issues, similar to finasteride.

This article reviews the effects of 5 alpha-reductase inhibitors for treating conditions like male pattern baldness and benign prostatic hyperplasia, noting significant DHT reduction but reports no new clinical results.

Different treatments for skin conditions were found to be effective and generally safe, with biologics recommended as the first choice for generalized pustular psoriasis.

This systematic review analyzed treatments for androgenetic alopecia, finding that combining two therapies, such as oral minoxidil with another treatment, resulted in better outcomes than using monotherapies alone, though some patients experienced non-severe side effects.

This study confirmed that an injectable implant known as RISUG-PH™, when administered via the vas deferens, successfully delivers the drug Finasteride to the prostate in male rats for up to 28 days, suggesting a potential localized alternative to oral delivery methods.

In this study, a new apple stem cell extract serum significantly improved signs of skin aging and enhanced cell metabolism in human senescent fibroblasts, showing visible effects after one week of use.