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This study used TMT-based quantitative proteomics to analyze the development of secondary hair follicles in fetal sheep, revealing increased follicle density and key proteins involved, such as COL1A1 and THBS4, indicating their potential role in wool quality traits.

Some people have a genetic variation that makes them less effective at breaking down drugs.

This article outlines methods to study the skin and its molecular traits, focusing on interpretation and techniques applicable to mouse models, including diverse assays and approaches like electron microscopy and large-scale lipid analyses.

In this study, researchers developed a leech-inspired microneedle platform for targeted delivery of metformin to hair follicle cells, which showed promising results in reducing inflammation and oxidative stress and promoting hair growth, offering a potential new treatment strategy for androgenetic alopecia.

This study used single-cell and spatial transcriptomic profiling to identify specific molecular markers in human follicular dermal papilla cells, enhancing understanding of their role in hair follicle development.

This study observed that PCR-based genotyping for cre-loxP mice can lead to errors due to cre-mediated recombination in non-target tissues like tails, affecting the detection of lox alleles.

This review discusses advancements and gaps in using proteomics for hair testing and its potential in developing a medical proteome repository, but reports no new research findings.

In this study, a machine learning framework incorporating the CatBoost algorithm accurately predicted Systemic Lupus Erythematosus in Omani patients, suggesting potential for early clinical intervention.

This study reports that electrophoretic patterns of hair keratins are more similar among family members than unrelated individuals, potentially aiding genetic studies.

The microneedle arrays effectively promote wound healing and have potential for clinical use.

This study found that the TrichoScan method for evaluating hair loss showed excellent correlation with manual marking and provided more consistent, reproducible results with less variability and operator error.

This study presents a novel hydrogel scaffold made from tilapia collagen, which when activated by ultrasound, reprograms macrophages to promote wound healing, enhance angiogenesis, and stimulate hair follicle regeneration, offering a potential new method for treating inflammatory wounds.

This research concluded that the novel hydrogel PlacMA, derived from human placenta and curable by visible light, shows promise for cell culture and tissue engineering applications due to its tunable properties.

D-chiral biomaterial scaffolds enhance tissue and hair regeneration by activating the body's immune system.

This review discusses the complexity and genetic organization of human keratin gene clusters and addresses the ongoing need for an updated unified naming system; it reports no new clinical results.

This database provides detailed physiological parameters of porcine skin to enhance the MPML MechDermA Model, improving dermal absorption predictions for human studies in the Simcyp Simulator.

This study identified a specific hemizygous intronic variant in the MBTPS2 gene associated with IFAP syndrome in a patient, revealing exon skipping and reduced normal transcript expression through long-read RNA sequencing.

This study found that prevelex coatings on microwell array devices enhanced the formation of uniform cell spheroids and enabled the development of hair follicles in tissue engineering applications.

In this study, researchers used single-cell RNA sequencing to identify cell types and molecular differences in subcutaneous adipose tissue from various anatomical sites, suggesting that certain subpopulations of human adipose stem cells might improve the treatment of chronic refractory wounds.

This publication presents a library of geometric medicines designed to selectively target pathogenic bacteria and fungi with high precision while minimizing ecological harm, available for free on a non-commercial basis.

In this case study, a 26-year-old female with PLEC mutations and features of muscular dystrophy and myasthenia gravis showed significant improvement in symptoms following steroid treatment.

This paper discusses the recent advancements and challenges of flexible bioelectronics in personalized health management and cancer therapy, but reports no new studies or results.

This study reported that a magneto-responsive transdermal microneedle system delivered Minoxidil effectively and significantly increased hair density by 800% in mice with androgenetic alopecia after 10 days.

This case report describes a 19-year-old patient with systemic lupus and a composite heterozygosis SC with thalassemic component, highlighting the diagnostic challenge when symptoms of both conditions occur simultaneously.