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This review highlights the importance of selecting high-quality bioassays in discovering bioactive compounds from marine sources, emphasizing their role in evaluating safety and efficacy during pharmaceutical, food supplement, and cosmetic development.

This study on Sdr16c5/Sdr16c6-null mice found that inactivating these genes significantly increased Meibomian gland secretions and altered lipid profiles but had a subtle impact on sebogenesis, suggesting the genes control a bifurcation point in meibogenesis pathways.

This review discusses the potential of curcumin and its formulations to mitigate neuropathic and postoperative pain, highlighting positive outcomes in preclinical and clinical studies but noting the need for further clinical research.

In this study, prolonged systemic administration of 17β-estradiol in castrated male mice delayed wound healing by inhibiting re-epithelialization and reducing collagen accumulation, with estrogen receptor-α likely mediating this effect.

This review establishes a tolerable upper intake level of 255 μg/day for selenium in adults, warning that supplements and Brazil nuts may cause excess intake.

This study found that nanofibers combining a polydopamine coating and curcumin nanocrystals were effective in treating diabetic wounds infected with methicillin-resistant Staphylococcus aureus by providing sequential photothermal antibacterial action and promoting M2 macrophage polarization, which accelerated wound healing through enhanced angiogenesis and cell proliferation.

This study reports that chemotherapy-induced alopecia in mice may be linked to decreased laminin-511 and increased laminin-332 around hair follicles, suggesting a potential mechanism for abrupt hair loss.

This study reported that an ATRA-loaded nanostructured lipid carrier gel (ATRA-NLC-Gel) improved symptoms of alopecia areata in mice by enhancing transdermal drug delivery, reducing skin irritation, and promoting hair regrowth through targeted follicle enrichment and pathway activation.

In this study, BALB/c mice with burn injuries treated with SES-low or SES-low combined with a gel showed better wound healing and organization compared to placebo and common treatments like silver sulfadiazine, highlighting SES-low's effectiveness in promoting favorable healing outcomes.

In this animal study, researchers found that the simultaneous deletion of ERBB2 and ERBB3 in mice results in impaired skin differentiation, inflammation, and sebaceous gland alteration, leading to skin lesions, while highlighting potential side effects in cancer therapies targeting these receptors.

This study found that patients with alopecia areata and androgenetic alopecia showed increased c-kit expression and decreased Ki-67 expression in hair follicle cells compared to controls, suggesting a possible feedback mechanism involving stem cell factor signaling.

This study developed a new semiquantitative grading scale for frontal and vertex androgenetic alopecia, which was found to be more sensitive and objective than existing classifications.

This study found that intralesional vitamin D3 injections significantly improved hair regrowth in adults with patchy alopecia areata, as measured by a 5-point semiquantitative regrowth score and dermoscopic assessment, suggesting it may be an effective and affordable treatment.

This study found that hirsutism is more prevalent in Chinese women with PCOS compared to the general population, and the Ferriman-Gallwey score is a good predictor for diagnosing PCOS in this group.

This study found that TRH modulates specific keratins in human scalp tissue, suggesting its potential influence on hair growth and the need for further exploration of neuroendocrine controls in keratin expression.

This figure in the publication investigates the relationship between expression levels and tumor burden but reports no specific findings or conclusions.

This study found that digital droplet PCR (ddPCR) outperformed qPCR in detecting replication competent lentivirus in CAR-T products by offering better sensitivity, specificity, and reproducibility, making it a reliable and rapid method for ensuring patient safety.

This study concluded that allele-specific PCR (AS-PCR) is more reliable than tetra-primer ARMS-PCR for genotyping the SNP rs1998076 due to better stability and interpretability.

This paper details a method for measuring testosterone metabolism into seven androgens using digital autoradiography, which offers high sensitivity and reduces the need for radioactive materials.

In this study, the authors explore and compare advanced high-performance methods for transcriptome analysis, emphasizing the significant role of next-generation sequencing in understanding gene expression and revealing new RNA species.

This review highlights the potential of integrating point-of-care testing with allele-specific amplification techniques like AS-PCR, AS-LAMP, and AS-RPA to improve the efficiency, accuracy, and affordability of genotyping single nucleotide polymorphisms associated with human diseases.

This study demonstrated that combining cell conditioning with mild protease digestion enhanced the visualization of versican mRNA in formalin-fixed mouse skin tissue sections compared to using either technique alone.

This study developed a new STR typing strategy for forensic casework, enabling the simultaneous analysis of 11 polymorphic systems, particularly useful for limited or degraded DNA samples such as telogen hair roots.

This case report describes how real-time PCR rapidly identified Trichophyton mentagrophytes in a dog's dermatophytosis when traditional mycological methods were slower.

This study observed that PCR-based genotyping for cre-loxP mice can lead to errors due to cre-mediated recombination in non-target tissues like tails, affecting the detection of lox alleles.

This study details a step-by-step protocol for preparing mammalian skin samples, including hair follicles, for spatial transcriptomics to overcome challenges inherent in applying this technique to the skin.

In this study, the researchers developed a quantum algorithm, QuantAnts machines, which identified complexes of CD9, CD34, and CD74 as potential targets for certain cancers involving the RAS pathway.