research Neurosteroids on the Epilepsy Chessboard: Keeping Seizures in Check
Ketogenic diet, neurosteroids, and HMGB1-TLR4 signaling pathway are potential targets for new epilepsy treatments.
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research Registrars’ Symposium: Summaries of Papers
Lower adrenal hormone levels may cause hair loss in postmenopausal women, certain patterns help diagnose nail cancer, and a gene variant linked to higher skin cancer risk in kidney transplant patients suggests monitoring folate levels.
research In Vivo Transcriptional Governance of Hair Follicle Stem Cells by Canonical Wnt Regulators
Wnt signaling controls whether hair follicle stem cells stay inactive or regenerate hair.
research What's New in Dermatological Research?
2011 dermatological research found new skin aging markers, hair loss causes, skin defense mechanisms, and potential for new treatments.
research Viewpoint 3
Oxidative stress plays a significant role in vitiligo, and both skin and non-skin cells may be involved.
research Editorial: Machine Learning Techniques on Gene Function Prediction Volume II
Machine learning is effective in predicting gene functions and their relationships with diseases.
research Novel Mutations of the ABCA12, KRT1 and ST14 Genes in Three Unrelated Newborns Showing Congenital Ichthyosis
New genetic mutations linked to rare skin disorders were found in three newborns.
research Fetal Alpha 5-Reductase Val89Leu Mutation Is Associated With Late Miscarriage
A certain mutation in the fetal alpha 5-reductase gene is linked to a higher risk of late miscarriage.
research Differential Expression Levels of Sox9 in Early Neocortical Radial Glial Cells Regulate the Decision Between Stem Cell Maintenance and Differentiation
Sox9 levels in brain stem cells affect whether they stay as stem cells or become neurons.
research Design and Synthesis of Novel Azasteroids and Pseudoazulenyl Nitrones
The research created new azasteroids and pseudoazulenyl nitrones, which could be useful in medicine.
research High Performance Conditioning Shampoo with Hyaluronic Acid and Sustainable Surfactants
The best shampoo formula used 1% high-weight hyaluronic acid, 10% acidic sophorolipid, and 1% salt for effective hair conditioning and cleansing without sulfates or silicones.
research Self-Assembled Complete Hair Follicle Organoids by Coculture of Neonatal Mouse Epidermal Cells and Dermal Cells in Matrigel
Scientists created complete hair-like structures by growing mouse skin cells together in a special gel.
research Dermatological Drugs, Topical Agents, and Cosmetics
Dermatological drugs and cosmetics can cause serious side effects like cancer, allergies, and heart issues.
research Hair Loss Associated with Sertraline: Two Case Reports and Review
Sertraline, an antidepressant, may rarely cause hair loss.
research Summary of the Preceding Three Alopecia Areata Research Summits: What’s Past Is Prologue
New treatments and strategies are needed for Alopecia Areata, focusing on immune response and better trial designs.
research A Guide to the Use of Bioassays in Exploration of Natural Resources
Bioassays help find useful compounds in nature for making medicines, supplements, and cosmetics.
research Blue-Gray Discoloration of the Skin After Levofloxacin Exposure in a 44-Year-Old Man With Pulmonary Tuberculosis
Levofloxacin may cause skin discoloration and hair loss as side effects.
research Effect of Minoxidil on Trabecular Outflow via the Paracellular Pathway
Minoxidil increases cell layer permeability by reducing tight junction proteins and raising ROS levels.
research Hair Loss Associated with Sertraline: Two Case Reports and Review
Sertraline, an antidepressant, may cause hair loss in rare cases.
research Radiation-Induced Microvascular Injury as a Mechanism of Salivary Gland Hypofunction and Potential Target for Radioprotectors
Radiation damages salivary glands by harming blood vessels, but antioxidants might help protect them.
research Elevated Ornithine Decarboxylase Activity Promotes Skin Tumorigenesis by Stimulating the Recruitment of Bulge Stem Cells but Not via Toxic Polyamine Catabolic Metabolites
Increased ODC activity leads to skin tumors by recruiting stem cells, not by toxic byproducts.
research Novel Insights Into the Molecular Mechanisms Underlying Generalized Glucocorticoid Resistance and Hypersensitivity Syndromes
Genetic defects in the glucocorticoid receptor gene can cause conditions with abnormal sensitivity to stress hormones, and other factors may also affect this sensitivity.
research Nitric Oxide: Physiological Functions, Delivery, and Biomedical Applications
Nitric Oxide has potential in medicine, especially for infections and heart treatments, but its short life and delivery challenges limit its use.
research How Biotin Induces Misleading Results in Thyroid Bioassays: Case Series
Taking biotin supplements can cause incorrect thyroid test results, leading to wrong diagnoses.
research Two Mutations at KRT74 and EDAR Synergistically Drive the Fine-Wool Production in Chinese Sheep
Two mutations in KRT74 and EDAR genes cause sheep to have finer wool.
research Blue Laser Irradiation Decreases ATP Levels in Mouse Skin and Increases Production of Superoxide Anion and Hypochlorous Acid in Mouse Fibroblasts
Blue laser light reduces energy in mouse skin cells and creates harmful oxygen compounds, possibly harming the cells.
research Production and Characterization of Human Hair Keratin Bioplastic Films With Novel Plasticizers
Human hair was used to make biodegradable plastic films that could be useful for packaging and disposable products.
research Baricitinib Demonstrates Rapid Action Within Just 2 Months of Treatment in Severe and Unresponsive Alopecia Areata: A Case Report
Baricitinib quickly improved severe alopecia areata, with almost total hair regrowth in three months.
research Rational Design of Keratin Nanoparticles Utilizing Diverse Hair Protein Fractions for Controlled Drug Release
Scientists made nanoparticles from human hair proteins to improve drug delivery.
research Patient Prioritisation of Impact Items to Develop the Patient-Reported Impact of Dermatological Diseases (PRIDD) Measure: European Delphi Data
Patients with skin diseases rated psychological effects as most impactful, needing a treatment approach that addresses both mind and body.