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    Glossary Scars

    areas of fibrous tissue replacing normal skin post-injury

    Scars are areas of fibrous tissue that replace normal skin after an injury. They form as part of the body's natural healing process when the dermis (the deep, thick layer of skin) is damaged. While the new tissue is made of the same protein (collagen) as the tissue it replaces, its fiber composition is different, often resulting in a different texture and appearance.

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    Research 30 of 1000+

    1. Postmenopausal frontal fibrosing alopecia. Scarring alopecia in a pattern distribution Archives of Dermatology · 1994 · 332 citations
    2. Recent Understandings of Biology, Prophylaxis and Treatment Strategies for Hypertrophic Scars and Keloids International journal of molecular sciences · 2018 · 305 citations
    3. Asebia-2J (Scd1ab2J): A New Allele and a Model for Scarring Alopecia ˜The œAmerican journal of pathology · 2000 · 179 citations
    4. Cutaneous Scarring: Basic Science, Current Treatments, and Future Directions Advances in wound care · 2016 · 178 citations
    5. Regeneration of Dermis: Scarring and Cells Involved Cells · 2019 · 176 citations
    6. Differential Expression of Fibromodulin, a Transforming Growth Factor-β Modulator, in Fetal Skin Development and Scarless Repair American Journal of Pathology · 2000 · 168 citations
    7. Scarless wound healing: finding the right cells and signals Cell and Tissue Research · 2016 · 132 citations
    8. Scars or Regeneration?—Dermal Fibroblasts as Drivers of Diverse Skin Wound Responses International Journal of Molecular Sciences · 2020 · 123 citations
    9. Toward understanding scarless skin wound healing and pathological scarring F1000Research · 2019 · 113 citations
    10. New insights into balancing wound healing and scarless skin repair Journal of Tissue Engineering · 2023 · 108 citations
    11. Human Wharton’s Jelly Mesenchymal Stem Cells Plasticity Augments Scar-Free Skin Wound Healing with Hair Growth PloS one · 2014 · 102 citations
    12. Confocal Microscopic Analysis of Scarless Repair in the Fetal Rat Plastic & Reconstructive Surgery · 2002 · 99 citations
    13. Microskin‐Inspired Injectable MSC‐Laden Hydrogels for Scarless Wound Healing with Hair Follicles Advanced Healthcare Materials · 2020 · 89 citations
    14. Elastic tissue in scars and alopecia Journal of cutaneous pathology · 2000 · 80 citations
    15. Scarless wound healing: Transitioning from fetal research to regenerative healing Wiley Interdisciplinary Reviews-Developmental Biology · 2018 · 79 citations
    16. Scarring, stem cells, scaffolds and skin repair Journal of Tissue Engineering and Regenerative Medicine · 2013 · 69 citations
    17. An In Vivo Mouse Excisional Wound Model of Scarless Healing Plastic and Reconstructive Surgery · 2006 · 58 citations
    18. Hair Follicle Biology, the Sebaceous Gland, and Scarring Alopecias Archives of dermatology · 1999 · 57 citations
    19. Primary Follicular Dystrophy With Scarring Dermatitis in C57BL/6 Mouse Substrains Resembles Central Centrifugal Cicatricial Alopecia in Humans Veterinary pathology · 2010 · 56 citations
    20. Engineering Pro‐Regenerative Hydrogels for Scarless Wound Healing Advanced Healthcare Materials · 2018 · 55 citations
    21. Stem cell markers (cytokeratin 15, CD34 and nestin) in primary scarring and nonscarring alopecia British Journal of Dermatology · 2009 · 54 citations
    22. Skin wounds in the MRL/MPJ mouse heal with scar Wound Repair and Regeneration · 2006 · 51 citations
    23. The Spectrum of Scarring in Craniofacial Wound Repair Frontiers in Physiology · 2019 · 48 citations
    24. Cicatricial (Scarring) Alopecias American Journal of Clinical Dermatology · 2012 · 44 citations
    25. Pro‐Regenerative Hydrogel Restores Scarless Skin during Cutaneous Wound Healing Advanced Healthcare Materials · 2017 · 41 citations
    26. Hydrogen peroxide disrupts scarless fetal wound repair Wound Repair and Regeneration · 2005 · 41 citations
    27. The stretched scar: the benefit of prolonged dermal support British Journal of Plastic Surgery · 1989 · 37 citations
    28. Biomaterial-based mechanical regulation facilitates scarless wound healing with functional skin appendage regeneration Military Medical Research · 2024 · 37 citations
    29. Novel Biodegradable Polymeric Microparticles Facilitate Scarless Wound Healing by Promoting Re-epithelialization and Inhibiting Fibrosis Frontiers in Immunology · 2018 · 37 citations
    30. Sebaceous gland loss and inflammation in scarring alopecia: A potential role in pathogenesis Journal of The American Academy of Dermatology · 2011 · 37 citations