January 2025 in “International Journal of Veterinary Sciences and Animal Husbandry” In this case study, researchers found that treatment with sarolaner led to complete recovery from generalized demodicosis in six dogs within four weeks, resolving clinical signs without adverse reactions.
7 citations
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January 1989 in “Archives of Dermatological Research” The side gland of Suncus murinus is a good model for studying human sebaceous glands.
This study identified several compounds, including Pictilisib and Nimorazole, that may have higher binding affinity for SARS-CoV-2 main protease than existing inhibitors, potentially offering new treatment alternatives for Covid-19.
January 1975 in “NJEA Review” This Phase II study found that BAY 43-9006, given at 400 mg orally twice daily, led to stable disease in 30% and tumor reduction in 40% of renal cell carcinoma patients.
March 2024 in “Jurnal Ilmu Kesehatan Hewan” In this case report, treatment involving anthelmintic pyrantel pamoate and antiparasitic sarolaner effectively reduced pruritus and physical symptoms of scabiosis and ancylostomyosis in a puppy, with notable improvements observed by day 14.
3 citations
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January 2018 in “Postępy Dermatologii i Alergologii” This study suggests that SRD5A2 polymorphisms may increase the risk of acne in individuals with normal serum testosterone levels, particularly in the Chinese population.
June 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This source describes SH‑1 as a next-generation androgen receptor antagonist designed for localized treatment of androgenetic alopecia, aiming to reverse follicular miniaturization while maintaining endocrine balance. Unlike traditional therapies, SH‑1 offers tissue-specific action, avoiding systemic effects.
47 citations
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November 2012 in “Expert Opinion on Therapeutic Patents” The document concludes that research on sulfatase inhibitors should continue due to their potential in treating various diseases, despite some clinical trial failures.
20 citations
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February 2004 in “Clinical & Experimental Immunology” This study suggests that long-term treatment with the contact sensitizer SADBE in mice may reduce leucocyte traffic in alopecia areata through impaired leucocyte extravasation.
21 citations
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December 2014 in “Clinics in dermatology” This review discusses squaric acid dibutylester's use, effects, and safety in treating alopecia areata, but reports no new clinical results.
1 citations
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February 2023 in “Tropical Journal of Pharmaceutical Research” This study found that polysulfonic acid mucopolysaccharide may reduce skin scarring in rats by influencing the TGF-β1/Smad signaling pathway.
8 citations
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December 2021 in “BMJ neurology open” This study on Alzheimer's patients found that chronic sodium selenate treatment (up to 23 months) was safe and well-tolerated, with most adverse events being mild, and suggested potential slowing of cognitive decline, though confirmation requires further controlled studies.
October 2018 in “Elsevier eBooks” This source reports that Serenoa repens may be an effective and safe natural remedy for treating benign prostatic hyperplasia, possibly working through mechanisms like apoptosis stimulation, 5-alpha-reductase inhibition, and blocking DHT receptor interactions, with minimal side effects.
15 citations
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December 2014 in “Dermatology and therapy” This study reports that sorafenib-associated facial acneiform eruption, mimicking chloracne, is a rare cutaneous adverse event which improved upon reducing or discontinuing the drug.
25 citations
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February 2013 in “The journal of investigative dermatology/Journal of investigative dermatology” In this study, topical application of the SCD1 inhibitor XEN103 significantly reduced sebaceous gland size and number in mouse skin, suggesting potential local therapeutic effects for acne treatment without systemic side effects.
July 2023 in “Pharmacognosy Magazine” This study found that Cerasus serrulata extracts, when obtained through specific methods, demonstrate significant antioxidative and antibacterial properties, as well as potential anti-alopecia effects in a mouse model, potentially making them useful supplements for these purposes.
17 citations
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April 2015 in “Tropical Journal of Pharmaceutical Research” This review highlights the traditional use and potential therapeutic activities of Asiasari Radix in drug discovery, but it reports no new clinical results.
August 2023 in “Journal of inflammation research” This case report observed alopecia universalis, a complete hair loss condition, in a patient during a clinical trial with the angiotensin receptor-neprilysin inhibitor sacubitril/alisartan, indicating that ARNI therapy might be associated with such cutaneous reactions.
1 citations
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April 2015 in “InTech eBooks” RAGE is a potential target for melanoma treatment, but its effectiveness is uncertain due to variable expression levels.
6 citations
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September 2024 in “Current Oncology” This review summarizes evidence and adverse event management recommendations for Sacituzumab Govitecan in metastatic triple-negative breast cancer and hormone receptor-positive breast cancer, emphasizing favorable survival data from clinical trials.
February 2026 in “Journal of Cosmetic Dermatology” This study found that a proprietary saw palmetto extract significantly improved hair growth in men and women with self-perceived thinning hair over a 6-month period, outperforming placebo on key hair growth parameters without any treatment-related adverse events.
2 citations
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March 2012 in “Current opinion in urology” This study suggests that 5-alpha-reductase inhibitors may reduce the rate of clinical progression in men with low-risk prostate cancer who choose active surveillance.
March 2026 in “Tropical Journal of Natural Product Research” In this study, the bark extract of Albizia saponaria was analyzed for its metabolites and potential anti-alopecia effects, identifying several compounds with predicted affinities for proteins involved in hair loss pathways.
6 citations
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November 2022 in “Antioxidants” In this study, sandalore was found to activate OR2AT4, which inhibits senescent cell traits and restores proliferation in human keratinocytes, suggesting potential anti-aging applications.
8 citations
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August 2014 in “Journal of Clinical Oncology” This article explores the historical development and evolution of stereotactic radiosurgery (SRS) and stereotactic body radiation therapy (SBRT), emphasizing advancements in safety and technology, and reports no new clinical results.
This study investigates whether adding 30% supramolecular salicylic acid to conventional treatment for mild to moderate acne vulgaris is safe and effective, though specific results are not reported in the abstract.
October 2014 in “Cancer research” This study found that targeting mTORC1 with rapamycin effectively inhibited skin tumor promotion in a mouse model, highlighting a potential target for cancer chemoprevention.
29 citations
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November 2021 in “FEBS Open Bio” In this study, molecular docking simulations and cell-based assays suggested that certain analogues of cepharanthine might possess anti-SARS-CoV-2 activity.
2 citations
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June 2022 in “International Journal of Molecular Sciences” This study found variable outcomes in hair loss treatment with autologous cell-based therapy using DSC cells, with certain gene markers showing inconsistent correlations with treatment efficacy.
4 citations
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January 1987 in “Beiträge zur Onkologie/Contributions to oncology” This study reported a 21% partial remission rate in patients with advanced soft tissue sarcomas treated with ifosfamide combination chemotherapy, with no complete remissions observed.