14 citations
,
June 2016 in “Hypertension research” The authors concluded that utilizing clock gene expression from hair follicle cells may improve circadian-phase estimation in clinical settings, aiding the detection of circadian-related sleep problems despite social time constraints.
1 citations
,
February 2022 in “Experimental Dermatology” This study found that the secretory profiles of adipose-derived stem cells vary between balding and non-balding scalp areas in androgenetic alopecia patients, suggesting involvement of angiogenic and inflammatory processes in the condition's development.
22 citations
,
January 2018 in “Experimental Dermatology” This article reviews insights into the pathogenesis of primary cicatricial alopecias, such as lichen planopilaris, provided by emerging technologies, but it does not report new clinical results.
June 2024 in “Computational and Structural Biotechnology Journal” This review discusses the integration of omics analyses in androgenetic alopecia research, reporting no new clinical results but suggesting that collaborative multi-omics studies may enhance understanding of AGA's pathomechanisms.
8 citations
,
July 2013 in “PLoS ONE” This study found that a new method using enzymatic laundry powder effectively extracts DNA from hair shafts, showing promise for genome-wide DNA analyses.
78 citations
,
August 2002 in “Experimental Dermatology” This study describes a simplified method for isolating and cultivating human hair follicle papillae that can be easily executed by new lab personnel.
14 citations
,
May 2008 in “Journal of proteome research” This study found that dutasteride reduced β-amyloid plaque load in a cerebral amyloidosis model, seemingly linked to mitochondrial apoptosis and autophagy processes.
17 citations
,
April 2007 in “Kidney international” This study found that 1,25 dihydroxyvitamin D3 significantly increased the expression and activity of vasculoprotective natriuretic peptide receptor-A in cultured inner medullary collecting duct cells, suggesting a potential mechanistic role in cardiovascular and renal benefits.
120 citations
,
June 2008 in “American Journal of Epidemiology” This study reported a 6.3% prevalence of PCOS among women in a Sri Lankan community, with most cases presenting as oligo/amenorrhea and polycystic ovaries.
12 citations
,
July 2017 in “Scientific reports” In this study, researchers developed a simple, non-invasive method to monitor circadian gene expression using whole hair root cultures, finding that elderly dementia patients' peripheral clocks still oscillate similarly to younger, healthier individuals, which suggests cellular senescence minimally affects some aspects of circadian rhythms.
October 2025 in “Progress In Microbes & Molecular Biology” This review reveals that PCOS is consistently linked to gut microbiota dysbiosis, characterized by reduced microbial diversity and shifts in composition, which are associated with various PCOS phenotypes and may present opportunities for microbiota-targeted therapies addressing the disorder's underlying pathophysiological mechanisms.
8 citations
,
July 2018 in “Analytical sciences” This study reported that derivatization with 5-butylpicolinic acid improved the sensitivity for detecting testosterone and DHT in saliva using LC-ESI-MS/MS, with minimal interference from the saliva matrix.
2 citations
,
November 2025 in “Journal of Ovarian Research” This study found that in a mouse model of PCOS, high androgen levels caused pyroptosis in ovarian granulosa cells and increased ER stress in oocytes, reducing oocyte maturation rates, while treatment with CPA and DMF improved these rates.
30 citations
,
October 2016 in “Current research in translational medicine” This essay reviews the role of human scalp hair follicles in the "brain-skin connection," highlighting their dual function as targets and sources of neurohormones, without reporting new experimental results.
12 citations
,
December 2017 in “Scientific reports” This study reported that pulverizing hair samples significantly improves the precision of testosterone measurement, with higher testosterone concentrations observed in men than in women.
6 citations
,
March 2018 in “Journal of Chromatography A” This study describes an analytical technique combining field-enhanced sample stacking with dispersive liquid-liquid microextraction, offering improved sensitivity for detecting finasteride and its metabolite in urine samples from patients treated for androgenetic alopecia.
November 2025 in “Biological Trace Element Research” This pilot study found no significant relationship between blood and hair mineral concentrations in generally healthy adults, though hair analysis may have potential for assessing long-term mineral trends.
August 2025 in “Japan Journal of Clinical & Medical Research” This study found a widespread vitamin D deficiency among medical laboratory visitors in Misurata City, with 80.42% of females and 19.57% of males affected, and higher deficiency rates during winter and spring, particularly in individuals aged 35–45.
24 citations
,
January 2011 in “International Journal of Trichology” This review highlights the light microscopic features of various infectious and non-infectious hair conditions and reports no new clinical results.
February 2024 in “BioMetals” This review found substantial data suggesting that heavy metals may influence tumor development and progression in cancers such as breast, lung, prostate, and gastric, though noted limitations and gaps in research data require further investigation.
39 citations
,
November 2017 in “Journal of The American Academy of Dermatology” This review presents standardized methods for assessing and tracking hair loss in alopecia areata but reports no clinical results, with the authors noting time limitations in clinical practice.
49 citations
,
December 2009 in “Journal of Investigative Dermatology” This review explores the complex relationship between thyroid hormones and skin, discussing potential mechanisms and known interactions but reports no new clinical results, emphasizing the need for further research.
10 citations
,
November 2024 in “Nature Reviews Cardiology” Skin conditions can signal heart issues, highlighting the need for integrated care.
5 citations
,
November 2020 in “Frontiers in Cell and Developmental Biology” This study introduced a simple and reliable in vitro assay capable of large-scale simultaneous screening of hair growth-promoting compounds using a 3D co-culture system of human dermal papilla and outer root sheath cells.
4 citations
,
May 2020 in “PLOS ONE” This study found that ingenol mebutate treatment led to gene expression changes in actinic keratoses, with complete lesion clearance in 40% of patients and identified genetic markers potentially predicting treatment response.
42 citations
,
January 2014 in “Cold Spring Harbor Perspectives in Medicine” This abstract omits specific findings and does not provide new research results.
4 citations
,
June 2019 in “International Journal of Dermatology and Venereology” This review discusses the link between metabolic syndrome and various inflammatory skin diseases and reports no new clinical results, emphasizing the importance of recognizing skin manifestations as early indicators of systemic metabolic disorders.
1 citations
,
October 2023 in “Frontiers in endocrinology” This study found that sex hormone-binding globulin promotes facial aging, while sex steroid hormones such as testosterone and estradiol inhibit it, with growth hormone levels showing no significant effect.
September 2024 in “arXiv (Cornell University)” This study evaluated various NLP models for detecting bias in medical curricula, finding that fine-tuned BERT models perform well, whereas LLMs, despite being state-of-the-art in many tasks, are unsuitable for this application.
January 2021 in “Scandinavian journal of clinical and laboratory investigation” This study presents a method using liquid chromatography tandem mass spectrometry to quantify biotin in plasma and serum, and explores how high biotin intake can interfere with diagnostic immunoassays that utilize biotin-streptavidin technology, potentially leading to misdiagnosis of endocrine disorders.