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240-270 / 1000+ resultsresearch Long-term Treatment with a 5-Alpha-Reductase Inhibitor AlleviatesDepression-like Behavior in Obese Male Rats
In this study, male Wistar rats with obesity showed reduced depressive-like behaviors, brain inflammation, and oxidative stress after long-term finasteride treatment, suggesting potential benefits of finasteride in obese conditions, while lean rats experienced adverse effects including metabolic disturbances and depressive-like behaviors.
research Surgical treatment of vitiligo
This study reported that surgical treatments for vitiligo, including tissue and cellular grafting methods, are safe and effective in selected patients, although specific advantages and disadvantages vary by technique.
research Comparison of Efficacy of Autologous Platelet Rich Plasma Therapy With 5% Topical Minoxidil Spray in Treating Alopecia Areata: A Head-to-Head Assessment of Novel Approaches
This study concluded that monthly intralesional autologous platelet-rich plasma therapy significantly decreased alopecia areata severity over four months compared to daily 5% topical minoxidil therapy.
research Efficacy and Tolerability of a Hyaluronic Acid-Based Extracellular Matrix for Labia Majora Rejuvenation and Augmentation: A Pilot Study
In this study, researchers found that an injectable solution of low-molecular-weight hyaluronic acid and amino acids significantly improved skin rejuvenation and elasticity in the labia majora of post-menopausal women over 12 weeks, with a reported 25% or greater aesthetic improvement and high patient satisfaction.
research Syphilis and Beyond: A Comprehensive Analysis of Associated Infections and Comorbidities in a Five-Year Retrospective Study in the United Arab Emirates (2018-2022)
This study observed a marked increase in syphilis frequency within the studied population in 2020, along with dynamic patterns of clinical manifestations and increasing re-infection rates.
research Retraction Note: The gastro protective effects of Cibotium barometz hair on ethanol-induced gastric ulcer in sprague-dawley rats
The article on the stomach-protecting effects of Cibotium barometz hair was retracted due to unreliable data.
research Comparison of Efficacy of Topical Betamethasone Dipropionate and Topical Minoxidil in Patients With Alopecia Areata
In this nonrandomized controlled study, topical betamethasone dipropionate lotion was found to be significantly more effective for hair regrowth in patients with alopecia areata compared to topical minoxidil solution, with 74% showing efficacy versus 42%, respectively.
research Dietary Habits and their Impact on Physical Symptoms Severity in Young Females Diagnosed with PCOS
In this study of women diagnosed with PCOS, a correlation was found between the severity of physical symptoms and poor dietary habits, suggesting diet plays a role in managing the condition.
research Characteristics of hair loss in COVID-19 patients in Thailand.
This study reviewed hair loss characteristics in Thai patients post-COVID-19 infection, finding that telogen effluvium commonly occurred 30 days after infection onset, with female gender linked to more severe hair shedding while preexisting androgenetic alopecia was linked to less severe shedding.
research Chronic Exposure with 5‐Alpha Reductase Inhibitor Ameliorates Anxiety and Depression‐like Behaviors By Reducing Systemic Oxidative Stress in D‐galactose‐Induced Aging Male Rats
In this rodent study, researchers found that the drug finasteride may reduce anxiety and depression-like behaviors in a model of aging, despite inducing metabolic disturbances and depressive-like behaviors in young rats, suggesting potential considerations for its use in elderly populations.
research Chronic Exposure of 5‐Alpha Reductase Inhibitor in Young Male Rats Induces Not Only Metabolic Disturbance, But Also Depressive‐Like Behaviors as Similar with Obese Condition
In this study, chronic exposure to finasteride induced metabolic disturbances and depression-like behaviors in young male rats, similar to those caused by obesity, but did not worsen anxiety or depression in obese rats.
research Finasteride effectively attenuates the impairments of left ventricular function and cardiac sympathovagal balance in both aging and obese male rats via reducing systemic oxidative stress
In this study, finasteride improved cardiac sympathovagal balance in aging and obese male rats, also enhancing left ventricular function specifically in those modeled for aging, but not affecting healthy rats.
research Age-Related Macular Degeneration in Patients with Androgenetic Alopecia: Could the Monocyte/HDL Ratio Be the Link?
In this study, AMD was observed more frequently in AGA patients, and a higher monocyte/HDL ratio was associated with increased AMD severity, especially in men.
research A case report of occurrence of severe alopecia areata as post-COVID-19 complication
In this case report, a 33-year-old woman with severe post-COVID alopecia areata experienced hair regrowth after two months of treatment with topical minoxidil, tacrolimus, and scalp PRP with micro-needling, though some bald patches reoccurred.
research A 15-YEAR-OLD FEMALE PATIENT DIAGNOSED WITH SYSTEMIC LUPUS ERYTHEMATOSUS (SLE) AND INITIALLY PRESENTED WITH LUPUS NEPHRITIS, CEREBRITIS, AND DIFFUSE ALVEOLAR HEMORRHAGE (DAH)
This case report illustrates that diffuse alveolar hemorrhage can be a serious initial manifestation of systemic lupus erythematosus, characterized by progressive dyspnea, hemoglobin decrease, and respiratory symptoms.
research FREQUENCY OF SKIN MANIFESTATIONS IN PATIENTS ON CHEMOTHERAPY
This study found that patients undergoing chemotherapy frequently experienced skin manifestations, with alopecia, mucositis, and dry skin being the most common, irrespective of age or gender.
research Polycystic Ovary Syndrome (PCOS): A Concerning Hormonal Condition and its Bodily Impact on Women
This review discusses the complex pathophysiology, diagnosis, and management of Polycystic Ovary Syndrome and reports no new results, underscoring the need for comprehensive treatment plans.
research Efficacy of oral isotretinoin in the treatment of acne vulgaris
This study found that oral isotretinoin was effective and safe for treating acne vulgaris in a dermatology clinic in Aden, with 80.2% of patients achieving complete clearance and significant differences in acne severity based on age groups.
research Lipedematous alopecia, an entity on the rise
This case report describes a 59-year-old Afro-American woman diagnosed with lipedematous alopecia, a rare scalp condition of unknown cause.
research New frontiers in CRISPR/Cas9 delivery systems delivery for gene editing
This review discusses various methods for delivering CRISPR/Cas9 for gene editing in vitro and in vivo, highlighting delivery as a major challenge but reports no new experimental results.
research The first study on combined carboxytherapy and minoxidil 20% in the treatment of Lichen planopilaris: A case series and literature review
Combined carboxytherapy and minoxidil 20% may help treat Lichen planopilaris.
research A Functional Role of S100A4/Non-Muscle Myosin IIA Axis for Pro-Tumorigenic Vascular Functions in Glioblastoma
In this study, high expression of S100A4 in glioblastoma was associated with worse patient survival and promoted tumor progression by enhancing pro-tumorigenic vascular functions.
research Novel Formula as Mosquito Larvicide
This study found that combining prodigiosin and essential oil from Thuja orientalis leaves showed a synergistic effect against the 3rd larva stage of Cx. pipiens, significantly reducing acetylcholine esterase activity and altering midgut pH, compared to untreated larvae.
research 136 Physiological function of Krox20 (Egr2) in epithelial stem cells
Krox20 is crucial for hair growth and maintaining skin stem cells.
research Telogen effluvium: Long term Covid-19 symptom
This article presents cases of two patients experiencing excessive hair shedding 2 to 3 months after COVID-19 infection, highlighting a possible link to telogen effluvium.
research Eclipta alba (Family: Asteraceae): A review of botanical, ethnopharmacological, phytochemical and pharmacological studies
This review discusses a traditional medicinal plant used in various holistic health systems and reports its potential antitumor activity, but no new clinical results are provided.
research Issue Information
research Enzyme Inhibitory Activities of Marine Sponges Against Cholinesterase and 5α-Reductase
This study reported that methanolic extracts from marine sponges, particularly Petrosia sp. and Agelas nakamurai, showed significant enzyme inhibitory activities, with Petrosia sp. exhibiting notable 5?-reductase inhibition.
research To Evaluate Frequency Of Hirsutism In Afghan Women
The study observed that among Afghan women attending a gynecology outpatient department, the majority of those with hirsutism exhibited associated gynecological issues and were primarily categorized as having idiopathic causes or Polycystic Ovarian Disease.