129 citations
,
January 2004 in “Journal of medicinal chemistry” This study synthesized nonsteroidal ligands as second-generation androgen receptor agonists and identified three compounds with significant anabolic activity and moderate to minimal androgenic activity in vivo.
19 citations
,
June 2006 in “Physiology & Behavior” Finasteride slows down motherly behavior in first-time pregnant rats.
18 citations
,
January 2002 in “Chemical & pharmaceutical bulletin/Chemical and pharmaceutical bulletin” This study found that several new pregnane derivatives, especially steroids 16 and 19, demonstrated higher antiandrogenic activity on male hamster models than the commonly used finasteride.
6 citations
,
May 2013 in “PloS one” This study found that the Foxn1(-/-) nude phenotype significantly influences epithelial progeny in skin, with notable changes in stem cell niches not achievable in other models.
3 citations
,
September 2020 This study found that the medication dyclonine has a potent inhibitory effect on the TRPV3 channel, effectively rescuing cell death and alleviating pruritus symptoms in a mouse model with gain-of-function TRPV3 mutations, suggesting potential for treating skin inflammation.
3 citations
,
March 2020 in “International Journal of Molecular Sciences” This study found that overexpressing the gene Thymosin β4 (Tβ4) can promote the growth and development of secondary hair follicle dermal papilla cells in cashmere goats, suggesting its potential as a target for increasing cashmere production.
September 2025 in “Dermatology and Therapy” This systematic review and meta-analysis found that platelet-rich plasma (PRP) therapy is effective in increasing hair density and reducing hair loss for alopecia, with variations in response based on activation status.
October 2021 in “Research Society and Development” This review discusses potential drug interactions between herbal medicines and oral contraceptives, reporting no new research results but highlighting the risk these interactions pose to contraceptive effectiveness.
January 2019 in “Industrial Law Journal” This article reviews two new legislative measures affecting domiciliary care workers in Wales and reports no new research results; it highlights implications for labor law and devolution debates.
January 2003 in “Zhonghua shaoshang zazhi” In this study, murine fetal epidermal stem cells successfully formed new hair follicle structures when cografted with folliculus pili cells in nude mice.
51 citations
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June 1970 in “British journal of dermatology/British journal of dermatology, Supplement” This review discusses the biology of antiandrogens and highlights available bioassay models to predict their therapeutic effects on human skin, reporting no new clinical results.
48 citations
,
May 2012 in “Journal of Midwifery & Women's Health” This review discusses the symptoms, diagnosis, and current treatment recommendations for polycystic ovary syndrome, noting that many women may remain undiagnosed and at risk for complications.
11 citations
,
January 2013 in “International Journal of Trichology” This case report highlights a rare allergic reaction to 2-hydroxy ethyl meta acrylate, found in superglue, in a man who developed skin lesions from wearing a wig.
5 citations
,
May 2025 in “Scientific Reports” This study found that extracts from Indian gooseberry leaves showed strong antimalarial activity against Plasmodium falciparum, with low cytotoxicity, suggesting potential for developing new antimalarial drugs.
June 2018 in “The Journal of Sexual Medicine” In this study, finasteride was found to significantly reduce DHT levels and affect spermatogenic markers in rats, while DA-9401 co-treatment indicated potential ameliorative effects.
17 citations
,
May 2020 in “Forensic Science International Genetics” This study found that genetically variant peptides from human hair can reliably identify individuals despite differences in age and storage conditions, provided environmental and processing factors are controlled.
5 citations
,
January 2021 in “IEEE Access” In this study, researchers demonstrated that treating platelet rich plasma with microsecond pulsed electric fields effectively activates platelets and induces similar or higher growth factor release compared to traditional bovine thrombin, suggesting a potential clinical use that may be more cost-effective and practical.
March 2026 in “Preprints.org” This review of robotic systems in aesthetic plastic surgery found they offer precision and minimally invasive access, but their adoption is limited by high costs and technological limitations; further research is needed for standardization and wider application.
August 2015 in “Free Radical Biology and Medicine” Some treatments can improve skin's defense against damage, but overuse may cause other skin problems.
August 2015 in “Free Radical Biology and Medicine” This study explores the correlation between sirtuins' expression, histone deacetylation, and redox status in young and old monozygotic twins to understand their role in age-related mechanisms.
August 2015 in “Free Radical Biology and Medicine” This study found that Nrf2 activation protected keratinocytes from UVB damage but also caused thickening, inflammation, and cysts, limiting its therapeutic potential for skin protection.
2 citations
,
November 2024 in “Journal of Nonlinear Science” In this study, researchers found that the shape of polygonal domains, such as squares and triangles, significantly impacts Turing pattern formation, with domain geometry affecting the stability and type of bifurcations observed in simulations.
29 citations
,
February 2017 in “International Journal of Women's Dermatology” This article provides an endocrine perspective on evaluating and managing hirsutism but reports no new research findings.
8 citations
,
March 2020 in “Frontiers in Cell and Developmental Biology” This study developed a DPC cell line by introducing mutant CDK4, Cyclin D1, and TERT, making it a promising tool to study downstream signaling pathways activated by testosterone in androgenetic alopecia.
4 citations
,
July 2022 in “International Journal of Health Sciences” This review discusses rosemary's potential health benefits, including improved scalp circulation and skin protection, but reports no new clinical findings and highlights the need for better regulation and safety data on herbal medicines.
105 citations
,
February 2017 in “British Journal of Dermatology” This review discusses the range of long-term complications, including mucocutaneous, ocular, and psychological sequelae, for survivors of Stevens–Johnson syndrome and toxic epidermal necrolysis, but reports no new clinical results.
20 citations
,
January 2003 in “Chemical and Pharmaceutical Bulletin” This study reports that five new progesterone derivatives demonstrated inhibitory activity against the 5α-reductase enzyme and binding affinity for the androgen receptor in an in vitro hamster model.
20 citations
,
September 1978 in “International Journal of Dermatology” Hair growth is influenced by factors like genetics and nutrition, and more research is needed to understand hair loss and growth mechanisms.
13 citations
,
June 2024 in “Asian Pacific Journal of Cancer Prevention” The researchers reported that the ethyl ester group in YH239-EE may enhance its ability to induce cell death, making the (+) enantiomer a potentially promising therapy for breast cancer reflected in MCF7 cell studies.
February 2024 in “Planta” This study found that TRM21 acts as a positive regulator of flavonoid biosynthesis at the translational level in Arabidopsis, leading to changes in root hair growth and a decrease in flavonoid content when TRM21 is mutated.