April 2018 in “Journal of Investigative Dermatology” This study found that combining CelluTome system and RCM is a safe and effective protocol for evaluating wound healing responses in patients with epidermolysis bullosa.
September 2017 in “Journal of Investigative Dermatology” RCS-01 is safe and may help rejuvenate aging skin.
107 citations
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March 2014 in “BoneKEy Reports” This abstract reviews hereditary vitamin D-resistant rickets, a rare genetic condition causing severe early childhood rickets, and reports no new results; effective treatment typically requires high doses of calcium to address hypocalcemia and secondary hyperparathyroidism.
April 2018 in “Journal of Investigative Dermatology” This study found that treating human dermal fibroblast cells with ginsenoside Rd increased the expression of mRNA associated with the dermal-epidermal junction, suggesting potential as an anti-aging cosmetic ingredient.
31 citations
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August 2005 in “The American Journal of Dermatopathology” This study investigated the histopathology of ectodermal dysplasia/skin fragility syndrome, identifying specific skin and hair abnormalities associated with PKP1 gene mutations in two young female patients.
3 citations
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August 2017 in “Clinical case reports” A rare skin condition causes red and dark patches on the face and limbs.
In this study, researchers observed that oncogenic HrasG12V in single murine epidermal cells leads to an initial increase in progenitor cell renewal, but ultimately results in balanced cell fate choices that limit clone growth.
February 2009 in “Journal of The American Academy of Dermatology” The document concludes that detailed clinical descriptions of seven family cases help understand dominant dystrophic epidermolysis bullosa's symptoms and inheritance.
90 citations
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October 1998 in “Animal Reproduction Science” This study found that in captive mouflon rams, reproductive and physical maturation, marked by changes in hormone levels and physical attributes, progresses gradually across their life span, with sexual maturity tied closely to physical maturity.
25 citations
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November 2018 in “Cell reports” This study found that the ablation of Esrp1 and Esrp2 disrupts epithelial tight junctions by affecting Arhgef11 isoform expressions, highlighting a potential mechanistic link between splicing alterations and epithelial barrier defects.
This case report details a 17-year-old boy diagnosed with atypical juvenile pityriasis rubra pilaris (type 5) after presenting with persistent itchy skin lesions since age seven.
46 citations
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May 2021 in “Stem Cell Research & Therapy” This study found that strontium ranelate promotes cartilage regeneration in rats by enhancing chondrogenic differentiation of bone mesenchymal stem cells while inhibiting the Wnt/β-catenin signaling pathway.
15 citations
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December 2014 in “PLoS ONE” This study identifies iRhom2 as a crucial regulator of hair follicle differentiation, showing that the iRhom2Uncv mutation leads to dysplasia and reduced TACE maturation, resulting in a hairless phenotype in mice.
This study developed a sensitive method for assessing hair keratin stretch elasticity modulus, suggesting potential applications in forensic medicine.
April 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This research presents the Dodatek A model, elaborating on androgen function through new mathematical indices and methodological improvements, shifting focus from serum hormone concentrations to system interactions to better describe androgen activity comprehensively.
20 citations
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November 2003 in “American Journal Of Pathology” Fibroblasts from healthy donors can prevent changes seen in recessive epidermolysis bullosa simplex.
12 citations
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September 2020 in “JAMA Dermatology” This article reviews the clinical features and associated medical diagnoses of pityriasis rubra pilaris, noting incomplete information on disease prevalence and related conditions but offering no new clinical findings.
15 citations
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January 2012 in “Journal of Veterinary Science” This study examined variations in epidermal thickness and protein expression across different dog breeds, finding significant differences by anatomical site and breed, with associated mRNA and protein expression changes observed.
January 2009 in “한국피부장벽학회지” This study reports that in mice, CaR plays a critical role in sensing the epidermal Ca2+ gradient, influencing keratinocyte differentiation, and affecting epidermal development.
82 citations
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March 2013 in “PLoS ONE” In this study, vemurafenib was associated with a wide range of cutaneous side effects in patients with advanced melanoma, including photosensitivity and various skin and hair changes, necessitating regular dermatological management.
63 citations
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March 2018 in “Experimental Dermatology” This review explores the physiological roles of collagen XVII in the epidermis, its involvement in stem cell maintenance, and its connections with signaling pathways, but it reports no new results.
January 2026 in “Frontiers in biomedical technologies” In this study, high-resolution ultrasound imaging revealed that DHT administration in male C57BL/6 mice leads to increased epidermal and dermal thicknesses and decreased skin elasticity, simulating structural changes associated with Androgenetic Alopecia.
November 2022 in “Journal of Investigative Dermatology” This study identified 15 Iranian patients with PLEC variants linked to various plectinopathies and highlighted a novel association between a homozygous nonsense variant in PLEC and a rare combination of disorders including EB pruriginosa, muscular dystrophy, and congenital myasthenic syndrome.
In this study, researchers developed a method using stencils to create controlled stiffness gradients in alginate hydrogels, revealing that stiffer regions within the gels promote deeper invasion by breast cancer cells, facilitating the study of mechanosensitive cellular behaviors.
In this study of mouse hair follicles, Raptor was specifically expressed in hair follicle stem cells, while Rictor was mainly found in inner root sheath cells, indicating distinct roles in hair growth stages.
May 2006 in “The American journal of medicine” This article presents a case of a 45-year-old African American man with firm, hyperpigmented papules and pustules on his cheeks and neck, persisting despite various shaving methods.
May 2026 in “Journal of the Egyptian Womenʼs Dermatologic Society” This review discusses microneedling radiofrequency in cosmetic dermatology, particularly for skin texture improvement and various conditions, and reports no new clinical results.
1 citations
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January 2008 in “touchREVIEWS in Endocrinology” Generalized glucocorticoid resistance causes hormone imbalances and varied symptoms due to gene mutations.
July 2022 in “Journal of Investigative Dermatology” This study found that the KrasG12D mutation alters ERK signal dynamics in hair follicle stem cells, leading to tissue deformation, and suggests a collective effect of mutant cells is necessary for disruption.
September 2023 in “Journal of the American Academy of Dermatology”