Characterizing Disease Features and Other Medical Diagnoses in Patients With Pityriasis Rubra Pilaris

    September 2020 in “ JAMA Dermatology
    Katherine Halper, Benjamín Wright, Nolan J. Maloney, Mindy M. Kim, Vignesh Ravi, Scott Worswick, Donald Lei
    TLDR PRP patients show varied symptoms and need more research to understand related conditions.
    The study on Pityriasis Rubra Pilaris (PRP) aimed to characterize the disease features and associated medical diagnoses in patients. PRP is a rare disorder marked by hyperkeratotic follicular papules, scaling erythematous plaques, and palmoplantar keratoderma, with significant variability in clinical presentation. Not all patients progress to erythroderma, and some may develop seronegative arthritis. The prevalence of arthropathy, alopecia, anhidrosis, and other medical conditions in PRP patients was not well-documented, highlighting the need for further research to better understand these associations.
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