12 citations,
September 2020 in “JAMA Dermatology” The study on Pityriasis Rubra Pilaris (PRP) aimed to characterize the disease features and associated medical diagnoses in patients. PRP is a rare disorder marked by hyperkeratotic follicular papules, scaling erythematous plaques, and palmoplantar keratoderma, with significant variability in clinical presentation. Not all patients progress to erythroderma, and some may develop seronegative arthritis. The prevalence of arthropathy, alopecia, anhidrosis, and other medical conditions in PRP patients was not well-documented, highlighting the need for further research to better understand these associations.
1 citations,
December 2023 in “Curēus” Most children with a common hemochromatosis genotype had elevated iron levels but no severe symptoms.
1 citations,
October 2022 in “Rheumatology” Juvenile RHUPUS syndrome, a rare overlap of rheumatoid arthritis and systemic lupus erythematosus (SLE) in children, is underdiagnosed and not well understood. This case report describes an 11-year-old girl with polyarthritis deformans, profound asthenia, recurrent oral aphtosis, and massive hair loss. Diagnostic criteria for SLE and juvenile idiopathic arthritis (JIA) were met, with positive rheumatoid factor (RF), antinuclear antibodies (ANA), and anti-Sm antibodies. She was treated with methotrexate and hydroxychloroquine. The case highlights the importance of considering RHUPUS in pediatric patients with deforming arthropathy, despite its rarity.
97 citations,
October 2019 in “Journal of Translational Medicine” A very low-calorie ketogenic diet is effective for quick weight loss and improving health in obese patients, with careful management of side effects and maintenance.
6 citations,
May 1987 in “Acta dermato-venereologica” Syphilis patients showed abnormal hair root changes, with no difference between primary and secondary stages.