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    Glossary Keratoderma

    thickening of skin on palms and soles

    Keratoderma refers to a group of skin conditions characterized by the thickening of the outer layer of the skin, particularly on the palms of the hands and the soles of the feet. This thickening is due to an overproduction of keratin, a key structural protein in the skin. It can be inherited or acquired and may be associated with other medical conditions.

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    1. Structural and biochemical changes underlying a keratoderma-like phenotype in mice lacking suprabasal AP1 transcription factor function Cell Death and Disease · 2015 · 17 citations
    2. Spiny keratoderma ‐ a demonstration of hair keratin and hair type keratinization Journal of Cutaneous Pathology · 1999 · 30 citations
    3. Recessive Mutation in FAM83G Associated with Palmoplantar Keratoderma and Exuberant Scalp Hair Journal of Investigative Dermatology · 2017 · 10 citations
    4. Biallelic Variants in Lanosterol Synthase (LSS) Cause Palmoplantar Keratoderma-Congenital Alopecia Syndrome Type 2 2022 · 8 citations
    5. Resolution of pseudoainhum with acitretin therapy in a patient with palmoplantar keratoderma and congenital alopecia JAAD case reports · 2019 · 6 citations
    6. RSPO1-mutated keratinocytes from palmoplantar keratoderma display impaired differentiation, alteration of cell–cell adhesion, EMT-like phenotype and invasiveness properties: implications for squamous cell carcinoma susceptibility in patients with 46XX disorder of sexual development Orphanet journal of rare diseases · 2022 · 5 citations
    7. DSP c.6310delA p.(Thr2104Glnfs*12) associates with arrhythmogenic cardiomyopathy, increased trabeculation, curly hair, and palmoplantar keratoderma Frontiers in Cardiovascular Medicine · 2023 · 1 citations
    8. Ichthyosis follicularis with alopecia and photophobia syndrome with coexisting palmoplantar keratoderma treated with acitretin International journal of trichology · 2022 · 1 citations
    9. WOOLY HAIR PALMOPLANTAR KERATODERMA : A CASE REPORT International Journal of Advanced Research · 2024
    10. Spiny Keratoderma 2021
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