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Aging mice have slower hair regeneration due to changes in signal balance, but the environment, not stem cell loss, controls this, suggesting treatments could focus on environmental factors.

LGR5 helps maintain corneal cell characteristics and prevents unwanted changes by controlling specific cell signaling pathways.

Mice lacking a key DNA methylation enzyme in skin cells have a lower chance of activating stem cells necessary for hair growth, leading to progressive hair loss.

TRH stimulates human hair growth and extends the hair growth phase.

Minoxidil and finasteride treat hair loss; more research needed for other options.

mTOR signaling helps activate hair stem cells by balancing out the suppression caused by BMP during hair growth.

Human hair follicles produce and respond to erythropoietin, helping protect against stress.

Blue light promotes hair growth by interacting with specific receptors in hair follicles.

Keratin proteins are crucial for healthy skin, but mutations can cause skin disorders with no effective treatments yet.

The FOXN1 gene is crucial for developing immune cells and preventing immune disorders.

Air pollution (PM10) increases skin inflammation and aging by reducing collagen and may trigger a repair response in skin cells.

Tiny needles with valproic acid can effectively regrow hair.

Oestrogens help maintain healthy skin, heal wounds, and may protect against skin aging and cancer.

Beta-caryophyllene helps improve wound healing in mice, especially in females.

Inactive hair follicle stem cells help prevent skin cancer.

Certain bacteria and fungi are linked to healthy scalps and dandruff, suggesting that the scalp's microbial balance affects its health.

Brain-Derived Neurotrophic Factor (BDNF) slows down hair growth and promotes hair follicle regression.

The transscrotal testosterone patch normalizes hormone levels in men with AIDS and weight loss but does not improve weight, body mass, or quality of life.

Technique creates 3D cell spheroids for hair-follicle regeneration.

Light can turn on hair growth cells through a nerve path starting in the eyes.

Wnt1a-conditioned medium from stem cells helps activate cells important for hair growth and can promote hair regrowth.

RTA 408 cream protects mice from radiation skin damage.

Fat from the body can help improve hair growth and scars when used in skin treatments.

Nanotechnology in dermatology shows promise for better drug delivery and treatment effectiveness but requires more safety research.

A position effect on the TRPS1 gene causes excessive hair growth in humans and mice.

The document concludes that targeting 5α-reductase, the androgen receptor, and hair growth genes, along with using compounds with anti-androgenic properties, could lead to more effective hair loss treatments.

Both mouse and rat models are effective for testing alopecia areata treatments.

Products should be called 'sperm-safe' only after thorough, well-designed tests.

Obese women with PCOS show a male-like pattern in certain fat tissue gene expressions.

Photothermal hydrogels are promising for infection control and tissue repair, and combining them with other treatments could improve results and lower costs.