Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

In this study, the researchers reported that NMMHC IIA dissociates from PAR1 and activates the CREB3/ARF4 pathway, worsening thrombin-induced blood-brain barrier damage, suggesting it as a potential therapeutic target for blood-brain barrier-related diseases.

In this case report, the authors suggest that methotrexate-induced rheumatoid papular eruption is a rare side effect of methotrexate, resolved after discontinuation, which may be linked to rheumatic conditions.

This article discusses the evaluation of minimal residual disease in childhood acute lymphoblastic leukemia using molecular methods and reports no new findings.

This study proposes a new mathematical model, the Harmonic Mean equation, for precisely quantifying nuclear pleomorphism in breast cancer grading, showing high performance with accuracy, recall, specificity, precision, and F1-score metrics.

This review discusses the neuroprotective potential of formononetin, especially for neurological diseases, and reports no clinical results; the authors suggest its promise for developing central nervous system drugs.

This study found that topical treatment with Maneb led to delayed epithelial cell degeneration in hair follicles of rats due to apoptosis.

In this study, baseline neutrophil-to-lymphocyte ratio (NLR) was associated with predicting early trichoscopic response in patients undergoing PRP-based treatment for non-scarring alopecia.

This study demonstrated that the FER/MLO signaling module regulates calcium dynamics and ROS accumulation in root hair growth, with the constitutively active MLO (faNTA) able to restore normal development and signaling in specific mutant genotypes, highlighting MLO15's role in root hair tip growth regulation.

This case report describes a young girl with a rare association of anti-SRP positive necrotizing autoimmune myopathy and systemic lupus erythematosus, who responded well to corticosteroid treatment.

This case report documented the management of a 46-year-old female with Marine-Lenhart syndrome, combining antithyroids with minimally invasive sclerotherapy to achieve euthyroidism and reduce thyroid nodule size by 58%.

This study found that among mixed connective tissue disease patients in a tertiary care hospital in Pakistan, Raynaud phenomenon was the most common clinical feature, present in 80% of patients.

This study found that RNase L acts as a regeneration repressor gene in mammals, as seen in Rnasel-/- mice which showed increased regenerative capacity and elevated Wound Induced Hair Neogenesis through enhanced IL-36α signaling, suggesting a tradeoff between regeneration and immune regulation.

This review describes the clinical presentation, diagnosis, and management of adrenomyeloneuropathy, including rehabilitative therapies and spasticity management, and reports no new clinical results.

In this descriptive research conducted in Tirunelveli City, Tamil Nadu, the study identified common health problems among radiographers, including tiredness, body pain, and emotional disturbances, highlighting the need to address these issues to ensure accurate disease diagnosis and treatment in healthcare settings.

This meta-analysis found that rheumatoid arthritis patients experience poorer sleep quality compared to healthy controls, including reduced total sleep time and efficiency, longer sleep latency, and increased wakefulness after sleep onset.

This study found that among Indian rheumatoid arthritis patients, the MTHFR A1298C polymorphism was associated with varying responses to methotrexate, with 1298CC genotypes showing higher toxicity and poorer efficacy compared to 1298AA genotypes.

This study found that acanthosis nigricans in the knuckles correlates with higher insulin and HOMA-IR values, potentially serving as an early, accessible marker for insulin resistance even without excess weight.

This study found that methotrexate, when administered according to current recommendations, effectively manages rheumatoid arthritis for many patients in Poland, although regular monitoring is necessary due to possible adverse effects.

This study reports that the DMI3 gene, essential for nodule formation in legume-rhizobial symbiosis, encodes a calcium/calmodulin-dependent protein kinase, highlighting its role in multiple plant symbioses.

This study found that RCM combined with dermoscopy can differentiate disease states between alopecia areata, tinea capitis, nevus sebaceous, and linear scleroderma of the scalp by identifying distinct dermal and follicular patterns.

This article reviews the multifunctional roles of calreticulin outside the ER and highlights its impact on wound healing in animal models, but reports no new clinical results.

This medical case report describes a 69-year-old man's diagnosis and management of ANCA-associated vasculitis leading to rapidly progressive glomerulonephritis, ultimately treated with glucocorticoids and rituximab.

In this study, researchers identified known and novel miRNAs in Liaoning Cashmere goat skin and found differences in miRNA expression linked to cashmere fineness, providing new insights into LCG goat skin biology.

This study investigated a patient with spinal and bulbar muscular atrophy who had 68 CAG repeats, revealing early onset and unique symptoms not previously documented in the condition.

This case report describes a 65-year-old man diagnosed with atraumatic splenic rupture, which is rare and can occur without trauma, following sudden-onset left-sided abdominal pain.

This research highlights the potential of non-coding RNAs as biomarkers and therapeutic targets in dermatology, while experimental studies on a unique GVM case suggest CCM2L may modulate disease severity, advancing understanding of genetic mechanisms in rare skin disorders.

This study reported two cases of ryzophagia among nonpregnant women in the US, with symptoms resolving after iron dextran therapy, suggesting a link with iron deficiency.

This study found that in patients with elevated fibrinogen levels undergoing revision rhinoplasty, PDRN decreased M1 cytokines and increased M2 cytokines, potentially offering a new therapeutic approach, but further research is needed to understand its mechanisms and effects fully.

This study found that overexpression of the mineralocorticoid receptor in a mouse model led to premature epidermal barrier development, keratinocyte apoptosis, and postnatal alopecia, indicating new roles for MR signaling in skin physiology.

This case report details a patient with myasthenia gravis and a malignant thymoma whose rising liver function tests, initially thought to be related to antibiotic use, were ultimately attributed to thymoma-associated multiorgan autoimmunity.