December 2007 in “Röntgenpraxis” This review discusses various treatments for androgenic alopecia, highlighting FDA-approved options and other commonly used therapies, but reports no new clinical results.
September 1999 in “The Journal of The British Menopause Society” This review discusses how menopause and hormone replacement therapy affect skin aging in women but reports no new clinical findings.
184 citations
,
October 2007 in “Proceedings of the National Academy of Sciences of the United States of America” This study found that sulforaphane-rich broccoli sprout extracts reduced UV-induced erythema by 37.7% in humans, suggesting a protective strategy against UVR damage.
158 citations
,
January 2015 in “Artificial Intelligence in Medicine” This study found that DrugNet, a network-based prioritization method, effectively improves drug repositioning tasks, achieving high performance in validation tests and clinical trial comparisons.
120 citations
,
October 2007 in “Clinical Interventions in Aging” This review discusses the effects of estrogens on skin aging and highlights the potential benefits of estrogen replacement therapy and selective estrogen receptor modulators for improving skin health in postmenopausal women, but reports no new clinical findings.
117 citations
,
February 2017 in “American Journal of Clinical Dermatology” This systematic review concluded that the support for using spironolactone at commonly prescribed doses is based on evidence of limited quality.
117 citations
,
August 2008 in “Sociology of Health and Illness” This review analyzes how the pharmaceutical industry's emphasis on lifestyle drugs and marketing practices leads to the integration of pharmaceuticals into everyday life, with a domestic focus and view of drugs as quick solutions.
82 citations
,
June 2020 in “Inflammation Research” This review discusses the complex pathophysiological and clinical aspects of COVID-19, including dermatological findings and their association with SARS-CoV-2 infection but reports no new clinical results.
68 citations
,
March 2019 in “Advanced Healthcare Materials” This review assesses the benefits and limitations of various supramolecular hydrogels, including polymeric and peptide-based types, for wound healing, but reports no new clinical results.
67 citations
,
May 2018 in “Journal of Ginseng Research” This paper highlights the need for a comprehensive red ginseng monograph to provide standardized information on its components, certified functionality, efficacy, action mechanisms, and safety, especially given its widespread use as a health functional food in South Korea and interest in its benefits worldwide.
67 citations
,
January 2012 in “Biological and Pharmaceutical Bulletin” This study found that nanoparticles did not permeate intact rat skin but could penetrate skin that had been artificially punctured, primarily through grooves or hair follicles.
57 citations
,
July 2018 in “Scientific Reports” This study found that prevascularizing dermal matrices with adipose tissue-derived microvascular fragments improved vascularization and allowed earlier successful skin grafting in a bradythrophic wound model.
53 citations
,
March 2010 in “British Journal of Dermatology” This study found that androgenetic alopecia is the leading cause of hair loss in adolescents and may indicate endocrine disorders, emphasizing the need for accurate diagnosis.
47 citations
,
January 2013 in “International Journal of Cosmetic Science” This review explores genetic and lifestyle factors influencing hair diversity and reports no new findings, calling attention to the potential for future discoveries in genetic and epigenetic research.
47 citations
,
July 2005 in “British Journal of Dermatology” This study found no protective effect of topical calcipotriol on hair loss in chemotherapy patients, and the authors propose the term "atrophic telogen effluvium" for this type of hair loss.
43 citations
,
July 2018 in “Journal of The European Academy of Dermatology and Venereology” This study found that a topical solution combining 0.25% finasteride with 3% minoxidil significantly improved hair growth, as measured by hair density, diameter, and global assessment, in men with androgenetic alopecia, compared to 3% minoxidil alone, over 24 weeks without systemic adverse effects reported.
43 citations
,
May 1986 in “Clinics in Endocrinology and Metabolism” This review examines androgen status in male and female obesity and its influence on the metabolic syndrome, but reports no new clinical results.
39 citations
,
May 2014 in “Frontiers in Pharmacology” In this study, CD4+CD25+FoxP3+ Regulatory T cells were found to reduce TGF-b1 induced lung fibrosis and fibrocyte accumulation in mice, partly by suppressing fibroblast growth factor 9.
36 citations
,
July 2019 in “Journal of Materials Science Materials in Medicine” This study demonstrated that keratin derived from human hair can improve axon extension and alleviate motor deficits from sciatic nerve injuries, highlighting its potential as a promising biomaterial for peripheral nerve regeneration.
36 citations
,
November 2006 in “Medical Care Research and Review” This review covers the ongoing debate on measuring underinsurance in health coverage and reports no new empirical results, recommending a national effort to standardize underinsurance metrics.
34 citations
,
October 2021 in “Scientific Reports” This study found that nobiletin-loaded vesicles effectively restored skin condition in a mouse model of skin cancer, suggesting they are a promising treatment delivery system.
34 citations
,
January 2020 in “IEEE Access” This study reported that the PM-DBiGRU model enhances aspect-level sentiment classification in drug reviews, outperforming existing methods on the newly proposed SentiDrugs dataset.
31 citations
,
January 2014 in “Journal of endocrinological investigation” This study reviewed Woodhouse-Sakati syndrome and found it consistently associated with hypogonadism, decreased IGF1, and frontotemporal alopecia, with additional symptoms like intellectual disabilities and diabetes in some patients.
31 citations
,
May 2012 in “European Journal of Dermatology” This review examines hair and skin disorders in post-menopausal women and notes a lack of evidence supporting specific treatments for this population.
29 citations
,
September 2014 in “Current Opinion in Endocrinology, Diabetes and Obesity” This review discusses the efficacy and safety of 5-alpha reductase inhibitors for treating androgenetic alopecia, noting concerns about sexual side effects, which are typically uncommon and often resolve over time.
28 citations
,
March 2019 in “Journal of Dermatological Science” This review discusses methods for evaluating hair growth-promoting effects of candidate substances for androgenetic alopecia, focusing on cell assays, organ cultures, and animal models, and reports no new results.
28 citations
,
January 2003 in “Urologic oncology” This review discusses the hormonal influences on prostate carcinogenesis and notes ongoing trials investigating whether finasteride could reduce prostate cancer incidence by inhibiting dihydrotestosterone synthesis, but it reports no new results.
26 citations
,
January 2013 in “BioMed Research International” This review discusses the hormonal influences on hair cycling disorders in post-partum and postmenopausal women and notes the lack of evidence for effective targeted treatments.
24 citations
,
March 2011 in “British Journal of Dermatology” This study found evidence of increased DNA methylation of the androgen receptor gene in occipital hair follicles from men with androgenetic alopecia.
24 citations
,
November 1978 in “Biochemistry” This paper reports on the structural characteristics of α-type filaments in the inner root sheath cells of guinea pig hair follicles without presenting new clinical findings.