research Can the Second to Fourth Digit Ratio (2D:4D) Be a Marker to Determine Ankylosing Spondylitis Disease Activity?
The index to ring finger ratio may indicate disease severity in female ankylosing spondylitis patients, but not in males.
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research Strategies for the Synthesis of Heterocycles and Their Applications
Methods for creating diverse ring-shaped molecules and their uses.
research Centrifugal Lipodystrophy of the Scalp Manifesting as Centrifugal Lipodystrophic Alopecia
Reversible hair loss in a ring pattern on the scalp may be linked to changes in leptin levels in fat tissue.
research The Clinical Differences in 2:4 Finger Ratios of Hirsute Women
Women with excessive hair growth tend to have shorter index and ring fingers compared to others.
research Anesthesia Techniques For Harvesting Via Follicular Unit Excision
Local anesthesia, often with sedation, effectively reduces pain in hair transplant harvesting.
research Anesthetics Prior to Keloid Injections: A Painless Approach
Using lidocaine before keloid injections makes the treatment more comfortable for patients.
research Androgen Binding Profiles of Two Distinct Nuclear Androgen Receptors in Atlantic Croaker (Micropogonias Undulatus)
Different types of androgens bind differently to two receptors, AR1 and AR2, in Atlantic croaker's brain and ovarian tissues, suggesting these receptors may control different androgen actions in fish.
research Combined Hormonal Contraception and Venous Thromboembolism
Birth control pills increase the risk of blood clots, especially within the first year and with certain types.
research Minimum Structural Requirements for Minoxidil Inhibition of Lysyl Hydroxylase in Cultured Fibroblasts
Minoxidil needs specific structure to block lysyl hydroxylase; exploring alternatives may keep benefits without this effect.
research Piecing Together the Pigment-Type Switching Puzzle
The document concludes that MGRN1 affects mouse fur color by interfering with a receptor's signaling, but its full role in the body is still unknown.
![Synthesis and In Vitro Study of 17β-[N-Ureylene-N,N′-Disubstituted]-4-Methyl-4-Aza-5α-Androstan-3-Ones as Selective Inhibitors of Type I 5α-Reductase](/images/research/d19df8a7-8de6-4430-8a0d-4ffa1f502985/small/15608.jpg)
research Synthesis and In Vitro Study of 17β-[N-Ureylene-N,N′-Disubstituted]-4-Methyl-4-Aza-5α-Androstan-3-Ones as Selective Inhibitors of Type I 5α-Reductase
New compounds were made that effectively block a specific enzyme related to androgen conditions.
research Alternative Synthesis of the Anti-Baldness Compound RU58841
A new, less toxic and more efficient method to create the anti-baldness compound RU58841 was developed in 2014.
research Histopathological and Dermoscopic Correlations in Pityriasis Versicolor
Dermoscopic and histopathological features combined can help diagnose Pityriasis versicolor.
research Structural Requirements of Minoxidil Analogs for Enhancing Lysyl Hydroxylase Inhibitory Activity
Minoxidil analogs can be improved for hair growth inhibition by modifying specific parts of their structure.
research Basics of Hormonal Contraception
Hormonal contraceptives are effective for teens but require careful consideration of side effects and individual health.
research 2-Substituted 4-(Thio)chromenone 6-O-Sulfamates: Potent Inhibitors of Human Steroid Sulfatase
New compounds were made that block an enzyme linked to breast cancer better than existing treatments.
research Non-Invasive Quick Diagnosis of Cardiovascular Problems from Visible and Invisible Abnormal Changes with Increased Cardiac Troponin I Appearing on Cardiovascular Representation Areas of the Eyebrows, Left Upper Lip, etc. of the Face and Hands: Beneficial Manual Stimulation of Hands for Acute Anginal Chest Pain, and Important Factors in Safe, Effective Treatment
Visible and invisible changes on the face and hands can indicate heart problems, and manual hand stimulation can relieve chest pain.
research AKR1D1 Regulates Glucocorticoid Availability and Glucocorticoid Receptor Activation in Human Hepatoma Cells
AKR1D1 controls glucocorticoid levels and receptor activity in liver cells.
research Synthesis and Pharmacological Properties of Heterocyclic Steroids
The document concludes that scientists created various steroids with different properties, including a more effective semi-synthetic vitamin D.
research Diagnosis of Breast Cancer by X-Ray Diffraction of Hair
X-ray diffraction of hair might help detect breast cancer non-invasively.
research The Use of 2D:4D Digit Ratio as a Predictor of Androgenetic Alopecia: A Review
Finger length ratios might help predict common hair loss.
research Analysis of Skin Microbiota from Canine Dermatitis in Odisha
Young dogs in Odisha with dermatitis are most often infected by Microsporum fungus, and Miconazole is the most effective treatment.
research The Association Between Male Pattern Baldness and Second to Fourth Finger Ratio with Prostate Cancer: A Prospective Cohort Study
Male pattern baldness may predict prostate cancer risk.
research 17α-Acetoxy-6-Bromo-16β-Methylpregna-4,6-Diene-3,20-Dione: A New Steroidal Derivative with High Antiandrogenic Activity
A new compound with strong antiandrogenic effects was found, potentially useful for treating conditions like acne and prostate cancer.
research A Review of Coumarin Derivatives in Pharmacotherapy of Breast Cancer
Coumarin derivatives show promise as anti-estrogenic agents for treating breast cancer, with some in clinical trials.
research Nonsteroidal Inhibitors of Human Type I Steroid 5α-Reductase
New compounds called benzoquinolinones may treat conditions linked to excess DHT.
research Hair Regrowth in Alopecia Areata Patients Following Stem Cell Educator Therapy
Stem Cell Educator therapy helps regrow hair and improve life quality in alopecia areata patients.
![Benzo[c]quinolizin-3-ones: A Novel Class of Potent and Selective Nonsteroidal Inhibitors of Human Steroid 5α-Reductase 1](/images/research/ff6e6cbe-cb9c-4d11-87ef-671d28ffd4fa/small/15506.jpg)
research Benzo[c]quinolizin-3-ones: A Novel Class of Potent and Selective Nonsteroidal Inhibitors of Human Steroid 5α-Reductase 1
Benzo[c]quinolizin-3-ones are effective nonsteroidal inhibitors of human steroid 5α-reductase 1.
research Review Paper: The Use of Reflectance Confocal Microscopy in Selected Inflammatory Skin Diseases
Reflectance confocal microscopy is a useful, non-invasive tool for diagnosing some skin diseases, with potential for future improvements.
research Molecular Docking Studies and ADME Prediction of Novel Isatin Analogs with Potent Anti-EGFR Activity
Some new isatin compounds could be strong cancer-fighting drugs because they fit well in cancer-related proteins and have good drug-like properties.