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The guidelines advise against using testosterone and DHEA in women for most conditions due to safety and effectiveness concerns, but suggest considering testosterone for postmenopausal women with low sexual desire.

The document concludes that the fast-growing direct-to-consumer genetic testing market lacks sufficient regulation, posing risks to consumers due to questionable test quality and accuracy.

The method can effectively extract biomedical information without needing expert annotation, performing better than previous models.

Acne affects most teenagers and can continue into adulthood, with various treatments available that show improvement but have concerns like antibiotic resistance and side effects.

Melatonin may help with sleep issues, depression, and cancer, but more research is needed.

Biomaterials with MSC-derived substances could improve tissue repair and have advantages over direct cell therapy.

Testing basal 17-HP levels is a good way to screen for nonclassic adrenal hyperplasia in women with high androgen levels.

Telogen effluvium is a reversible hair loss condition that requires a detailed diagnosis and often resolves on its own.

The skin is a complex barrier for drug penetration, but understanding its structure and interactions can improve drug delivery methods.

Lifestyle changes can improve body composition, excess male hormone levels, and insulin resistance in women with PCOS.

Dutasteride and finasteride may reduce sperm count and volume but don't affect movement or shape; effects are reversible after stopping.

Metformin is effective for treating excessive hair growth in women with PCOS and may work better than the standard treatment in some ways.

Targeted cancer therapies often cause serious skin problems that need careful management.

Some herbal therapies may help with skin conditions, but more research is needed to confirm their safety and effectiveness.

The document concludes that developing generic topical drugs requires ensuring they match the original in quality, composition, and structure, and often involves complex testing and regulatory steps.

Researchers found 19 genes important for root hair growth in a plant called Arabidopsis.

The PDGF/PDGFR pathway is a potential drug target with mixed success in treating various diseases, including some cancers and fibrosis.

Hormone treatments in transsexual individuals reduce hair growth and oil production in male-to-females and increase them in female-to-males.

Alopecia areata involves immune activation in the scalp, suggesting treatments targeting TH1, TH2, and IL-23 pathways.

Chemotherapy can cause skin problems like hair loss, mouth sores, and skin darkening, and recognizing these can affect treatment decisions.

Some medicinal plants can help heal wounds and may lead to new treatments.

Lower doses of treatments for hirsutism and acne in PCOS are effective and cause fewer side effects.

Myrtle has various health benefits and potential for medicine development.

Flutamide is more effective and has fewer side effects than spironolactone for treating hirsutism.

People who are more materialistic often expect life changes from buying things, leading to more debt and credit misuse.

Women with PCOS face higher risks of diabetes and heart disease, and these risks increase with obesity.

HairMax LaserComb® effectively promotes hair growth and stops hair loss in males with androgenetic alopecia, with no serious side effects.

DrugNet effectively identifies new uses for existing drugs and may save resources in drug development.

The document concludes that recognizing and treating cutaneous lupus erythematosus early is crucial for managing the skin and potential systemic symptoms.

Dermatoscopy and videodermatoscopy are useful for diagnosing and monitoring various skin, hair, and nail conditions.