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Mutations in the hairless gene in mice affect its expression and lead to a range of developmental issues in multiple tissues.

Oral retinoids are effective for severe skin conditions but require careful use due to side effects.

Hair loss treatments include medications and new methods like low-level light therapy, which may work by boosting cell activity and blood flow.

The enzyme 17β-HSD type 2 mainly performs oxidation in human sebaceous glands, which may help protect against acne.

Hidradenitis suppurativa may be related to hormones and patients often have metabolic disorders; more research is needed to understand this connection.

Some drugs can cause hair loss, excessive growth, or color changes, often reversible but sometimes permanent.

Plant-based ingredients are effective and safe for modern skincare products.

New sulfur-containing steroid analogs show promise for more targeted medical treatments.

Androgens like testosterone are important hormones for both men and women, made differently in each sex and affecting the body by regulating genes and quick interactions with cell components.

Zinc can help with some skin problems, but its effectiveness varies depending on the condition.

Patient-derived melanocytes can potentially treat vitiligo by restoring skin pigmentation.

Lower CD200R1 on certain immune cells is linked to more severe rheumatoid arthritis and immune imbalance.

The document concludes that new treatments are needed to better manage acne and reduce side effects related to current therapies.

Meis1 is crucial for skin health and tumor development.

Certain microRNAs are linked to various skin diseases and could be used to diagnose and treat these conditions.

Zinc can be a helpful secondary treatment for certain skin conditions, but more research is needed to guide its use.

Researchers found new genes involved in hair growth, which could help develop new hair treatments.

The study found no common cause for a girl's crystalline cataract and uncombable hair, suggesting their co-occurrence might be coincidental.

Taking too many vitamin and mineral supplements can cause serious health problems.

Finasteride improves hair growth and reduces hirsutism in women, but side effects and optimal dosages need further research.

Androgens affect bone and fat cell development differently based on the cells' embryonic origin.

Lack or blocking of SRD5a, a key component in hormone creation, can lead to conditions like pseudohermaphrodism and affect hair growth, bone mass, muscle strength, and reproductive health. More research is needed on its regulation from fertilization to adulthood.

The enzymes 5α-reductase and 3α/β-hydroxysteroid oxidoreductase help create brain-active substances from progesterone and testosterone, which could be used for treatment, but more research is needed to ensure their safety and effectiveness.

Melatonin-loaded nanocarriers improve melatonin delivery and effectiveness for various medical treatments.

The document concludes that oral finasteride and topical minoxidil are effective for genetic hair loss, while other treatments for different types of hair loss show promise but need more research.

Hormonal changes during and after pregnancy can cause hair growth changes and hair loss, with treatments available for some conditions.

RNA aptamers can specifically block FGF5-related cell growth, potentially treating related diseases or hair disorders.

Menopausal acne is treated with medications and lifestyle changes, but careful choice is needed due to side effects.

Liposomes improve the delivery and effectiveness of cosmetic ingredients but face challenges like cost and stability.

Stressed fibroblasts greatly increase melanin production in hair, skin, and eye cells, mainly due to a growth factor called bFGF.