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Older hair follicle stem cells have a reduced ability to renew themselves, leading to more hair loss.

Both Th1 and Th2 immune responses are increased in alopecia areata, with Th2 response more strongly linked to how severe the disease is.

Activating Nrf2 helps wounds heal faster by increasing hair follicle stem cells.

Topical tofacitinib is effective in promoting hair growth for non-scarring alopecia.

Some drugs can cause hair loss or growth, but hair usually returns to normal after stopping the drug.

The Rotterdam Study aims to understand disease causes in the elderly and has found new risk factors and genetic influences on various conditions.

The skin is a complex barrier for drug penetration, but understanding its structure and interactions can improve drug delivery methods.

The document concludes that developing generic topical drugs requires ensuring they match the original in quality, composition, and structure, and often involves complex testing and regulatory steps.

Adam10 enzyme is crucial for healthy skin and proper Notch signaling.

Eating disorders like anorexia and bulimia cause skin problems, and dermatologists can help detect these disorders early for better treatment outcomes.

Ruby laser pulses best destroy hair follicles during the growth phase and effectiveness varies with laser intensity; melanin is key for targeting, and timing treatments can improve results.

Voriconazole can cause serious side effects, especially in long-term use.

Nutraceuticals may improve skin health and protect against aging, but more research is needed on their optimal use and possible health risks.

Alpha-hydroxy acids, like glycolic acid, safely improve skin issues and work on all skin types.

Some drugs can cause hair loss, change hair color and shape, or increase hair growth, and treatment may involve stopping the drug or using specific hair growth treatments.

New genes and pathways are important for testosterone production and male sexual development.

Nanotechnology in dermatology shows promise for better drug delivery and treatment effectiveness but requires more safety research.

The new micelle formulation delivers acne treatment more effectively and safely than current gels.

Multiphoton microscopy is a promising tool for detailed skin imaging and could improve patient care if its challenges are addressed.

Noncoding dsRNA boosts hair growth by activating TLR3 and increasing retinoic acid.

The best way to treat acne is to prevent healthy skin glands from turning into acne lesions by controlling the triggers early on.

The enzyme 17β-HSD type 2 mainly performs oxidation in human sebaceous glands, which may help protect against acne.

Fractional laser resurfacing is effective and safe for skin treatment, with benefits like less downtime and a low risk of adverse events.

Eruptive vellus hair cysts are a cosmetic skin condition, more common in young adults, with few effective treatments.

Isotretinoin is safe and effective for acne, with common side effects like dry lips; serious side effects are rare.

Taking L-cystine and vitamin B6 can prevent hair loss caused by smoke in mice.

Some drugs can cause hair loss, excessive growth, or color changes, often reversible but sometimes permanent.

Some patients with mycosis fungoides or Sézary syndrome experience hair loss, which may be similar to alopecia areata or linked to skin lesions, possibly due to abnormal T cells, and bexarotene can help treat it.

A disease causing skin issues in young adult German short-haired pointers is hereditary, with most affected dogs not responding to treatment.

Single Blimp1+ cells can create functional sebaceous gland organoids in the lab.