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Human hair follicle organ culture is a useful model for hair research with potential for studying hair biology and testing treatments.

The article concludes that the wool follicle is a valuable model for studying tissue interactions and has potential for genetic improvements in wool production.

Hair ages due to genetics and environmental factors, leading to graying and thinning, with treatments available for some conditions.

Skin changes can help diagnose and manage endocrine disorders like thyroid problems, diabetes, and adrenal gland conditions.

The document concludes that alopecia areata is an autoimmune disease without a definitive cure, but treatments like corticosteroids are commonly used.

European guidelines recommend regular eye and ear exams, skin care, vitamin D supplements, and cautious use of medications for managing congenital ichthyoses.

The topical inhibitor CUR61414 was not effective in treating basal cell carcinoma in human trials.

Metabolic syndrome and PCOS are related but separate conditions, with metabolic syndrome increasing the risk of heart disease and diabetes.

Fat from the body can help improve hair growth and scars when used in skin treatments.

There are still challenges in diagnosing and treating chronic skin diseases, but there is hope for future improvements.

Targeting glucocorticoid action might help treat type-2 diabetes, but human trials are needed.

Finasteride increases hair density in female androgenetic alopecia, but individual results may vary.

Understanding the genetics of rare inherited ichthyosis syndromes is key for better treatments and genetic counseling.

The review suggests thorough evaluation and genetic testing for proper diagnosis and treatment of Chrousos syndrome.

Human hair follicles switch between active and resting phases unpredictably.

Women's hair generally gets thinner and less dense starting in their mid-thirties, with hair loss becoming more common as they age due to both genetics and environment.

Eating high glycemic foods and drinking milk may worsen acne by increasing insulin and IGF-1 levels.

Changing the amount of PLC5 in Arabidopsis affects root growth and drought resistance, with less PLC5 slowing root growth and more PLC5 improving drought tolerance but hindering root hair growth.

The TCL1 transgenic mouse model is useful for understanding human B-cell leukemia and testing new treatments.

Skin and hair can regenerate after injury due to changes in gene activity, with potential links to how cancer spreads. Future research should focus on how new hair follicles form and the processes that trigger their creation.

Loss of keratin K2 causes skin problems and inflammation.

Acne is significantly influenced by genetics, and understanding its genetic basis could lead to better, targeted treatments.

Leptin helps start the growth phase of hair.

Applying a special DNA plasmid to the skin can make it thicker and stronger.

Cross-sex hormone therapy is important for managing gender dysphoria and requires careful monitoring and healthcare provider education.

Low vitamin D receptor levels found in hair loss patients; topical vitamin D treatment suggested.

A rare ITGB6 gene variant causes intellectual disability, hair loss, and dental issues.

In Japan, sex reassignment surgery for gender identity disorder faces challenges and needs better medical support and education.

Southeast Asian herbs show promise for skin and hair care, but more research is needed to confirm their effectiveness in cosmetics.

Selenium might help with insulin resistance and cholesterol in PCOS, but more research is needed to confirm its benefits.