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Aminopterin was somewhat effective in acute lymphoblastic leukemia in children but did not increase survival time.

Fisetin, a type of polyphenol, may help hair grow by increasing certain protein activities in cells.

New physical methods like electrical currents, ultrasound, and microneedles show promise for improving drug delivery through the skin.

Understanding hair follicle biology and stem cell control could lead to new hair loss treatments.

Facial aging is caused by natural processes and external factors, and can be managed with preventative measures and a variety of treatments tailored to individual needs.

DHEA may help with sexual function when used intravaginally by menopausal women but is similar to hormone therapy in other aspects and might cause more side effects like acne and hair loss.

Low-level laser therapy seems to help dogs with noninflammatory alopecia grow hair back.

Mice genetically modified to produce more CD109 in their skin had less inflammation and better healing with less scarring.

The tropical legume Sesbania rostrata can form nodules in waterlogged conditions using a different method that involves plant hormones and specific genes.

Lack or blocking of SRD5a, a key component in hormone creation, can lead to conditions like pseudohermaphrodism and affect hair growth, bone mass, muscle strength, and reproductive health. More research is needed on its regulation from fertilization to adulthood.

A specific gene change plus an additional mutation in the same gene cause hereditary trichilemmal cysts.

Low-level laser therapy significantly increases hair density in adults with hair loss, with low-frequency treatment being more effective.

The guide explains how to study human skin fat cells and their tissue, aiming to improve research and medical treatments.

Different human hair follicle stem cells grow at different rates and respond differently to a baldness-related compound.

Chromium supplements don't improve insulin, hormone levels, or cholesterol in women with PCOS but raise testosterone levels.

Cognitive-behavioral therapy is the best treatment for hair-pulling disorder, and combining it with other therapies could improve results.

Hormonal contraceptives can help treat acne by affecting sebum production and androgen levels.

Some diseases can improve the outcomes of other diseases, leading to new treatment possibilities.

Stopping fluoride toothpaste use might improve perioral dermatitis.

Spermidine helps protect against aging by preserving telomere length.

Finasteride reduces response to stress and rewards, affecting behavior and mental health.

The research suggests that autophagy-related genes might play a role in causing alopecia areata.

Men with male pattern baldness have a higher risk of certain skin cancers, especially on the scalp.

Scientists made safflower seeds produce a human growth factor that could help with hair growth and wound healing.

Women with polycystic ovarian syndrome are more likely to have cervical insufficiency, especially South Asian and Black women.

The document concludes that there are still unknowns about the effectiveness, risks, and detection of performance-enhancing drugs, and doping remains a challenge.

People undergoing chemotherapy need better support and information to cope with hair loss.

Telomere damage affects skin and hair follicle stem cells by messing up important growth signals.

Non-immune factors play a significant role in alopecia areata.

Poor sleep is linked to a higher risk of developing and worsening urinary problems in men.