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The dog died from myxedema coma linked to severe atherosclerosis and thyroid issues.

People with lower levels of free testosterone tend to have worse COVID-19 outcomes.

The document concludes that understanding how the skin's immune system and inflammation work is complex and requires more research to improve treatments for skin diseases.

Existing drug dexamethasone may lower death risk in severe COVID-19 cases; more research needed for other drugs.

Skin stem cells are maintained by signals from nearby cells and vary in their ability to renew and mature.

The document concludes that more research is needed to understand airway repair and to improve tissue engineering for lung treatments.

A woman lost over 80% of her hair due to a condition called telogen effluvium after having COVID-19.

Epithelial stem cells are crucial for tissue renewal and repair, and understanding them could improve treatments for damage and cancer.

COVID-19 can cause different skin symptoms that may help with early diagnosis and show how severe the disease is.

Testosterone may have a dual role in COVID-19, potentially worsening outcomes in men, and testosterone therapy could help some patients, but more research is needed.

COVID-19 may harm male fertility and damage the reproductive system.

COVID-19 and hypopituitarism (reduced pituitary gland function) are linked, with the latter's related health issues potentially worsening COVID-19 outcomes, and COVID-19 possibly increasing risk for pituitary complications.

Melanocytes are diverse cells important for pigmentation and skin health, influenced by genetics and environment.

Skin reactions are a common reason for emergency visits due to drug allergies, with some severe cases needing intensive care.

The skin's layers protect, sense, and regulate the body's internal balance, but can be prone to cancer.

The secretome from mesenchymal stem cells is a promising treatment that may repair tissue and avoid side effects of stem cell transplantation.

Men are more likely to have severe COVID-19 cases and fatalities than women due to factors like lifestyle, aging, and biological differences.

Tight junctions are key for skin protection and controlling what gets absorbed or passes through the skin.

Matriptase is crucial for keeping epithelial tissues healthy and functioning properly.

Different types of stem cells exist within individual skin layers, and they can adapt to damage, transplantation, or tumor growth. These cells are regulated by their environment and genetic factors. Tumor growth is driven by expanding, genetically altered cells, not long-lived mutant stem cells. There's evidence of cancer stem cells in skin tumors. Other cells, bacteria, and genetic factors help maintain balance and contribute to disease progression. A method for growing mini organs from single cells has been developed.

Men generally have more severe COVID-19 cases and higher death rates than women due to biological differences.

Survivors of Stevens-Johnson syndrome/toxic epidermal necrolysis need ongoing care for various long-term health problems.

Platelet-rich plasma might help tissue regeneration in dentistry, but results vary and more research is needed.

Mutations in Gasdermin A3 cause skin inflammation and hair loss by disrupting mitochondria.

The FOXN1 gene is crucial for developing immune cells and preventing immune disorders.

People with diabetes or obesity should manage their conditions carefully as they have a higher risk of severe COVID-19.

The conclusion is that individual differences in COVID-19 severity are influenced by factors like age, sex, race, and genetics, which are important for personalized medicine.

FOXN1 gene variants cause low T cells and immune issues from birth.

The drug enzalutamide may reduce the ability of the virus causing COVID-19 to enter lung cells.

COVID-19 might affect male fertility, but more research is needed to understand the full impact.