Myxedema Coma and Acute Hepatopathy in a Dog with Severe Atherosclerosis

    Leah C. Giralico, Rebecca Makii, Betsy Pray, Valerie J. Parker
    TLDR The dog died from myxedema coma linked to severe atherosclerosis and thyroid issues.
    A 9-year-old male mixed-breed dog presented with symptoms of weakness, lethargy, and vomiting, and was diagnosed with myxedema coma, acute hepatopathy, and severe atherosclerosis. Despite supportive care, the dog experienced respiratory arrest and was euthanized. Postmortem examination confirmed severe thyroid atrophy, necrotizing cholangiohepatitis, and marked atherosclerosis. The study highlights the complexity of diagnosing and managing multiple concurrent conditions in veterinary practice, particularly the association between hypothyroidism, hyperlipidemia, and atherosclerosis in dogs.
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