8 citations
,
August 2020 in “Clinical and Experimental Dermatology” In this review, spironolactone is highlighted for its emerging use in dermatology, particularly for treating androgen-mediated conditions like acne and hirsutism in susceptible females, though it requires careful monitoring for potential adverse effects.
8 citations
,
May 2019 in “Journal of dermatological treatment” This study found that vismodegib was effective in treating basal cell carcinoma, achieving complete remission in some patients; however, significant side effects often required careful management to prevent therapy suspension, which can lead to resistance.
8 citations
,
January 2017 in “Journal of Biological Chemistry” This study found that astrotactin-2 undergoes unique intramembrane proteolysis during maturation, revealing specific transmembrane topologies and substrate sequence requirements for cleavage.
8 citations
,
January 2008 in “PubMed” This study reports that mesotherapy can lead to serious complications, such as multifocal scalp abscesses and subcutaneous fat necrosis, requiring extensive surgical repair.
7 citations
,
October 2022 in “Journal of Mind and Medical Sciences” This study found that during the COVID-19 pandemic, upper gastrointestinal bleeding cases in Romania were more severe and required rapid and progressive treatment approaches to achieve optimal outcomes.
7 citations
,
July 2021 in “PubMed” This review assesses the role of vitamins A, B, C, and D in treating dermatologic conditions and highlights promising applications, although further research is required to confirm their efficacy.
7 citations
,
October 2009 in “Journal of the American Geriatrics Society” This study found that finasteride may reduce inappropriate sexual behaviors in geriatric patients with vascular dementia and benign prostate hyperplasia without serious side effects, though some patients required additional medications.
7 citations
,
November 2001 in “Journal of Vascular Surgery” This address discusses the evolution of surgical training, emphasizing the need for Vascular Surgery to have an independent board to adjust training requirements and improve specialty education without reporting new research findings.
6 citations
,
April 2025 in “Communications Biology” In this study, researchers used a murine model of irritant contact dermatitis to reveal that hair follicle regions serve as key sites for neutrophil transepidermal migration, which requires MMP-9 expression stimulated by dermal monocytes.
6 citations
,
January 2018 in “Elsevier eBooks” This review outlines the current regulatory framework for cosmetics under the FD&C Act, highlighting that they are less strictly regulated than drugs, but notes potential future changes due to proposed legislations requiring stronger safety measures.
6 citations
,
March 2017 in “Plastic and reconstructive surgery. Global open” This study found that both pretrimmed and direct nonshaven follicular unit extraction techniques are effective for hair transplantation, with pretrimmed having a higher calculated density and longer time requirement than direct.
6 citations
,
January 2013 in “Urology” This case report describes an 8-year-old child with penile tourniquet syndrome due to a constricting thread, which led to partial distal penile amputation and required surgical intervention.
6 citations
,
January 2005 This study evaluated laser excision of the fibrous band for oral submucous fibrosis treatment, noting that while it offers immediate relief, long-term effects require further evaluation due to potential drawbacks.
6 citations
,
January 1977 in “PubMed” This study found that minoxidil, used with beta-blockers and thiazides, effectively reduced blood pressure in patients with severe hypertension, although it required careful management of side effects like sodium retention and increased hair growth.
6 citations
,
March 1975 in “The Journal of Dermatology” In this study, Trichophyton verrucosum was identified as the cause of human ringworm infections mainly affecting farm workers or their families, with lesions most common in winter and requiring specific treatment approaches.
5 citations
,
June 2025 in “Journal of Functional Biomaterials” This study explored recent advancements in 3D bioprinting for head and neck defects, highlighting how bioinks and scaffolds may improve treatment customization and functionality by mimicking native tissue features. The research also examined challenges like biocompatibility and regulatory requirements on the path to clinical use.
5 citations
,
January 2021 in “Daru” This case report highlights a rare instance of severe multi-organ involvement following a single dose of methotrexate for ectopic pregnancy, requiring intensive care but ultimately successfully treated with leucovorin and supportive care.
5 citations
,
March 2017 in “International journal of GEOMATE : geotechnique, construction materials and environment” This study found that incorporating pig-hair fibers and green mussel shells in concrete increased compressive strength but decreased workability, suggesting potential use in structures not requiring strength above 28 MPa.
5 citations
,
March 2016 in “CRC Press eBooks” This article explores the mechanisms of female hirsutism and highlights the effectiveness of eflornithine in reducing hair growth, with further removal requiring physical methods.
5 citations
,
July 2005 in “British journal of dermatology/British journal of dermatology, Supplement” This case study reports an unusual occurrence of hair growth on the glans penis of a healthy 24-year-old man, which required surgical excision but recurred at a different site.
5 citations
,
September 1998 in “Atlas of the oral and maxillofacial surgery clinics of North America” Hair transplantation and micrografting, used for baldness, involve moving hair follicles from hair-rich to bald areas, requiring careful procedure and post-care for success.
4 citations
,
January 2025 in “International Journal of Molecular Sciences” This study found that progesterone and its metabolite, allopregnanolone, provided anti-anxiety and anti-depressive effects in female mice, potentially independent of nuclear progestin receptors but requiring 5α-reduction and estradiol's influence on brain-derived neurotrophic factor.
4 citations
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January 2025 in “Dermatologica Sinica” This consensus from the Taiwanese Dermatological Association suggests that for mild to moderate alopecia areata, first-line treatments may include topical or intralesional corticosteroids, possibly with topical minoxidil, while severe cases might require systemic corticosteroids or Janus kinase inhibitors.
4 citations
,
December 2020 in “IOP Conference Series Materials Science and Engineering” This study analyzed vegetable crops and found beets and potatoes to have high iron content, suggesting they can meet the daily requirements for essential minerals manganese and iron.
4 citations
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December 2020 in “Current sports medicine reports” This article reviews the role of micronutrients in athletes' diets, highlighting that adequate dietary intake generally meets their needs without requiring supplementation, unless deficiencies are present.
4 citations
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March 2020 in “Berkala Ilmu Kesehatan Kulit dan Kelamin” This case report noted that HIV-infected men who have sex with men are at a higher risk of syphilis, requiring careful staging and prolonged serologic monitoring to assess treatment success.
4 citations
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April 2019 in “DOAJ (DOAJ: Directory of Open Access Journals)” This review highlights available treatments for frontal fibrosing alopecia, noting that 5-alpha reductase inhibitors, intralesional steroids, and hydroxychloroquine currently have the most evidence supporting their use, while other treatments show variable results and require further study.
4 citations
,
February 2018 in “Journal of Investigative Dermatology” This study suggests that thermal imaging may aid in diagnosing cellulitis, potentially improving patient care, although its applicability to certain cases requires further investigation.
4 citations
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February 2018 in “Facial Plastic Surgery” In this research, a minimally invasive endoscopic brow lifting technique was presented as a viable option to reshape and fixate heavy eyebrows in mestizo patients, offering an effective approach that requires careful patient analysis to determine the appropriate technique and desired outcomes.
4 citations
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January 2017 in “International journal of trichology” This case study reports that sudden hair matting occurred in a patient after using coconut and castor oils on long hair, requiring the hair to be cut off due to irreversible felting.