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EGFR-TKIs can cause significant skin, nail, and organ side effects.

The hypothesis suggests that PCOS may start early in life due to genetic and environmental factors, influencing future reproductive and metabolic problems.

ATP-dependent chromatin-remodeling complexes are crucial for gene regulation, cell differentiation, and organ development in mammals.

The TGF-β family helps control how cells change and move, affecting skin, hair, and organ development.

Lack or blocking of SRD5a, a key component in hormone creation, can lead to conditions like pseudohermaphrodism and affect hair growth, bone mass, muscle strength, and reproductive health. More research is needed on its regulation from fertilization to adulthood.

The compounds tested could potentially treat hair loss and alopecia.

Melatonin may help with sleep issues, depression, and cancer, but more research is needed.

Polycystic ovary syndrome (PCOS) is a major health issue for women in Egypt, affecting 14% of fertile women and 37.5% of infertile women.

Melatonin affects many body functions beyond sleep by interacting with specific receptors in various tissues.

COVID-19 might affect male fertility, but more research is needed to understand the full impact.

Cognitive behavioral strategies help women with PCOS make lifestyle changes to improve their health.

St. John's Wort extract and oil safety in cosmetics is unclear; more data needed on photosensitization, toxicity, and human irritation.

Lipocalin-Type Prostaglandin D2 Synthase (L-PGDS) is a protein that plays many roles in the body, including sleep regulation, pain management, food intake, and protection against harmful substances. It also affects fat metabolism, glucose intolerance, cell maturation, and is involved in various diseases like diabetes, cancer, and arthritis. It can influence sex organ development and embryonic cell differentiation, and its levels can be used as a diagnostic marker for certain conditions.

Electro-acupuncture may help treat PCOS in rats by changing brain DNA methylation.

The new FDA labeling rules provide more detailed drug safety information for pregnant and breastfeeding women, but more data is needed on the risks of many dermatologic drugs.

Finasteride safely treats hair loss without harming hormones or reproduction, but may slightly reduce sexual function.

Toxoplasma gondii infection may increase testosterone levels in males.

HDAC6 helps keep ovarian follicles dormant, extending female fertility.

The document concludes that understanding hair and feather regeneration can help develop new regenerative medicine strategies.

The document concludes that various drugs can manage symptoms and metabolic issues in women with PCOS.

Finasteride causes lasting fertility decrease in rats.

Melatonin directly affects mouse hair follicles and may influence hair growth.

Ayurvedic treatment can help manage PCOS symptoms.

Testosterone and some of its forms can strongly stimulate oil gland growth in skin.

Platelet-rich plasma shows promise for treating various female reproductive health issues but requires more research.

PCOS is diagnosed when at least two of these three features are present: polycystic ovaries, irregular ovulation, and high androgen levels.

Excess androgens may cause PCOS, not just be a symptom.

PCOS is a complex disorder in women that can lead to various health risks and requires personalized treatment.

Insulin resistance is a key factor in polycystic ovary syndrome, but genetics may also contribute.

Androgen receptors are active in many tissues of both male and female mice, not just reproductive organs.