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Melatonin may benefit skin health and could be a promising treatment in dermatology.

ATP-dependent chromatin-remodeling complexes are crucial for gene regulation, cell differentiation, and organ development in mammals.

Blocking COX, especially COX-2, in the skin can reduce inflammation and pain and may help prevent skin cancer.

Women with PCOS have a higher risk of diabetes and heart problems, especially when they get older.

About 2.2% of women with symptoms of high male hormones have a mild form of congenital adrenal hyperplasia, and measuring a specific hormone level can accurately diagnose it.

The enzyme 25 Hydroxyvitamin D 1 α-Hydroxylase is essential for healthy skin and recovery after skin damage.

Finasteride effectively blocks enzyme causing male pattern baldness.

Targeting androgen receptors could be a promising way to treat skin disorders with fewer side effects.

Finasteride exposure in pregnancy causes genital abnormalities in male rats.

Estrogens help reduce skin aging, and SERMs might offer similar benefits without the risks of hormone therapy.

Most women with PCOS have high levels of male hormones, and free testosterone is the best marker for this.

The update highlights that non-classic congenital adrenal hyperplasia is common in women with excess male hormones, requires specific hormone tests for diagnosis, and has various treatment options depending on age and symptoms.

Combining liraglutide and metformin helps obese women with PCOS who didn't lose weight on metformin alone to lose more weight.

People with PCOS, especially if obese, often have NAFLD, linked to obesity, insulin resistance, and high androgen levels.

Finasteride doesn't harm male fertility or sperm quality, but may slightly reduce ejaculate volume.

Both genes and environmental factors like chemicals may contribute to the increase in hypospadias, but the exact causes are still unclear.

Finasteride effectively treats hidradenitis suppurativa for most patients.

Testosterone replacement may help some postmenopausal women with symptoms like fatigue and low libido, but more research is needed to fully understand its effects.

An mFG score of 5 or more indicates above-normal hair growth in Southern Chinese women.

Testosterone supplements can increase muscle mass and strength in older men with low levels, but long-term effects and risks need more research.

New hormonal contraceptives are safer, have fewer side effects, and offer health benefits for women.

Women with PCOS may take longer to get pregnant but can have a normal family size, and should manage their overall health to reduce long-term health risks.

The TGF-β family helps control how cells change and move, affecting skin, hair, and organ development.

The conclusion is that managing androgen excess requires long-term treatment, including hormonal contraceptives and androgen blockers, with follow-up after six months.

Testosterone therapy seems safe for postmenopausal women for a few years, but more research is needed for long-term effects.

Mice without the vitamin D receptor gene lose hair due to disrupted hair follicle cycles.

Some common medications can harm male fertility, but many effects can be reversed.

New treatments for male hypogonadism are effective and should be personalized.

The circadian clock influences the behavior and regeneration of stem cells in the body.

Beta-sitosterol has potential health benefits but needs more research to fully understand its effects and improve its use in treatments.