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Gonadal dysgenesis, like Turner's and Klinefelter's syndromes, negatively affects bone health, but hormone treatments can help.

Sex hormones may affect COVID-19 severity, with men often faring worse, and targeting related pathways could offer treatment options.

Androgens may influence T cells, contributing to higher autoimmune liver disease risk in women.

Sex hormone treatments can increase muscle mass in older adults but have inconsistent effects on muscle function and may carry cardiovascular risks.

5-alpha-reductase inhibitors may cause a low incidence of erectile dysfunction that decreases over time.

Women generally handle heart enlargement better than men, but it's riskier for them if it occurs; hormones like estrogen offer some protection.

Early medical support for transgender youth is important for their health, with low regret for gender-affirming hormone use and a need for knowledgeable care providers.

The document concludes that non-operative treatment for gender dysphoria is safe and effective, and hormone therapy does not increase cancer risk.

The document concludes that low-dose oral contraceptives and hormonal therapies can manage perimenopause symptoms and reduce some health risks, but lifestyle changes and disease screening are also important.

Blocking 5α-reductase can harm memory and brain structure, and increase harmful brain changes in male mice used for Alzheimer's disease research.

The healthcare for transgender veterans could be better with a more unified team approach.

Steroid hormones are crucial for body functions and have various medical uses, but their misuse can lead to dependence.

Androgens play a key role in hair growth and disorders like baldness and excessive hairiness.

Androgens and androgen receptors are important for metabolic health, affecting how the body uses glucose and fats through mitochondrial function.

COVID-19 may harm male reproductive health and lower testosterone levels, potentially affecting fertility and causing erectile dysfunction. More research is needed.

A 19-year-old male with delayed puberty was successfully treated for a condition that prevents normal hormone production.

The conclusion is that adult males with muscle weakness and hormonal imbalances should be tested for Kennedy's disease.

Future osteoporosis treatments should focus on increasing bone growth, with many promising options available.

COVID-19 and hypopituitarism (reduced pituitary gland function) are linked, with the latter's related health issues potentially worsening COVID-19 outcomes, and COVID-19 possibly increasing risk for pituitary complications.

Certain drugs can worsen hair loss in people prone to androgenetic alopecia.

Using β-cyclodextrin derivatives improves the solubility and bioavailability of steroidal drugs.

There are various effective hormone treatments for puberty induction in boys and girls with hypogonadism, and starting treatment early is important.

Androgen use may increase the risk of stroke, but more research is needed.

Metformin is less effective in men with early-onset hair loss.

Menopause worsens skin, hair, and nails, affecting self-esteem and quality of life.

The guideline recommends mental health involvement in diagnosing gender identity disorder and outlines hormone and surgical treatment protocols, emphasizing safety, informed consent, and long-term monitoring.

Understanding how DHT works is important for diagnosing and treating hormone-related disorders.

Muscles can make their own androgens, which may help muscle growth.

Premature ovarian insufficiency (POI) can harm women's sexual health, and they may benefit from hormone therapy and counseling.

Using anabolic-androgenic steroids can harm men's reproductive health and increase the risk of heart problems and death.