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The document concludes that more research is needed to understand how to treat muscle pain with drugs.

Aging causes changes in the scalp that can affect hair growth and lead to older-looking hair in women.

Using microneedling with PRP improves skin and hair conditions more than microneedling alone.

Longer time setting curls overnight leads to better curl retention.

Esthetic surgery complications can include infections, nerve injury, and more; proper evaluation and technique help prevent them.

Sponge helps heal wounds faster with less inflammation and better skin/hair growth.

Scalp flaps are stiffer than skin from other body areas, which helps in planning reconstructive and cosmetic head surgeries.

Hair's strength and flexibility come from its protein structure and molecular interactions.

Minoxidil might help treat acne scars by reducing collagen buildup.

Keratin proteins are crucial for hair structure and strength.

In 1981, the punch graft technique was the main method for hair transplantation, and medical treatments for baldness were not very effective.

The document concludes that better targeted treatments are needed for wound healing, and single-cell technologies may improve cell-based therapies.

Obesity affects skin health, causing conditions like acanthosis nigricans and may require different treatment approaches.

Calreticulin has roles in healing, immune response, and disease beyond its known functions in the endoplasmic reticulum.

TGF-β is crucial for tissue repair and can cause diseases if not properly regulated.

The skin is a complex barrier for drug penetration, but understanding its structure and interactions can improve drug delivery methods.

Artificial skin development has challenges, but new materials and understanding cell behavior could improve tissue repair. Also, certain growth factors and hydrogel technology show promise for advanced skin replacement therapies.

Lecithin organogels could be good for applying drugs to the skin because they are stable, safe, and can improve drug absorption.

Nanoparticles improve drug delivery through the skin but more research is needed on their long-term effects and skin penetration challenges.

The document concludes that more research is needed to better understand and treat primary cicatricial alopecias, and suggests a possible reclassification based on molecular pathways.

Asia has made significant progress in tissue engineering and regenerative medicine, but wider clinical use requires more development.

Understanding the mouse hair cycle is crucial for cancer research.

Male pattern baldness involves smaller hair follicles, larger oil glands, and other tissue changes, but not major blood supply issues.

Mammals might fail to regenerate not because they lack the right cells, but because of how cells respond to their surroundings, and changing this environment could enhance regeneration.

Advanced hydrogel systems with therapeutic agents could greatly improve acute and chronic wound treatment.

Advanced nanocarrier and microneedle drug delivery methods are more effective, safer, and less invasive for treating skin diseases.

PRP injections may be a safe, effective alternative for hair loss treatment compared to minoxidil and finasteride.

Microneedle technology has improved drug delivery and patient comfort but needs more research for broader use.

Using minoxidil on dogs can cause serious cardiovascular damage, including arterial injury and hemorrhagic lesions.

Multiphoton microscopy is a promising tool for detailed skin imaging and could improve patient care if its challenges are addressed.