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The enzyme steroid sulfatase is linked to breast cancer and other conditions, and inhibitors are being developed for treatment.

Obesity affects skin health, causing conditions like acanthosis nigricans and may require different treatment approaches.

Insulin resistance is a key factor in polycystic ovary syndrome, but genetics may also contribute.

TGF-β is crucial for tissue repair and can cause diseases if not properly regulated.

Stem cells are crucial for skin repair and new treatments for chronic wounds.

Regulatory T-cells are important for healing and regenerating tissues in various organs by controlling immune responses and aiding stem cells.

Oestrogens are key for bone growth during puberty in both boys and girls.

Early diagnosis and individualized treatment improve outcomes for Congenital Adrenal Hyperplasia.

Patients with certain skin symptoms and high ANA titers should be monitored for potential systemic lupus.

Microneedles improve drug delivery in various body parts, are safe and painless, and show promise in cosmetology, vaccination, insulin delivery, and other medical applications.

The conclusion is that PCOS is caused by ovarian sensitivity to hormones and disrupted hormone control, possibly due to ovarian factors, and more research is needed.

Allergic reactions to blood thinners are rare but can be serious, requiring careful testing and alternative treatments.

The update highlights that non-classic congenital adrenal hyperplasia is common in women with excess male hormones, requires specific hormone tests for diagnosis, and has various treatment options depending on age and symptoms.

The article concludes that the wool follicle is a valuable model for studying tissue interactions and has potential for genetic improvements in wool production.

Prolactin affects hair growth and skin conditions, and could be a target for new skin disease treatments.

Prolactin affects hair growth cycles and can cause early hair follicle regression.

The document explains how the male reproductive system works, its role in making testosterone, and how conditions like obesity can disrupt it, leading to low testosterone and fertility issues.

Blocking the enzyme 11β-HSD1 might help treat obesity and metabolic issues.

European guidelines recommend regular eye and ear exams, skin care, vitamin D supplements, and cautious use of medications for managing congenital ichthyoses.

There are still challenges in diagnosing and treating chronic skin diseases, but there is hope for future improvements.

Chemotherapy often causes hair loss, nail changes, and mouth issues, but these are usually manageable.

Targeting glucocorticoid action might help treat type-2 diabetes, but human trials are needed.

Some medications can cause acne, and stopping these drugs is the main treatment.

Botox increased hair count in men with baldness and might work by improving scalp blood flow.

Equisetum debile extract, especially the ethyl acetate type, may be a promising natural ingredient for anti-hair loss products.

Natural 5α-reduced glucocorticoids might be anti-inflammatory with fewer side effects than current options.

The research found that polycystic ovary syndrome (PCOS) has two distinct types, with one having more severe hormone and insulin issues.

Leptin, a hormone, is important for starting hair growth.

Neuroactive steroids show promise for treating mental and neurological disorders by targeting GABA_A receptors.

Drug repurposing is a cost-effective way to find new uses for existing drugs, speeding up treatment development.