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      PAK4 Signaling in Health and Disease: Defining the PAK4–CREB Axis

      research PAK4 signaling in health and disease: defining the PAK4–CREB axis

      81 citations , February 2019 in “Experimental & Molecular Medicine”
      This review examines PAK4 signaling pathways in prostate cancer, Parkinson's disease, and melanogenesis, focusing on the potential role of the PAK4-CREB axis, without reporting new clinical results.
      Emerging Roles of Transit-Amplifying Cells in Tissue Regeneration and Cancer

      research Emerging roles of transit‐amplifying cells in tissue regeneration and cancer

      32 citations , July 2017 in “Wiley Interdisciplinary Reviews-Developmental Biology”
      This review discusses the emerging roles of transit-amplifying cells in tissue regeneration and cancer formation, highlighting their significance beyond a mere transitional state in hair follicles and the hematopoietic system.
      Epidermal Growth Factor, Innovation and Safety

      research Epidermal growth factor, innovation and safety

      10 citations , October 2015 in “Medicina Clínica (english Edition)”
      This review discusses the therapeutic potential and safety of bioidentical recombinant human epidermal growth factor (rhEGF) for various skin and mucosa conditions and reports no new clinical results.
      British Hair and Nail Society Findings on Hair and Nail Disorders

      research British Hair and Nail Society

      1 citations , July 2016 in “British Journal of Dermatology”
      Men with a certain type of hair loss often use facial moisturizers, and a specific antibiotic treatment may help another hair condition.
      Vitamin D and Human Health: Lessons from Vitamin D Receptor Null Mice

      research Vitamin D and Human Health: Lessons from Vitamin D Receptor Null Mice

      1533 citations , October 2008 in “Endocrine reviews”
      This research highlights that engineered mice lacking the vitamin D receptor show multiple health issues similar to human vitamin D deficiency, underscoring the widespread impacts of the vitamin D endocrine system.
      Scratching the Surface of Skin Development

      research Scratching the surface of skin development

      788 citations , February 2007 in “Nature”
      This review explores how adult skin epithelia preserve stem cell populations for hair follicle regeneration and wound healing, but reports no new experimental results.
      Vitamin D Receptor: New Assignments for an Already Busy Receptor

      research Vitamin D Receptor: New Assignments for an Already Busy Receptor

      510 citations , August 2006 in “Endocrinology”
      This minireview discusses a proposed model of the vitamin D receptor that explains how 1alpha,25(OH)2D3 can mediate both genomic and rapid responses through different ligand shapes and cellular locations, without presenting new research findings.
      Stem Cells and the Niche: A Dynamic Duo

      research Stem Cells and the Niche: A Dynamic Duo

      333 citations , February 2010 in “Cell Stem Cell”
      This review discusses experimental data, technologies, and genetic factors related to stem cell niches, highlighting their role in tissue regeneration and diseases, but reports no new results.
      Transforming Growth Factor-Beta in Stem Cells and Tissue Homeostasis

      research Transforming growth factor-β in stem cells and tissue homeostasis

      245 citations , January 2018 in “Bone Research”
      This review discusses the role of TGF-β signaling in stem cell recruitment and tissue regeneration, indicating that abnormalities in TGF-β activation contribute to various major diseases and suggesting avenues for therapeutic intervention.
      Wnt Signaling and Injury Repair

      research Wnt Signaling and Injury Repair

      232 citations , June 2012 in “Cold Spring Harbor Perspectives in Biology”
      This review summarizes the roles of Wnt signaling in wound healing but presents no new clinical findings, suggesting potential for Wnt-based therapies to enhance tissue regeneration.
      Eph Receptors and Ephrins: Therapeutic Opportunities

      research Eph Receptors and Ephrins: Therapeutic Opportunities

      222 citations , October 2014 in “Annual Review of Pharmacology and Toxicology”
      This review discusses the roles of Eph receptors and ephrins in various diseases, highlighting their potential as therapeutic targets, but it presents no new research findings.
      More Than One Way to Skin

      research More than one way to skin . . .

      218 citations , April 2008 in “Genes & Development”
      This research discusses how epithelial stem cells in the skin maintain normal homeostasis, contribute to wound repair, and highlights the importance of these processes, as defects can lead to skin diseases including cancers, but provides no new experimental results.
      A Hot New Twist to Hair Biology: The Role of TRPV1 in Human Hair Growth Control

      research A Hot New Twist to Hair Biology

      174 citations , April 2005 in “˜The œAmerican journal of pathology (Print)”
      This study found that TRPV1 activation in human scalp hair follicles inhibited hair shaft elongation, suppressed proliferation, and induced apoptosis, suggesting TRPV1 as a potential target for managing hair growth and epithelial disorders.
      Zinc Therapy in Dermatology: A Review

      research Zinc Therapy in Dermatology: A Review

      165 citations , January 2014 in “Dermatology Research and Practice”
      This review discusses the various dermatological applications of zinc, including its use in treating infections, inflammatory dermatoses, pigmentary disorders, and neoplasias, and reports no new clinical findings.
      Hair Follicle Stem Cells: Walking the Maze

      research Hair follicle stem cells: Walking the maze

      165 citations , June 2007 in “European Journal of Cell Biology”
      This review discusses the various stem cell populations associated with hair follicles and their potential in regenerative medicine, highlighting differences between murine and human hair follicles but reports no new clinical results.
      The Hair Follicle as an Estrogen Target and Source

      research The Hair Follicle as an Estrogen Target and Source

      159 citations , July 2006 in “Endocrine Reviews”
      This article discusses the influence of estrogens on hair follicle growth and metabolism, suggesting a significant role alongside androgens in hair growth control but reports no new clinical results.
      The Harmonies Played by TGF-β in Stem Cell Biology

      research The Harmonies Played by TGF-β in Stem Cell Biology

      156 citations , December 2012 in “Cell Stem Cell”
      This review explores the role of TGF-β superfamily pathways in stem cell environments and their implications for tissue regeneration and cancer development, reporting no new experimental results.
      Molecular Mechanisms of Viral Oncogenesis in Humans

      research Molecular mechanisms of viral oncogenesis in humans

      141 citations , August 2018 in “Nature Reviews Microbiology”
      This review discusses the molecular mechanisms by which oncogenic viruses contribute to cancer development through manipulation of host cellular functions and highlights the need for further research into virus-associated cancers, reporting no new results.
      TGF-β Family Signaling in Stem Cells

      research TGF-β family signaling in stem cells

      132 citations , August 2012 in “Biochimica et Biophysica Acta (BBA) - General Subjects”
      This review discusses the roles of TGF-β family signaling in regulating normal and cancer stem cells and highlights the need for further research to develop potential cancer treatments; it reports no new results.